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BACKGROUND
SRA conducts, coordinates, and analyzes clinical and experimental studies to inform health research. This practice area addresses preventative, diagnostic, and therapeutic issues in a public health context, including research in cancer, asthma, allergies, diabetes, infectious diseases, genomics, nutrition, reproductive health, and environmental health.RESPONSIBILITIES
This position is with the NextGen Biocomputing Support Project. The main biocomputing/bioinformatics focus areas that will be addressed as part of this project include:- Comparative sequence analysis of influenza genomes
- Molecular evolution analysis
- Analysis of deep sequencing (454) influenza genome data to include graph and cluster analysis (next generation viral sequencing)
- Analysis of third generation (Pacific Biosystems) native viral genome data
- Large scale text mining of literature to improve overall research efficiency
- Determination of antigenic variants related to structure for vaccine strain selection
- Research database design, development, implementation, and testing
- Assistance with administration of biocomputing servers, file storage systems, and HPC GPU cluster
- Develop novel (and modify/improvise existing) data analysis pipeline, data visualization techniques for Next-Gen sequencing and phylogenetic analysis.
- Implement data flow for automated analysis of high-throughput data.
- Develop variety of software programs for bioinformatics and quantitative modeling of biological data.
- Write and maintain technical system documentation, with emphasis on programming problems and resolutions for future reference.
REQUIREMENTS
- Required Years of experience (min): 1-2
- Required Degree: Masters
- Required: Basic Qualifications: Bioinformatics or associated degree, programming proficiency in scripting languages (Perl, Python), R, C/C++, JAVA, Javascript, CGI, web programming.
- Experience developing bioinformatics software, mainly for NextGen sequencing analysis
- Proficiency in Perl, CGI, C/C++, JAVA, Javascript, web programming, Matlab, R
- Experience working in a UNIX or Linux environment
- Experience with Oracle, MySQL, PostgreSQL databases
- Follow a disciplined approach to programming and software quality assurance
- Experience with setting up cron jobs to update bioinformatics databases
- Ability to work independently as well as in a dynamic team of specialists; take challenging projects and deliver results within deadlines
- Ability to work on multiple tasks/projects and communicate effectively
PREFERENCES
- Extensive programming experience with data analysis and visualization techniques for NextGen sequencing and phylogenetic datasets
- Familiarity with bioinformatics tools like JBrowse, Bowtie, MrBayes, PhyML, etc.
- PhD degree in Computational Biology
TERMS
Position Type: Bioinformatics Software Engineer
Start Date: 03-21-2011
Duration: Full Time
Status: openHOW TO APPLY
You MUST go to http://www.sra.com/careers/search.php and enter 32273BR in the Requisition Number box. Also email Corky_Harris[at]sra.com
Contact Information:
SRA International, Inc.
Corky Harris
Corky_Harris[at]sra.com
http://www.sra.com
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