[Next-Generation Sequencing Book]
  • [Photo] Roxanne Reyna • March 14, 2012

    BACKGROUND

    The Human Genome Sequencing Center (HGSC) at Baylor College of Medicine seeks an enthusiastic individual to work with software in a rapidly evolving research environment to support the advance of next generation sequencing technology and genomics research.

    As one of three large-scale sequencing centers funded by the National Institutes of Health, HGSC provides a unique opportunity to work with cutting-edge genomic scientists, and new clinical sequencing initiatives.

    RESPONSIBILITIES

    • Perform analysis, design, implementation, documentation and unit testing of software for the standard pipelined analysis of next generation sequencing data including large dataset integration.
    • Participate in the design, implementation, testing, and deployment of extensions of the existing production QC and analysis systems, as well as new versions of them.
    • Provide support of the existing production sequence QC and analysis systems, including the resolution of custom user and data retrieval requests.
    • Follow prescribed practices for software version control, testing, and release engineering.
    • Apply analytical skills and creativity to solve diverse and challenging problems.
    • Communicate regularly with customers and supervisory staff about plans, designs and progress.
    • Ability to prioritize, organize and delegate various tasks on projects.
    • Present technical and analytical status in weekly meetings and contribute to publications.

    REQUIREMENTS

    • Required: Bachelor's degree in Computer Science or Biological Sciences. Preferred: Master's degree in domain informatics (computational biology, computational chemistry, bioinformatics, clinical informatics).
    • Required: Three years of experience in bioinformatics software development or a Master's degree in Computer Science or Biological Sciences and one year of domain-relevant science experience in biology, genetics, physics, statistics, or health sciences.
    • Strong computational/programming skills; including extensive experience with the following: UNIX environment; Clustered computing: (MOAB/Torque, PBS, or LSF familiarity) and parallelization in a cluster environment; Next-generation analysis toolkits (PICARD, GATK, Samtools, etc.). Advanced skills in two programming languages including Ruby, Java, or Perl.

    PREFERENCES

    • Familiarity with multi-processing/threading methods, and workflow/pipeline tools
    • Experience producing code documentation
    • Exposure to statistical analysis of large datasets
    • Experience integrating software with LIMS
    • Ability to handle and prioritize multiple software requirements
    • Ability to function independently and solve technically complex problems

    HOW TO APPLY

    Please apply to 216090JC at http://www.medschooljobs.org.

    POLICY

    Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

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