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``Four years after researchers in Scotland startled the world by announcing that they had cloned a sheep named Dolly, scientists say evidence is mounting that creating healthy animals through cloning is more difficult than they had expected.
``The clones that have been produced, they say, often have problems severe enough - developmental delays, heart defects, lung problems and malfunctioning immune systems - to give pause to anyone thinking of cloning a human being. In one example that seems like science fiction come true, some cloned mice that appeared normal suddenly, as young adults, grew grotesquely fat.
``It is not that one particular thing goes wrong or one specific aspect of development goes awry, researchers say. Rather, leading cloning experts and developmental biologists said in recent interviews, the cloning process seems to create random errors in the expression of individual genes. Those errors can produce any number of unpredictable problems, at any time in life.''
Full story (free registration required):
http://www.nytimes.com/2001/03/25/world/25CLON.html
Reference by Slashdot.org.
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Discussion forums: NYTimes: Researchers Find Big Risk of Defect in Cloning Animals
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