[Next-Generation Sequencing Book]
  • [Photo] Mike Wilmarth • October 23, 2003

    BACKGROUND

    I am assisting to recruit Molecular Modeler for a client's Drug Discovery Applications Group in New York City. Here is more information:

    This client is a technology leader specializing in computational methods for drug discovery and development. Benefits include medical, dental, 401(k), flexible spending account, 3+ weeks vacation, stock options, and tuition reimbursement. Visa sponsorship and/or relocation are available.

    The successful candidate will become part of a multidisciplinary drug discovery team working on both in-house efforts to improve and apply drug discovery methodologies and on collaborative projects with pharmaceutical/biotechnology partners.

    DESCRIPTION:
    • Actively participate in Drug Discovery Applications Group projects
    • Apply drug discovery software and perform analysis of the results
    • Effectively communicate results to other members of the Group
    • Work closely with the Development Team to test and improve Drug Discovery technologies

    REQUIREMENTS

    • Ph.D. in computational chemistry, organic chemistry, or biochemistry
    • Computational experience in at least 1 of the following areas: molecular modeling, structure-based drug design, virtual ligand screening, computationally-driven lead optimization, ligand-based design, or homology modeling
    • Excellent verbal and written communication skills
    • Ability to work independently
    SKILLS:
    • Programming skills: Perl script writing, in particular
    • Experience with chemical databases

    HOW TO APPLY

    For consideration, please send CV including publications, thesis topic, and advisor to resumes[at]workwondersstaffing.net

    This client is an Equal Opportunity Employer.

    [Please help Bioinformatics.Org: Reference us when replying to this announcement.]

Discussion forums: Opportunity: MOLECULAR MODELER--New York City, NY (US)

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Molecular modeller application
Submitted by Nobody ; posted on Tuesday, December 2, 2003
Dear sir/madam I am a postgraduate in Biotechnology with pharmacy as my graduation . I have done an advanced diploma course in Bioinformatics , with project in Molecular modeling dept,from Indian Institute of Chemical Technology,Hyderabad , India. My advisor is Dr.G.N.Sastry ,Head Molecular Modeling group IICT,HYDERABAD , AP , INDIA.I am keen in working in the area of Molecular Modeling and Drug discovery. My mail ID is vijaya_ls@indiatimes.com or vijaya_ls@rediffmail.com. I am sending my resume for your kind perusal. Thankyou yours sincerely S.Vijayalakshmi C.Vijaya Lakshmi S.VijayaLakshmi Address (Permanent) : c/o Prof.C.Varada chary, H.No.2-1-10/1, Saraswaticolony, Streetno.3 , uppal , Hyderabad , Andhra Pradesh - 500039 Address (Current) : c/o Dr.T.R.K.Chetty,H.No.16-52/1 , Prashant Nagar , Behind Little Flower Junior college,Uppal, Hyderabad , Andhra Pradesh - 500039 E-mail : vijaya_ls@rediffmail.com , vijaya_ls@indiatimes.com Tel No.(Res) : 040-27208581 , 040-27204301 -OBJECTIVE : I aim to excel and significantly contribute in the fields of Molecular Modelling and Drug Designing . - SUMMARY: Hard working , sincere and committed Post graduate Biotechnologist from BITS,Pilani and Graduate in Pharmacy with excellent academic record ,Rank holder through out the career. Thoroughly trained in Advanced Bioinformatics , jointly organised by IICT , Hyderabad and CDAC , Pune. Good Software knowledge and experience in Molecular Modeling and Sequence analysis tools. - PERSONAL PROFILE: - Sex : Female - Nationality : Indian - Marital Status : Married - Date of Birth : 28 feb 1970 - Languages : Telugu,English,Hindi - Hobbies : Reading, Writing, music, sketching - EDUCATION: # 2003: Advanced course in Bioinformatics , IICT and CDAC , Hyderabad # 1995:M.E Biotechnology ,Birla Institute of Technology,Pilani,Rajasthan # 1992: Bachelor of Pharmacy ,Kakatiya University College of Pharmaceutical Sciences,Warangal # 1988: Intermediate,Pingle College for Women,Warangal # 1985: Secondary School Certificate, Kakatiya High School, Warangal. - RESEARCH TRAINING: # Project trainee: 2003oct-2003nov, Department of Molecular Modeling, Indian Institute of Chemical Technology,Hyderabad. # Project trainee: 1995 jun-dec,Department of Fermentation technology , Central Drug Research Institute,Lucknow,UttarPradesh. -PROJECTS : # Title - Quantitative Structure Activity Relationship Studies of Non-Sulphonyl COX-2 Inhibitors Abstract : A systematic analysis of Anti-asthmatic drugs and QSAR studies are reported using MOE and CERIUS 2 Softwares. The G/PLS method in Cerius2 and PLS method in MOE were employed to generate the QSAR equations. # Title - Biotransformation of Industrially important steroidal precursors Abstract : The project work deals with Biotransformation of raw materials like 16-Dehydropregnenolone acetate, progesterone,and ethyl secodione by C.lunata , P.farinosa , A.ochraceus , A.simplex in Total cell cultures , suspended mycelium cultures, immobilized cell culture methods. The transformation experiments Carried out are 11 beta-hydroxylation ,11 alpha-hydroxylation, and 17 beta-oxidoreduction - WORK EXPERIENCE: #2001: Lecturer in BioTechnology ,AroraDegreeCollege,Chikkadpally,Hyderabad #1999: Lecturer in Pharmacy , Venkateswara College of Pharmacy , Madhapur,Hyderabad #1997: Technical officer , Jupiter Biosciences ,West Marredpally , Hyderabad - FIELDS OF INTEREST: # Molecular Modelling and Drug Designing # Application of Computational Chemistry Methods to Pharmaceutical & Biological Problems # Homology-Based Modeling of Proteins (Receptor & Enzymes) # Molecular Basis of Drug-Receptor/Enzyme Interactions # Agonist/Antagonist Design for Enzymes (Rational Drug Design) # Computational Molecular Biology - TECHNICAL QUALIFICATIONS: - Instrumentation Techniques: # UV/Visible Spectrophotometry # Chromatography(TLC , HPLC , Paper chromatography) # Colorimetry # Fluorimetry # Polarimetry # NMR # X-Ray Crystallography - Biotechnology and MolecularBiology Techniques: # Isolation and purification of Plasmid DNA # Gel electrophoresis Techniques # Plant cell and tissue culture techniques # Aseptic culture preparation # Preparation of Suspension Cultures # Shake flask culture techniques # Immobilized cell culture techniques - SOFTWARE SKILLS: # Operating systems : LINUX,WINDOWS 98 , Windows 2000 # Programming Languages : C-Language ,Perl , SQL # Databases : Oracle 9 # Familiar with Silicon graphics Workstations, Related Software - BIOINFORMATICS SOFTWARES: # SYBYL # INSIGHT II # MOPAC # PC-MODEL # WINMOPAC # RASMOL # BLAST # FASTA # SWISS-PDB VIEWER #MOE #PCM6 # ISIS Draw # Cerius2 # Rasmolv2 # Chemdraw - BIOINFORMATICS SKILLS: # Semi-Empirical Quantum Mechanical Models. # Molecular Mechanic/Dynamic Methods and Simulations. # Conformational Analysis Techniques. # Alignment, Prediction and Homology Based Modeling of Proteins. # Docking and Quantitative Structure-Activity Relationships # Databanks - SEMINARS and WORKSHOPS: # 2001- Participant of Teachers Workshop in Biotechnology , Osmania University , Hyderabad # 1995 - Project leader for the non-working model of 'G' proteins and Animated model for Antisense RNA at APOGEE (Educational exhibition ) , BITS , Pilani -AWARDS and ACHIEVEMENTS: # Topper in M.E (Biotechnology) # 6th Rank Holder in B.Pharmacy # Appreciation certificate for the essay competition ' Role of Pharmacists in the Stability of Pharmaceuticals ' from B.V.Patel Educational Trust -REFERENCES: # Dr.U.S.N. Murty Deputy Director & Head Biology Division Indian Institute of Chemical Technology Hyderabad - 500 007 Email : usnmurty@iict.ap.nic.in murty_usn@yahoo.com TEL : 040-27193134 # Dr.G.Narahari Sastry Scientist , Molecular Modelling Group Indian Institute of Chemical Technology Hyderabad-500 007 TEL : 040-27176418 , Mobile : 9849134401

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Molecular modeller application
Submitted by Nobody ; posted on Tuesday, December 2, 2003
Dear sir/madam I am a postgraduate in Biotechnology with pharmacy as my graduation . I have done an advanced diploma course in Bioinformatics , with project in Molecular modeling dept,from Indian Institute of Chemical Technology,Hyderabad , India. My advisor is Dr.G.N.Sastry ,Head Molecular Modeling group IICT,HYDERABAD , AP , INDIA.I am keen in working in the area of Molecular Modeling and Drug discovery. My mail ID is vijaya_ls@indiatimes.com or vijaya_ls@rediffmail.com. I am sending my resume for your kind perusal. Thankyou yours sincerely S.Vijayalakshmi C.Vijaya Lakshmi S.VijayaLakshmi Address (Permanent) : c/o Prof.C.Varada chary, H.No.2-1-10/1, Saraswaticolony, Streetno.3 , uppal , Hyderabad , Andhra Pradesh - 500039 Address (Current) : c/o Dr.T.R.K.Chetty,H.No.16-52/1 , Prashant Nagar , Behind Little Flower Junior college,Uppal, Hyderabad , Andhra Pradesh - 500039 E-mail : vijaya_ls@rediffmail.com , vijaya_ls@indiatimes.com Tel No.(Res) : 040-27208581 , 040-27204301 -OBJECTIVE : I aim to excel and significantly contribute in the fields of Molecular Modelling and Drug Designing . - SUMMARY: Hard working , sincere and committed Post graduate Biotechnologist from BITS,Pilani and Graduate in Pharmacy with excellent academic record ,Rank holder through out the career. Thoroughly trained in Advanced Bioinformatics , jointly organised by IICT , Hyderabad and CDAC , Pune. Good Software knowledge and experience in Molecular Modeling and Sequence analysis tools. - PERSONAL PROFILE: - Sex : Female - Nationality : Indian - Marital Status : Married - Date of Birth : 28 feb 1970 - Languages : Telugu,English,Hindi - Hobbies : Reading, Writing, music, sketching - EDUCATION: # 2003: Advanced course in Bioinformatics , IICT and CDAC , Hyderabad # 1995:M.E Biotechnology ,Birla Institute of Technology,Pilani,Rajasthan # 1992: Bachelor of Pharmacy ,Kakatiya University College of Pharmaceutical Sciences,Warangal # 1988: Intermediate,Pingle College for Women,Warangal # 1985: Secondary School Certificate, Kakatiya High School, Warangal. - RESEARCH TRAINING: # Project trainee: 2003oct-2003nov, Department of Molecular Modeling, Indian Institute of Chemical Technology,Hyderabad. # Project trainee: 1995 jun-dec,Department of Fermentation technology , Central Drug Research Institute,Lucknow,UttarPradesh. -PROJECTS : # Title - Quantitative Structure Activity Relationship Studies of Non-Sulphonyl COX-2 Inhibitors Abstract : A systematic analysis of Anti-asthmatic drugs and QSAR studies are reported using MOE and CERIUS 2 Softwares. The G/PLS method in Cerius2 and PLS method in MOE were employed to generate the QSAR equations. # Title - Biotransformation of Industrially important steroidal precursors Abstract : The project work deals with Biotransformation of raw materials like 16-Dehydropregnenolone acetate, progesterone,and ethyl secodione by C.lunata , P.farinosa , A.ochraceus , A.simplex in Total cell cultures , suspended mycelium cultures, immobilized cell culture methods. The transformation experiments Carried out are 11 beta-hydroxylation ,11 alpha-hydroxylation, and 17 beta-oxidoreduction - WORK EXPERIENCE: #2001: Lecturer in BioTechnology ,AroraDegreeCollege,Chikkadpally,Hyderabad #1999: Lecturer in Pharmacy , Venkateswara College of Pharmacy , Madhapur,Hyderabad #1997: Technical officer , Jupiter Biosciences ,West Marredpally , Hyderabad - FIELDS OF INTEREST: # Molecular Modelling and Drug Designing # Application of Computational Chemistry Methods to Pharmaceutical & Biological Problems # Homology-Based Modeling of Proteins (Receptor & Enzymes) # Molecular Basis of Drug-Receptor/Enzyme Interactions # Agonist/Antagonist Design for Enzymes (Rational Drug Design) # Computational Molecular Biology - TECHNICAL QUALIFICATIONS: - Instrumentation Techniques: # UV/Visible Spectrophotometry # Chromatography(TLC , HPLC , Paper chromatography) # Colorimetry # Fluorimetry # Polarimetry # NMR # X-Ray Crystallography - Biotechnology and MolecularBiology Techniques: # Isolation and purification of Plasmid DNA # Gel electrophoresis Techniques # Plant cell and tissue culture techniques # Aseptic culture preparation # Preparation of Suspension Cultures # Shake flask culture techniques # Immobilized cell culture techniques - SOFTWARE SKILLS: # Operating systems : LINUX,WINDOWS 98 , Windows 2000 # Programming Languages : C-Language ,Perl , SQL # Databases : Oracle 9 # Familiar with Silicon graphics Workstations, Related Software - BIOINFORMATICS SOFTWARES: # SYBYL # INSIGHT II # MOPAC # PC-MODEL # WINMOPAC # RASMOL # BLAST # FASTA # SWISS-PDB VIEWER #MOE #PCM6 # ISIS Draw # Cerius2 # Rasmolv2 # Chemdraw - BIOINFORMATICS SKILLS: # Semi-Empirical Quantum Mechanical Models. # Molecular Mechanic/Dynamic Methods and Simulations. # Conformational Analysis Techniques. # Alignment, Prediction and Homology Based Modeling of Proteins. # Docking and Quantitative Structure-Activity Relationships # Databanks - SEMINARS and WORKSHOPS: # 2001- Participant of Teachers Workshop in Biotechnology , Osmania University , Hyderabad # 1995 - Project leader for the non-working model of 'G' proteins and Animated model for Antisense RNA at APOGEE (Educational exhibition ) , BITS , Pilani -AWARDS and ACHIEVEMENTS: # Topper in M.E (Biotechnology) # 6th Rank Holder in B.Pharmacy # Appreciation certificate for the essay competition ' Role of Pharmacists in the Stability of Pharmaceuticals ' from B.V.Patel Educational Trust -REFERENCES: # Dr.U.S.N. Murty Deputy Director & Head Biology Division Indian Institute of Chemical Technology Hyderabad - 500 007 Email : usnmurty@iict.ap.nic.in murty_usn@yahoo.com TEL : 040-27193134 # Dr.G.Narahari Sastry Scientist , Molecular Modelling Group Indian Institute of Chemical Technology Hyderabad-500 007 TEL : 040-27176418 , Mobile : 9849134401

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