RESPONSIBILITIES:
Division: Genomics Division
Department: Production Genomics

The DOE Joint Genome Institute (JGI) in walnut Creek, CA has an exciting opportunity available for an experienced Bioinformatics Analyst. Duties include performing thorough quality and assembly analysis of DNA sequence data produced by the new generation of sequencing machines. Focus will be on analysis of metagenomic, plant, fungal, and microbial sequence data. Will implement improvements to data analysis systems, assess and improve existing tools, develop new tools for general use, and provide technical and analytical interpretation of data. May also provide custom analysis support to external collaborators and supervise non-exempt group members. Will report to the QC/QA Group Lead.

Specific Job Duties:
Sequence Analysis and Interpretation:

• Perform quality analysis of sequence data and assist others in interpretation of analyzed data.
• Define quality metrics for assessing library and sequencer performance.
• Independently and proficiently utilize genome assemblers (such as Velvet, Newbler etc), visualization tools, and other genome assembly and analysis software.
• Evaluate assembly results and recommend ways to improve genome assemblies.
• Provide high quality data to collaborators.
• Provide clear and concise professional reports on data analysis and results.
• Work closely with scientists and production staff to improve production line quality.
• Present technical and analytical status in weekly meetings.

Bioinformatics Tool Development:

• Develop and improve tools to evaluate quality of data generated by various sequencing platforms and library types.
• Refine and improve existing analytical tools.
• Design and build new tools to analyze assembled sequences of various research projects.
• Troubleshoot complex system and data analysis problems and provide feedback on areas of improvement for existing tools.
• Provide technical support to implement new sequence analysis pipelines.
• Provide high quality documentation for newly developed software and approaches

REQUIREMENTS:
Key Success Factors:
Essential:

• Typically requires a B.S. in Biology, Bioinformatics, Computer Science or a related field and at least five years of experience in genome assembly or bioinformatics and finishing; or an equivalent combination of education and experience.
• Strong background in biology and biochemistry.
• Strong background in bioinformatics, mathematics, molecular biology and genomics.
• Demonstrated experience applying statistics to analyze large biological datasets.
• Proficiency with programming languages including Perl, C/C++, Java or others in a Unix environment.
• Experience with cluster computing.
• Demonstrated analytical skills sufficient to troubleshoot complex system and data analysis problems and make recommendations.
• Strong organizational and record-keeping skills.
• Effective oral and written communication and interpersonal skills.
• Ability to work independently and as a team member in a diverse multi-disciplinary team environment.
• Ability to handle multiple tasks in parallel while working on a large number of projects.
• Ability to follow laboratory safety guidelines.

PREFERENCES:

• Knowledge and experience with laboratory DNA sequencing technologies and genetics, or related field or equivalent experience preferred.
• Some experience with database structure and management.
• Experience applying machine learning, pattern recognition, or modeling to scientific problems.
• Experience in a multi-disciplinary scientific or production environment.

TERMS:
This is a full-time two-year term appointment with the possibility of renewal and the possibility of conversion to career contingent upon satisfactory performance, continued work, and funding availability. The work schedule may include off-hours and/or weekends. Work will be performed at the DOE Joint Genome Institute (JGI), Production Genomics Facility (PGF) located in Walnut Creek, CA. Detailed information about the Joint Genome Institute program can be found at: http://www.jgi.doe.gov.

LOCALE: Walnut Creek, CA

HOW TO APPLY:
To apply please click the link below to be redirected to the lab job posting, then following the online instructions to complete the application process.

http://www.jobclub.com/banman/a.aspx?ZoneID=0&BannerID=554&AdvertiserID=43&CampaignID=2185&Task=Click&SiteID=1&RandomNumber=277735

POLICY:
Berkeley Lab is an affirmative action/equal opportunity employer committed to the development of a diverse workforce.