[Next-Generation Sequencing Book]
  • [Photo] Kesavan • October 7, 2002
    Dr. Reddy's Laboratories Limited is an emerging global pharmaceutical company focused on creating and delivering innovative solutions that enable people to lead healthier lives. Our R&D unit Discovery Research is poised to become a world-class resource for the discovery and development of excellent and innovative therapies. We have four new Chemical Entities in clinical development and several are in pipeline. Our Molecular Modeling and Drug Design group is currently looking for candidates for the following positions based at Hyderabad, India.

    Scientist / Sr. Scientist - Molecular Modeling and Drug Design

    We are looking for a highly motivated and creative person for the position of Scientist/Sr. Scientist in Molecular Modeling & Drug Design based at the state-of-the-art research facility in Hyderabad.

    Job responsibilities include:
    • Building homology models for novel targets and locating potential ligand binding sites.
    • Performing structure-based and ligand-based drug design, developing methods for fast and reliable calculation of ligand binding energies.
    • Pharmacophore elucidation, constructing virtual combinatorial screening libraries, optimization of physicochemical and ADME/DMPK properties and related activities.
    The ideal candidate shall have a Ph.D. in Computational Chemistry/Biology/Biophysics, or a related field with experience in using molecular modeling software.

    A good working knowledge of medicinal/organic chemistry would be an added advantage. Knowledge of VB, FORTRAN, C++ and Unix/Linux and expertise with relational and structural databases is also highly desirable.

    Position and remuneration will be commensurate with qualification and experience. Dr. Reddy's provides a stimulating work environment and offers excellent opportunities for growth.

    For confidential consideration, please send your resume within 15 days indicating two references to the Human Resource Group at the address hereunder. Please mention the relevant position as the subject of the Email or super scribe the same on the envelope.

    Human Resource Department
    Dr. Reddy's Laboratories Limited
    Discovery Research
    Bollaram Road, Miyapur
    Hyderabad 500 050.A.P., India

    Tel: 91 40 304 5439; Fax: 91 40 304 5438; Email: kunni[at]drreddys.com

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1+exp in molecular modelling feild.
Submitted by awantika shrivastava ; posted on Thursday, December 27, 2007
Dear sir, Greetings!!!! Reference to the above mentioned subject I am keen on working in your organization in the above mentioned post. If given opportunity to work in your organization I will do my best to get the best results and name to the company. Awaiting reply at the earliest Thanks & regards Awantika shrivastava Awantika shrivastava Sri sathya sai working womens hostel, Near Bhaskara hospital, Ameerpet, Hyderabad, 500018 awantika31@hotmail.com Mobile no-9885536704, 9334250844 1.Objective Masters in bioinformatics with sound technical skills and good communication skills seeking an innovative and challenging opportunity that would facilitate mutual benefit of my employer and myself. 2.HIGHLIGHTS OF QUALIFICATION Ø Experienced in COMPUTER AIDED DRUG DESIGINING and working with senior scientists. Ø Highly Motivated, goal Oriented professional; a decision maker skilled in implementing new ideas. Ø A team player with strong communication, presentation, interpersonal and research skills 3.PROFESSIONAL EXPERIENCE 1. COMPANY NAME- NATCO PHARMA COMPANY (MARCH-2007 to present) Ø JOB PROFILE- Application Bioinformatics CHEMIST. Ø Description- v . Work with Senior Scientist in designing new drug molecule against diseases like cancer. v . Determine and interpret the results getting by several molecular modelling SOFTWARES like DS- 1.7, Glide. v . Suggestion in designing the new drug molecule. 2. COMPANY NAME- ACCELRYS SOFTAWRE PVT LTD- (INDIA) Ø JOB PROFILE- Research Associate. (Aug-2006 to Jan-2007) Ø Description- v Work with Senior Scientist in project related to Drug Metabolizing enzyme CYP-450 3. SKILLS Ø IT----- v Programming Languages: C, C++ and BIOPERL v Operating Systems: MS-DOS, Windows 9x/2000/NT, UNIX, LINUX v Databases: MS-Access and SQL Server, ORACLE 8I v Web Technologies: HTML Ø BIO –IT (bio-informatics) v Docking- Autodock, Hex 4.2,Ligandfit, discovery studio (1.6), Affinity (INSIGHT II), Schrodinger-glide v Protein modeling- Modeller, swisspdv, homology (insight- II) v Denovo ligand design-Ludi v 3-D structure Visualization-pymol, rasmol, molscript, swisspdv v Online tools- BLAST, FASTA (search tools) v CLustalw- (sequence alignment) v SOPMA- (secondary structure prediction) v MOLCONVERTER- (Molecule file conversion) v Construction or carbohydrates proteins, peptides etc- BIOPOLYMER v QSAR- TSAR v Chemsketch, isis draw Ø MOL-BIO v Cell culture techniques: Cell isolations, Cell transfections, sub culturing, freezing cells, resurrecting frozen cells, maintaining cells under lab conditions etc. v Sterilizations technique-centrifugation, Chromatography, Electrophesis, PCR, MARKER STUDY v Ligation method DNA isolation methodologies, Isolation of plasmid, reaction of amino acids &sugars. Mapmaker v SDS-PAGE, X-ray crystallography(crystal cutting and mounting of crystal) 4.Educational Qualifications Degree / Examination University/ Board College /School Year of passing Percentage / Grade M.S.C BIOINFORMATICS BERAHMPUR University MITS, ORRISSA April 2006 85%(distinction) B.S.CMICROBIOLOGY BANGALOREUniversity T.JOHN COLLEGE. April 2003 72% 5.Projects 1. Project Name :INSILICO MOLECULAR MODELLING AND DOCKING STUDIES S/W: AUTODOCK, MODELLER, MOLSCRIPT, INSIGHTII, Platform: UNIX, Place - central drug research institute (lucknow) 2.Project Name: PROTEIN LIGAND INTERACTION S/W: hex 4.2,CHEMSKETCH. Platform: Windows 2000/XP PLACE: EDUBIOTECH (Ban galore) 10.ACHIEVEMENT v University topper in Ms. (BERAHMPUR UNIVERSITY)(Distinction holder) 11.Conference Attended 1. Indo–German conference related to molecular modelling (Hyd- 2007) Declaration I declare that the above given information is true to best of my knowledge. Signature: Awantika shrivastava

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1+exp in molecular modelling feild.
Submitted by awantika shrivastava ; posted on Thursday, December 27, 2007
Dear sir, Greetings!!!! Reference to the above mentioned subject I am keen on working in your organization in the above mentioned post. If given opportunity to work in your organization I will do my best to get the best results and name to the company. Awaiting reply at the earliest Thanks & regards Awantika shrivastava Awantika shrivastava Sri sathya sai working womens hostel, Near Bhaskara hospital, Ameerpet, Hyderabad, 500018 awantika31@hotmail.com Mobile no-9885536704, 9334250844 1.Objective Masters in bioinformatics with sound technical skills and good communication skills seeking an innovative and challenging opportunity that would facilitate mutual benefit of my employer and myself. 2.HIGHLIGHTS OF QUALIFICATION Ø Experienced in COMPUTER AIDED DRUG DESIGINING and working with senior scientists. Ø Highly Motivated, goal Oriented professional; a decision maker skilled in implementing new ideas. Ø A team player with strong communication, presentation, interpersonal and research skills 3.PROFESSIONAL EXPERIENCE 1. COMPANY NAME- NATCO PHARMA COMPANY (MARCH-2007 to present) Ø JOB PROFILE- Application Bioinformatics CHEMIST. Ø Description- v . Work with Senior Scientist in designing new drug molecule against diseases like cancer. v . Determine and interpret the results getting by several molecular modelling SOFTWARES like DS- 1.7, Glide. v . Suggestion in designing the new drug molecule. 2. COMPANY NAME- ACCELRYS SOFTAWRE PVT LTD- (INDIA) Ø JOB PROFILE- Research Associate. (Aug-2006 to Jan-2007) Ø Description- v Work with Senior Scientist in project related to Drug Metabolizing enzyme CYP-450 3. SKILLS Ø IT----- v Programming Languages: C, C++ and BIOPERL v Operating Systems: MS-DOS, Windows 9x/2000/NT, UNIX, LINUX v Databases: MS-Access and SQL Server, ORACLE 8I v Web Technologies: HTML Ø BIO –IT (bio-informatics) v Docking- Autodock, Hex 4.2,Ligandfit, discovery studio (1.6), Affinity (INSIGHT II), Schrodinger-glide v Protein modeling- Modeller, swisspdv, homology (insight- II) v Denovo ligand design-Ludi v 3-D structure Visualization-pymol, rasmol, molscript, swisspdv v Online tools- BLAST, FASTA (search tools) v CLustalw- (sequence alignment) v SOPMA- (secondary structure prediction) v MOLCONVERTER- (Molecule file conversion) v Construction or carbohydrates proteins, peptides etc- BIOPOLYMER v QSAR- TSAR v Chemsketch, isis draw Ø MOL-BIO v Cell culture techniques: Cell isolations, Cell transfections, sub culturing, freezing cells, resurrecting frozen cells, maintaining cells under lab conditions etc. v Sterilizations technique-centrifugation, Chromatography, Electrophesis, PCR, MARKER STUDY v Ligation method DNA isolation methodologies, Isolation of plasmid, reaction of amino acids &sugars. Mapmaker v SDS-PAGE, X-ray crystallography(crystal cutting and mounting of crystal) 4.Educational Qualifications Degree / Examination University/ Board College /School Year of passing Percentage / Grade M.S.C BIOINFORMATICS BERAHMPUR University MITS, ORRISSA April 2006 85%(distinction) B.S.CMICROBIOLOGY BANGALOREUniversity T.JOHN COLLEGE. April 2003 72% 5.Projects 1. Project Name :INSILICO MOLECULAR MODELLING AND DOCKING STUDIES S/W: AUTODOCK, MODELLER, MOLSCRIPT, INSIGHTII, Platform: UNIX, Place - central drug research institute (lucknow) 2.Project Name: PROTEIN LIGAND INTERACTION S/W: hex 4.2,CHEMSKETCH. Platform: Windows 2000/XP PLACE: EDUBIOTECH (Ban galore) 10.ACHIEVEMENT v University topper in Ms. (BERAHMPUR UNIVERSITY)(Distinction holder) 11.Conference Attended 1. Indo–German conference related to molecular modelling (Hyd- 2007) Declaration I declare that the above given information is true to best of my knowledge. Signature: Awantika shrivastava

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