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BACKGROUND

We are seeking an ambitious scientist to lead an independent research programme within the MRC Functional Genomics Unit (FGU). Using computational and/or experimental approaches you will meet the promise provided by recent sequencing technologies to identify alleles, genes and pathways contributing to common disease. The FGU's mission is to develop methods that interrogate the genome which, when combined with mouse and fly genetics, allow the identification of disease mechanisms, particularly for neurological disorders. The Unit is embedded within the Department of Physiology, Anatomy and Genetics at the University of Oxford.

RESPONSIBILITIES

Your genomics research programme might focus on one or more of the following areas, closely linked with experimental science within the FGU: transcriptional regulation, epigenetics, transcriptomics, noncoding RNAs, imprinting, disease susceptibility, structural variation, and evolution. Your research programme will take advantage of excellent computational and laboratory facilities in the recently opened Henry Wellcome Building of Gene Function. MRC core funding for at least one post-doctoral post is available and you will also apply to other funding agencies and attract graduate students from the FGU graduate programme. There are substantial opportunities to forge links within the Department, as well as more widely within the clinical departments allowing the opportunity for translational research.

REQUIREMENTS

PhD / DPhil in the fields of computational biology, genetics or genomics
Evidence of ability to carry out successfully an independent research programme with research experience spanning multiple research fields or disciplines
International research profile and well established scientific track record – including senior author publication record
Experience in successfully mentoring PhD students and postdoctoral researchers and securing and managing independent research funding

TERMS

The appointment will be open-ended at MRC Band 2 and is subject to peer review.

LOCALE

You will work in the MRC Unit within the Department of Physiology, Anatomy and Genetics at the University of Oxford. The Functional Genomics Unit is a world-renowned centre for comparative genomics and research into neurological disorders. We offer excellent computational and laboratory facilities in the Henry Wellcome Building of Gene Function. Additional information about the Unit can be found at http://www.mrcfgu.ox.ac.uk, whilst informal enquiries can be made to Prof. Chris Ponting at chris.ponting[at]dpag.ox.ac.uk. For further information about the MRC please visit http://www.mrc.ac.uk.

COMPENSATION

Depending on experience, starting salary will be in the range GBP 44,314 to GBP 57,534 pa. Benefits will include 30 days annual leave and an excellent pension scheme.

HOW TO APPLY

Applications for this role must be made online at https://ext.ssc.rcuk.ac.uk. If you do not have internet access or experience technical difficulties, please call 01793 867003, quoting reference number IRC37702.

DEADLINE

12 January 2012. Interviews to be held 27 February 2012.

POLICY

The MRC is an Equal Opportunities Employer

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