[Next-Generation Sequencing Book]
  • [Photo] Xiaojun Li • February 18, 2010

    BACKGROUND

    The mission of Integrated Diagnostics is to leverage powerful emerging technologies in the development of diagnostic products that enable physicians and patients to manage complex and important diseases such as cancer, lung disease and CNS diseases through blood tests that can monitor tens to hundreds of disease markers simultaneously. Integrated Diagnostics was founded by Lee Hood of the Institute for Systems Biology.

    RESPONSIBILITIES

    Integrated Diagnostics, a molecular diagnostics company, seeks to add a Bioinformatician to join our growing team. The Bioinformatician is a member of the scientific team responsible for selecting biomarker candidates on targeted diseases, analyzing proprietary and public datasets derived from genomic, transcriptomic, and proteomic analyses, and providing bioinformatics support for all company projects. The position reports to the Director of Bioinformatics.

    Responsibilities include but are not limited to:
    • Developing software to automate data analysis and data mining
    • Analyzing large-scale genomics, transcriptomics, and proteomics datasets to support the identification and the validation of biomarker candidates
    • Developing software to facilitate the mining of public and private knowledge databases such as PubMed, DAVID, Ingenuity, cancer genome atlas, Gene Ontology, OMIM, iHOP, EntrezGene, etc.
    • Collecting and managing information from public data repositories such as PeptideAtlas, GEO, caBIG, etc.
    • Performing pathway/network analysis on genes or proteins of interest
    • Developing informatics to store crucial information on biomarker candidates and build user-friendly interfaces for others to mine the data
    • Documenting and reporting progress in timely fashion
    • Exploring and learning new bioinformatics tools developed by others

    REQUIREMENTS

    • A MS or Ph.D. degree in bioinformatics, computer science, mathematics, physics, statistics, or engineering is required.
    • A minimum of 3 years of industrial work experience participating within a team oriented environment
    • Strong programming skills and proficiency with script languages (such as PERL) and computing languages (C, C++, or Java) are essential.
    • Experience with Excel, pathway/network analysis, data management, and data mining on public databases is required.
    • The ideal candidate would be collaborative, reliable, creative, curious, a team player, and a self-motivator.
    • He/she must have good interpersonal and communications skills; be adaptable to changing work requirements, willing to multi-task, and eager to take new challenges; hold high degree of professional integrity.

    PREFERENCES

    • Record of developing new bioinformatics tools is preferred.
    • Hands-on experience on analyzing large-scale genomic, transcriptomic and/or proteomic datasets is desirable.
    • Experience on analyzing large-scale mass spectrometry datasets is a huge advantage.
    • Working knowledge on relational database, R/Bioconductor, and Matlab are assets.
    • Ability to work under both Windows and Linux/Unix systems is a plus.

    HOW TO APPLY

    For consideration, please email a resume to hr[at]integrated-diagnostics.com.

    Integrated Diagnostics is an EOE and offers a competitive salary. For more information on Integrated Diagnostics, please visit our website http://www.integrated-diagnostics.com.

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