BACKGROUND:
SAIC-Frederick, Inc., is a wholly owned subsidiary of Science Applications International Corporation (SAIC). As prime contractor for the National Cancer Institute’s research and development center in Frederick, MD, this national laboratory is dedicated to rapidly translating basic research into new technologies for diagnosing, treating, and preventing cancer and AIDS. SAIC-Frederick maintains a full suite of advanced technologies in areas such as nanotechnology, genomics and imaging; operates the federal government’s only drug and vaccine manufacturing facilities; operates the high-performance Advanced Biomedical Computing Center; and supports more than 300 clinical trials for patients in the US and around the world.

RESPONSIBILITIES:
THIS IS AN AMERICAN RECOVERY AND REINVESTMENT ACT (ARRA) FUNDED POSITION.

The Clinical Services Program (CSP) provides technical and operational support to the NCI's Office of Biorepository and Biospecimen Research (OBBR) while they establish the Cancer Human Biobank (caHUB). caHUB’s primary mission is to ensure the adequate and continuous supply of human biospecimens of measurable quality to the biomedical research community. caHUB will be initially established as a pilot endeavor using SAIC-Frederick subcontractors that are funded by the American Recovery and Reinvestment Act (ARRA).

Individual will be responsible for all statistical tasks and performing them with a high level of independence but also needs to work within caHUB as a team player. The Biostatistician will work closely with customer service and business development personnel to design/establish new projects or track existing ones. In particular, will contribute to the development of an accrual plan for building the caHUB benchmark collections. Reviews protocols for completeness, appropriateness of clinical design and sound statistical analysis. Will develop statistical analysis plans and then guide cross-functional caHUB teams during their integration and implementation. Will provide biostatistics expertise in study design, including sample size estimation, power calculation and sample randomization procedures that are needed for working with clients who are interested in using caHUB specimen acquisition, processing, pathology evaluation and testing services.

Will provide biostatistical analyses and support in collaboration with the statistical analysis provided by the caHUB client/customer so it is complementary and/or confirmatory. Will serve as an expert point of statistical reference for the caHUB biospecimen community. Will maintain a network of biostatics expert contacts to enlist their professional expertise, if and when needed. Will use all commonly available classic and contemporary statistical and computing methodologies, e.g., multivariate analysis, nonparametric techniques, data mining and simulation. Will obtain, review and interpret the necessary project background and rationale, identify/define hypotheses, endpoints and covariates, assist in the design of experiments and surveys, write and evaluate statistical considerations for service proposals, conduct interim project analysis, be able to make and/or advise continuation/stopping decisions for projects.

Will prepare, verify, perform quality-control checks and present results in tables, listings and graphs at meetings and conferences and author the statistical analysis for manuscripts and reports (interim and final). Will also perform statistical quality control analysis on process metrics obtained from Biospecimen Source Sites (BSS), laboratory and pathology operations. Will also be responsible to ensure consistency in statistical methodology, programming standards, and data specifications with all studies and operations for both the pilot (subcontractor operated) and permanent (public private partnership) caHUB. Reviews specification documents in data collection, integration and clean-up to ensure quality of data.

REQUIREMENTS:

• Masters Degree from an accredited college/university in Statistics, Mathematics or related discipline or six (6) years related experience in lieu of degree
• Foreign educated candidates who have completed part or all of their education outside of the United States must have their foreign education evaluated by an SAIC-Frederick-approved accrediting organization to assure that it has met the equivalency of the qualifications of degree work in the United States.
• In addition to education requirements, a minimum of two (2) years of related experience in data analysis and data management is required.
• Must have thorough understanding of statistical principles and methodologies with ability to practice and implement them as needed to determine sample size for various analysis.
• Needs knowledge of medical/biological terminology and experimental designs as related to sample selection and size.
• Conversant with SAS programming, and detailed knowledge of SAS procedures and other statistical software
• Excellent interpersonal, organizational and multi-tasking skills
• Demonstrated track record in relevant publications
• Proven leadership skills and ability to work within cross-functional/matrixed teams

PREFERENCES:

• Excellent written and verbal communication skills
• Good organizational skills and the ability to adapt and adjust to changing priorities
• Previous experience in working with various biological specimens
• Ability to identify cases and controls for small and large studies, e.g., cancer clinical trials and cancer epidemiological studies
• Background medical knowledge, preferably in oncology

LOCALE: Rockville, MD

HOW TO APPLY:
Please visit http://www.saic-frederick.com/careers for more information and to apply.

ARTICLE: Req ID 180962