[Next-Generation Sequencing Book]
  • [Photo] Sam Bowker • February 25, 2011

    BACKGROUND

    The Wellcome Trust Sanger Institute is a world leader in genomic research, with an expanding scientific programme dedicated to understanding gene function in health & disease.

    The vertebrate annotation group at the Sanger Institute leads the world in the definition of genesets, and is the lead institute in the GENCODE consortium of the NIH funded ENCODE project. The process to create this annotation involves manual curation, different computational analysis and targeted experimental approaches. Putative loci can be verified by wet-lab experiments and computational predictions analysed manually.

    RESPONSIBILITIES

    The role of the project coordinator is to design and implement the informatics systems required by the ENCODE annotation project to enable data exchange between partners, to give advice and to interact with the ENCODE community and coordinate project data exchange activities. The coordinator is also responsible for submission of data to UCSC DCC and also is involved with QC of the Ensembl/Havana gene merge and maintenance of the Annotrack QC databases to produce the GENCODE reference human gene set (http://www.gencodegenes.org).

    REQUIREMENTS

    This ideal candidate will be an individual who can work independently carry out computational scientific analysis of data reacting quickly to arising needs, new deadlines and rescheduling work accordingly.

    Essential Skills:
    • PhD degree which includes a substantial component in bioinformatics or computer science (or equivalent experience)
    • Substantial experience in the analysis and manipulation of large datasets, such as accessing data via MySQL or commonly used bioinformatics APIs, such as Ensembl, bioperl or biojava.
    • Expert knowledge of BIOMART and DAS systems.
    • Proven record of writing analysis programs and scripts to rapidly investigate scientific questions.
    • Ability to work independently to carry out data analysis
    • Excellent attention to detail and good communication skills.

    PREFERENCES

    • Experience in comparative genome analysis, phylogenetic analysis, protein domain analysis would be an asset.

    TERMS

    The Sanger Institute operates at the forefront of genomics, sequencing and analyzing a wide range of genomes from single-cell pathogens to higher vertebrates. The Institute's emphasis is on genomes relevant to human medicine and welfare: from malaria causing pathogens to the Thousand Genomes project, the Wellcome Trust Case Control Consortium and the Cancer Genome project. The Institute recently received significant funding from the US NIH to expand the ENCyclopedia Of DNA Elements (ENCODE) project to the entire human genome. In its pilot phase the ENCODE project yielded provocative new insights into the functional elements and their organization within the human genome.

    This position is for a fixed term until Sept 2012. Please load a covering letter describing how your previous experiences make you a suitable candidate for this position.

    COMPENSATION

    The Institute has excellent purpose built facilities on the Genome Campus, Hinxton on the outskirts of Cambridge. We offer a comprehensive range of benefits including a final salary pension scheme and excellent on-site facilities. Further details can be found on our website https://jobs.sanger.ac.uk.

    HOW TO APPLY

    To submit your CV and apply for this job please go to https://jobs.sanger.ac.uk to register and apply on line.

    Jobs at Sanger can be followed using http://twitter.com/sangerinstjobs

    DEADLINE

    The closing date for this position is 25 March 2011

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