BACKGROUND:
Lonza’s Advanced Protein Technologies (Lonza-APT) is a multidisciplinary department in Cambridge-UK pioneering the application of innovative solutions to the development of biopharmaceuticals with a primary focus in addressing manufacturability, stability and aggregation. At APT we are looking for a highly motivated and talented person to lead our Computational Biology team in Cambridge, UK.

RESPONSIBILITIES:
The major responsibilities for this position include:

• Supervise other scientists within the Computational Biology Group at APT in Cambridge
• Oversee the development and application of APT’s in silico platform, expanding software functionalities in the areas of prediction of protein aggregation & stability, protein engineering, etc.
• Co-ordinate efforts with our experimentalist teams within APT (protein engineering & cell biology) in development as well as customer projects
• Co-ordinate efforts with our Bioinformatics Services sister department in Mumbai to develop new tools and knowledge bases
• Oversee the general provision of in silico services to customers, participating in presentations on technology and scientific discussions
• Participate actively in service projects and collaborations involving protein improvement and stabilisation
• Co-ordinate research activities to consolidate and enhance APT’s current platform technology

REQUIREMENTS:
Qualifications:

• Doctoral Degree (PhD) or Masters Degree (MSc) in Bioinformatics, Computational chemistry / biochemistry, or in Biological Sciences / biochemistry, with relevant experience in computational analysis of proteins or structural bioinformatics
• Significant experience in research and development, preferably in an industrial environment.

Essential Skills:

• Previous experience in supervisory roles, preferably in industry
• Good background in protein structure & structural bioinformatics
• Previous experience in protein structural modelling and molecular dynamics simulations
• Familiarity with Linux & unix platforms
• Experience in scripting and programming, particularly in Perl (desirable C++)

Desirable Skills:

• Familiarity with antibody structure and bioinformatics tools related to antibodies
• Familiarity with the use of machine learning techniques (SVM, NN, etc.) and/or statistical analysis tools (R, etc.)
• Previous experience in characterisation of protein-protein interactions and protein docking techniques.
• Experience with relational databases (SQL, etc.)
• Experience in version controlling software (CVS)

Qualities & Attitude:

• Good project management and people management skills
• A team player, able to share knowledge and manage others effectively
• Effective in co-ordinating projects, distributing tasks and organising resources according to an established plan and to prioritise work to meet tight deadlines
• Good listener, good verbal and written communication skills
• Initiative & problem-solving attitude. Positive & creative thinking
• Ability to work in a multi-disciplinary environment. Proactive communicating with collaborators and customers
• Good organisational skills
• Flexibility
• Attention to quality

TERMS:
Permanent, Full Time, Supervisory role

LOCALE:
Advanced Protein Technologies Department, Cambridge, United Kingdom

COMPENSATION:
According to candidate's merit

HOW TO APPLY:
If you are interested in this opportunity please visit our website (http://www.lonza.com) and apply online via our E-recruiment portal: http://www.lonza.com/group/en/company/c1/s_a/Sa1.html

ARTICLE: Position Ref #51261-01

DEADLINE: May 22, 2009

ABOUT US:
Lonza is one of the world's leading suppliers to the pharmaceutical, healthcare and life science industries. Its products and services span its customers’ needs from research to final product manufacture. Lonza is the global leader in the production and support of active pharmaceutical ingredients both chemically as well as biotechnologically. Lonza is a leader in cell-based research, endotoxin detection and cell therapy manufacturing. Lonza is also a leading provider of value chemical and biotech ingredients to the nutrition, hygiene, preservation, agro and personal care markets. Lonza is headquartered in Basel, Switzerland and is listed on the SIX Swiss Exchange. In 2008, Lonza had sales of approximately CHF 3 billion. Further information can be found on our website http://www.lonza.com.