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    Opportunity: Research Associate 4 / Scientist I (#1100765) @ Bristol-Myers Squibb--Milpitas, CA (US)
    Submitted by Jody Aikawa; posted on Tuesday, March 29, 2011


    The successful candidate will be an integral member of a core transgenic team tasked with creating new transgenic models for the BMS HuMab platform, and related transgenic models supporting preclinical research. The candidate will be involved in all aspects of transgenic mouse production, with an emphasis on embryo production and isolation, microinjection of preimplantation embryos, embryo transfers, and all husbandry and surgical skills necessary to support the transgenic process. The candidate will also participate in other aspects of the transgenic process, including transgene production and purification, genotyping, phenotypic analysis and colony management of the new transgenic strains.

    Candidate must work well in a team-oriented environment, and have the skills and experience necessary to help optimize and troubleshoot various aspects of transgenic mouse production and breeding. Candidate will be responsible for developing injection schedules and timetables associated with projects, and will assist others in planning and technical procedures. Candidate will be occasionally needed for weekend or after-hours procedures. Candidate must be proficient in the use of computer databases, and be competent in capturing, organizing and presenting their data on a regular basis.


    • A Bachelors degree in a relevant scientific discipline and 4-6 years of related postgraduate laboratory experience, or an MS in relevant scientific discipline and at least 2 years of related postgraduate laboratory experience. Non-degree holders would require at least 10 years of related laboratory experience with at least 70 percent of solid experience in all the requirements.
    • As an essential member of the BMS core group responsible for mouse transgenic models, the candidate must be practiced and proficient in the following: mouse embryo transfer (infundibular and uterine), mouse embryo collection and handling, pronuclear and blastocyst injection, and all surgical procedures related to the transgenic process.
    • Additionally, the candidate will also have experience in mouse colony management and molecular biological techniques associated with transgene isolation and screening.
    • Must have 2+ years of relevant experience in a mouse transgenics lab, directly handling mice or rodents, duties primarily revolve around creation of transgenic models.
    • Must have 2+ years experience in production, isolation, or genotyping of transgene constructs.
    • Must have computer skills necessary to enter and access comprehensive mouse database.


    • Experience with ES cell culturing, morula and/or tetraploid aggregations a plus.
    • AALAS certification or training is desirable.


    Milpitas, CA


    To apply for this position, copy/paste the following URL into your browser:[...]8410d


    April 29, 2011

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