[Next-Generation Sequencing Book]
  • [Photo] Chaolin Zhang • November 29, 2012

    BACKGROUND

    Dr. Chaolin Zhang laboratory at Columbia University Medical Center is seeking Postdoctoral fellows to conduct NIH-funded studies of RNA regulatory circuitry in the mammalian nervous system. The Zhang laboratory is a newly formed lab in the Department of Biochemistry and Molecular Biophysics (BMB), the Columbia Initiative in Systems Biology (CISB), the Center for Motor Neuron Biology and Disease (MNC), and the Columbia Stem Cell Initiative (CSCI). Using a combination of biochemistry, molecular biology, and high-throughput quantitative and integrative approaches, the Zhang Laboratory studies how proteins and RNA interact to form regulatory networks in the nervous system at the mechanistic and systems level. These networks are increasingly shown to be essential to understand the mammalian complexity manifested in evolutionary-developmental (evo-devo) processes and in neuronal disorders. More information about the Zhang laboratory can be found at http://zhanglab.c2b2.columbia.edu.

    REQUIREMENTS

    • A Ph.D. degree in Computational or Systems Biology, Bioinformatics, Computational Genomics, Computer Sciences or Physics, or related fields
    • A genuine interest in solving complex biological problems using quantitative approaches
    • Strong background in statistical modeling and machine learning
    • Solid programing skills using C or C++ and one scripting language
    • Extensive experience in handling large-scale data, including those from next-generation sequencing, microarrays and genome annotations
    • Highly motivated and ability to work independently as well as to collaborate in a group setting
    • Excellent written and verbal communication skills
    • A minimal of one first-author paper published in related peer-reviewed journals

    PREFERENCES

    • Previous experience working with protein-DNA/RNA interaction data and RNA splicing
    • Previous experience on comparative genomics
    • Basic knowledge of molecular biology and neuroscience

    TERMS

    A one-year term appointment with yearly renewal based upon satisfactory job performance

    LOCALE

    New York, NY

    COMPENSATION

    NIH and University Guideline

    HOW TO APPLY

    Send the following information to Dr. Chaolin Zhang at cz2294[at]columbia.edu by E-mail.
    1) Curriculum Vitae
    2) A description of previous research experience and future plan
    3) List of three references

    DEADLINE

    The positions are open until filled, but preferably by Jan 31, 2012.

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