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BACKGROUND

TCAG, The Centre for Applied Genomics at The Hospital for Sick Children, is one of the leading genomics centres in the world. The TCAG informatics facility is involved in computationally challenging problems such as de-novo genome assembly, identification of potentially pathologic single nucleotide variants utilizing exome or whole-genome re-sequencing and copy number variant detection. TCAG also supports the Database of Genomic Variants (DGV), the major copy number variation database. The Hospital for Sick Children is one of the leading paediatric health care centres in the world with an international reputation for excellence in health care, research, and teaching.

RESPONSIBILITIES

We are seeking a highly motivated bioinformatics analyst to run and extend analysis pipelines for human/mammalian NGS (next generation sequencing) data, with a specific focus on variant detection in exome and whole genome resequencing applications. The position will report directly to the informatics core facility manager and will involve close interactions with other informatics facility members, graduate students and post-doctoral fellows in the group.

REQUIREMENTS

The candidate will have a M.Sc. or equivalent degree in Bioinformatics, Computational Biology, Computer Science, Biomedical Engineering or related fields. Previous experience with sequence data analysis, solid knowledge of scripting languages (Perl, Python, R or Ruby), SQL and Unix OS are required. Excellent communication and team work skills are also required. Strong preference will be given to Canadian citizens, permanent residents as well as graduates of a Canadian institution eligible for a post-graduation work permit.

PREFERENCES

Previous experience with NGS data is a strong plus, preferable if related to variant detection in exome/whole genome variant detection.

TERMS

Fixed-term, 2 year contract, with the possibility of extension. TCAG is strongly committed to provide continuative funding for bioinformatics personnel with a good performance record.

LOCALE

The work will be conducted at the TCAG/The Hospital for Sick Children, Toronto. Toronto is a major international centre of genomics, proteomics and systems biology research; there will ample opportunity for professional development through research seminars, workshops and research in progress meetings.

COMPENSATION

Salary is commensurate with education and qualifications.

HOW TO APPLY

Interested applicants must submit a curriculum vitae (including three reference contacts) and the completed Application for Employment form via email to ex.research[at]sickkids.ca quoting file number GGB1116-ME in the subject line of your e-mail. SickKids Application for Employment Form can be found on the SickKids website (http://www.sickkids.ca). Only applications submitted through ex.research[at]sickkids.ca will be considered. Please note that resumes must be sent in PDF or Word format only. General inquiries sent to this e-mail address will not be answered. Only those applicants selected for an interview will be contacted.

DEADLINE

Open until position is filled.

POLICY

SickKids is strongly committed to diversity within its community and welcomes application from visible minority group members, women, Aboriginal persons, members of sexual minority groups, persons with disabilities and others who may contribute diversity within our organization. SickKids is also committed to providing accommodations to persons with disabilities in our recruitment process.

Discussion forums: Opportunity: NGS (Next generation Sequencing) Data Analyst (#GGB1116-ME) @ The Hospital for Sick Children--Toronto, ON, Canada

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