[Next-Generation Sequencing Book]
  • [Photo] Chris Smith • April 12, 2012

    BACKGROUND

    NGM Biopharmaceuticals, Inc. is an early-stage biotech dedicated to discovering the next generation of medicines for the treatment of metabolic diseases. Our experienced scientific team has joined forces with an impressive group of industry professionals, Nobel Laureates, and other distinguished researchers to form a brand new company where innovation and cutting edge science will provide the foundation for a robust drug discovery engine.

    Our expansion has created the need for a new position with us.

    RESPONSIBILITIES

    We are currently looking for a creative and highly motivated Bioinformaticist to contribute his/her superb technical skills and scientific expertise towards the discovery of transformational new therapeutics. The successful candidate will take a lead role in data mining, data visualization, statistical analysis, experimental design and database development to support genomics-based discovery efforts at NGM. This individual will be responsible for developing and managing a computational genomics platform and the analysis of experimental data, enabling NGM's research objectives with a focus on the identification of therapeutic targets and biomarkers associated with the resolution of diabetes following gastric bypass surgery. As a member of a multidisciplinary research team, the bioinformaticist will:
    • Develop, in collaboration with researchers, an integrated analysis platform for genomics-based comparisons.
    • Design and apply bioinformatics algorithms including machine learning, dynamic programming or graphic algorithms and feature selection and pattern recognition algorithms to find predictive patterns and enable biomarker discoveries.
    • Develop and implement standardized protocols for data analysis and quality control of genomics experiments, including background correction algorithms, data normalization, principal component analysis, statistical inference methods, and clustering algorithms.
    • Provide statistical and computational tools for genomic analysis and measurement of RNA expression.
    • Manipulate publicly accessible, commercial, or proprietary genomic, proteomic, or post-genomic databases.
    • Design and apply computer systems and databases used to organize and analyze large amounts of biological data.
    • Oversee and provide technical guidance to enable the design, development and maintenance of a biological database integrating data from diverse information sources.

    REQUIREMENTS

    Applicants must have a Ph.D. degree in bioinformatics, computer science, or life sciences-related field and 5+ years of relevant experience in computational biology, including algorithm development, quality control data analysis and hands-on data analysis. Knowledge of genomics and proteomics software / platforms and sequence databases is a prerequisite for this position. Experience in designing, developing and accessing software for genomics-based methods, including integration with RNA and protein databases, is desirable. Strong communication skills, and the ability to work effectively as part of a research team, are essential.

    HOW TO APPLY

    Applicants should direct inquiries, along with current CVs, regarding this posting to the following email address: bioinform[at]ngmbio.com. Please indicate your interest in the Bioinform2012‐01 position.

Discussion forums: Opportunity: BIOINFORMATICIST (#Bioinform2012‐01) @ NGM Biopharmaceuticals, Inc.--South San Francisco, CA (US)

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