[Next-Generation Sequencing Book]
  • [Photo] Helen Norfleet-Shiflett • October 14, 2010

    RESPONSIBILITIES

    The Department of Biochemistry & Molecular Genetics at the University of Virginia seeks applicants for a Research Scientist to develop an analysis pipeline for epigenomic and transcriptome data generated on the Illumina high-throughput sequencing platform. The incumbent also develops methods and software to mine the data including comparison to annotations, clustering, Gene Ontology/Pathway analysis, motif/sequence analysis and application of machine learning techniques to characterize combinatorial regulation of gene expression via methylation and other epigenetic factors.

    REQUIREMENTS

    • Candidates must have a Ph.D., in a related-field and experience in developing statistical methods and implementing them in a computational pipeline to identify significant DNA methylation and histone modification changes in the human and mouse genomes.
    • PhD in bioinformatics, computer science or statistics or other related fields with formal training in molecular biology concepts; Candidates with a Ph.D. in physics, mathematics or chemistry that have strong programming and statistical analysis experience
    • Minimum of 2-3 years experience programming in Perl (or another scripting language), C/C++, and R (or Matlab) and formal training/understanding of statistics
    • Strong publication record and demonstrated scientific track record
    • Minimum 2-3 years experience with next generation sequencing, microarrays or other high-throughput biology is required.
    • Minimum 2-3 years experience and familiarity with epigenetic regulation of gene expression and analysis of related data sets is required.

    HOW TO APPLY

    To apply, visit https://jobs.virginia.edu and search on Posting Number 0606458. Complete a Candidate Profile online, attach a cover letter, curriculum vitae, letter of research interest and contract information for three references.

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