[Next-Generation Sequencing Book]
  • [Photo] Sam Bowker • December 8, 2010

    BACKGROUND

    The Wellcome Trust Sanger Institute is a world leader in genomic research, with an expanding scientific programme dedicated to understanding gene function in health & disease.

    As part of the Sanger Pathogen Genetics Programme, we are building a software platform to process, analyse and explore huge amounts of genomic data that could be the key to eradicating several diseases which are prolific in the developing world. Our team is involved in a number of major high profile collaborations worldwide investigating methods for developing vaccines against typhoid, dysentery, malaria, and tuberculosis by way of large-scale clinical epidemiology and cutting-edge sequencing technology. We are combining this with novel and user-friendly web applications to manage, analyze and share this data.

    The massive size of our datasets generates issues of scalability and performance on all levels, from data storage to front end. It is our aim to provide universal access to our data for the general scientific community; therefore our platform is completely oriented to the web and should be flexible enough to be used with several different organism genomes. We offer to our users, amongst other things, real-time analysis, visualization and data management tools.

    REQUIREMENTS

    We are looking for a passionate and creative experienced programmer to help us face the challenges that a huge project like this generates. It is fundamental that you have an understanding of the biological foundations and have strong communication skills with a willingness to work collaboratively in a team setting. As we are using a large spectrum of different technologies, flexibility and dynamism is essential. You should be able to work at any level of the system, such as optimizing back-end algorithms, building visualization tools, processing massive data sets, analysing the performance of the database and managing meta-data.

    Essential Skills:
    • Experience of computing on Unix systems
    • Experience programming in JAVA
    • Experience designing large OO systems (design patterns, anti-patterns, etc.)
    • Back-end web programming experience (Struts framework and Tomcat server)
    • Front-end web programming experience (HTML/CSS/JS)
    • Experience dealing with relational databases (MySQL).
    • Strong communication skills
    • Keen attention to detail
    • Ability to work as part of a developing team or unsupervised to a high standard
    • Strong analytical and problem-solving skills

    PREFERENCES

    • Postgraduate qualification in computer science or similar
    • Degree or experience in biological science
    • Degree or experience in bacterial or pathogen genetics, phylogeny or evolution
    • Experience using sequence annotation and assembly software
    • Experience in SNP visualisation and analysis software and databases
    • Perl programming, with experience of OO Perl
    • Programming or database development experience
    • C or C++ programming experience
    A more detailed description of required skills and experience is outlined in the role profile.

    TERMS

    This position is fixed-term for 3 years.

    COMPENSATION

    Salary range GBP 27316 to 37690 pa dependent on experience.

    The Institute has excellent purpose built facilities on the Genome Campus, Hinxton on the outskirts of Cambridge. We offer a comprehensive range of benefits including a final salary pension scheme and excellent on-site facilities. Further details can be found on our website https://jobs.sanger.ac.uk,

    HOW TO APPLY

    We are really excited about our work, so, if you share our excitement about solving problems that can make a difference send us your CV along with a cover letter explaining what your interests are. We would be delighted to see any piece of your work. If you develop software for fun or have any system up and running from a previous job please don't hesitate to send us programs, code, a link to your web site or anything else that you are proud of.

    For further information please contact Bronwyn MacInnis on bm2[at]sanger.ac.uk

    To submit your CV and apply for this job please go to https://jobs.sanger.ac.uk to register and apply on line.

    http://twitter.com/sangerinstjobs/

    DEADLINE

    This position will remain open until filled.

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