[Next-Generation Sequencing Book]
  • [Photo] Lauri Rimorin • February 2, 2011

    BACKGROUND

    SAIC-Frederick, Inc., is a wholly owned subsidiary of Science Applications International Corporation (SAIC). As prime contractor for the National Cancer Institute's research and development center in Frederick, MD, this national laboratory is dedicated to rapidly translating basic research into new technologies for diagnosing, treating, and preventing cancer and AIDS. SAIC-Frederick maintains a full suite of advanced technologies in areas such as nanotechnology, genomics and imaging; operates the federal government's only drug and vaccine manufacturing facilities; operates the high-performance Advanced Biomedical Computing Center; and supports more than 300 clinical trials for patients in the US and around the world.

    RESPONSIBILITIES

    THIS IS AN AMERICAN RECOVERY AND REINVESTMENT ACT (ARRA) FUNDED POSITION. The Patient Characterization Center-Clinical Assay Development Center (PCC-CADC) focuses on development and application of novel genomic assays for clinical applications. The Bioinformatics Analyst III is responsible for providing bioinformatics support to the PCC-CADC including the analysis and interpretation of high throughput genomic data such as multi-platform next-generation sequencing data and microarray data sources. Provide biological interpretation of analysis results including mutation impact assessment, expression analysis, prioritization of identified loci/gene lists, classification model building and applying for prediction, and correlation with clinical data derived from patients. Interact with investigators throughout entire experimental process from design to results interpretation and manuscript preparation. Promote community of shared resources through team cooperation.

    This position will work closely with the Advanced Biomedical Computing Center (ABCC) which is a part of the Information Systems Program at SAIC-Frederick. The ABCC provides technology development, scientific consultation, collaboration and training, and high-performance computing support to the NCI and NIH scientists and staff. Coordinate and integrate derived applications and databases with existing efforts within the larger group including the Bethesda, Frederick, Rockville and Gaithersburg NCI campuses.

    REQUIREMENTS

    • Possession of a Bachelors degree (Masters degree preferred) in biomedical science/bioinformatics/math/computer related field from an accredited college or university or four (4) years related experience in lieu of degree
    • Foreign educated candidates who have completed part or all of their education outside of the United States must have their foreign education evaluated by an SAIC-approved accrediting organization to assure that it has met the equivalency of the qualifications of degree work in the United States.
    • In addition to education requirements, a minimum of six (6) years related experience in a biological research laboratory environment with a strong background in bioinformatics application development
    • The candidate must possess experience in next generation sequence analysis, microarray analysis and experience with analysis of large genomic data sets including integration with data available from public or private sources.
    • Hands-on experience in data processing and analyzing sequencing and expression and other array data including polymorphism discovery and impact assessment are also essential.
    • Proficiency in Unix (linux), scripting and programming languages such as R, C, JAVA, SQL and bioinformatics tools and databases is essential.
    • Strong in statistical analysis of biological data
    • Experience working in a team-oriented environment and excellent communication skills are also required.
    • This position is subject to obtaining a Public Trust Clearance.

    PREFERENCES

    • Experience in next-generation sequencing data analysis
    • Experience in molecular biology technologies
    • Experience in data integration, database construction, application development and visualization
    • Experience in porting applications to web environment and working with workflow tools and applications also desired

    LOCALE

    Frederick, MD

    HOW TO APPLY

    Please visit http://www.saic-frederick.com/careers

    ARTICLE

    Req ID 192733

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