[Next-Generation Sequencing Book]
  • [Photo] Sam Bowker • December 8, 2010

    BACKGROUND

    The Wellcome Trust Sanger Institute is a world leader in genomic research, with an expanding scientific programme dedicated to understanding gene function in health & disease.

    As part of the Sanger Pathogen Genetics Programme, we are building a software platform to process, analyse and explore huge amounts of genomic data that could be the key to eradicate malaria, a potentially fatal disease which affects almost half a billion people every year. We are combining large-scale epidemiological studies with high-throughput analysis of genome variation to systematically search the malaria parasite, their mosquito vector and the human host genomes for novel alleles that affect disease progression. These insights will be critical for the control of antimalarial drug resistance, the development of new drugs, and ideally, an effective vaccine against this disease.

    The massive size of our datasets, which are generated both within Sanger and in collaboration with our partners at Oxford University and other sites, generate issues of scalability and performance on all levels, from data storage to front end. It is our aim to provide universal access of our data to the general scientific community; therefore our platform is completely oriented to the web and should be flexible enough to be used with several different organism genomes. We offer to our users, amongst other things, real-time analysis, visualisation and data management tools.

    REQUIREMENTS

    We are looking for a passionate and creative experienced programmer to help us face the challenges that a huge project like this generates. It is fundamental that you have an understanding of the biological foundations and have strong communication skills with a willingness to work collaboratively in a team setting. As we are using a large spectrum of different technologies, flexibility and dynamism is essential. You should be able to work at any level of the system, such as optimizing back-end algorithms, building visualization tools, processing massive data sets, analysing the performance of the database and managing meta-data.

    Essential Skills:
    • Basic, or better, experience of computing on Unix systems
    • Perl programming, with experience of OO Perl
    • Programming or database development experience
    • At least one of HTML/CGI/Javascript programming experience
    • Good communication skills
    • Keen eye for detail
    • Ability to work unsupervised to a high standard
    • Strong analytical and problem-solving skills

    PREFERENCES

    • Degree in biological science and research experience in a genetics or related field
    • Postgraduate qualification in computing/bioinformatics
    • One or more of C/ C++ / JAVA programming experience
    A more detailed description of required skills and experience is outlined in the role profile.

    TERMS

    This position is fixed-term for 3 years.

    COMPENSATION

    Salary range GBP 27316 to 37690 pa dependent on experience.

    The Institute has excellent purpose built facilities on the Genome Campus, Hinxton on the outskirts of Cambridge. We offer a comprehensive range of benefits including a final salary pension scheme and excellent on-site facilities. Further details can be found on our website https://jobs.sanger.ac.uk.

    HOW TO APPLY

    We are really excited about our work, so, if you share our excitement about solving problems that can make a difference send us your CV along with a cover letter explaining what your interests are. We would be delighted to see any piece of your work. If you develop software for fun or have any system up and running from a previous job please don't hesitate to send us programs, code, a link to your web site or anything else that you are proud of.

    For further information please contact Bronwyn MacInnis on bm2[at]sanger.ac.uk

    To submit your CV and apply for this job please go to https://jobs.sanger.ac.uk to register and apply on line.

    http://twitter.com/sangerinstjobs/

    DEADLINE

    This position will remain open until filled.

Discussion forums: Opportunity: Senior Software Developer, Pipeline (#80746) @ Wellcome Trust Sanger Institute--Hinxton/Cambridge, UK

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