Yes, Microsoft developed C#, BUT it's an ECMA standard, so you are free to port it to Linux, for example. And that's exactly what Miguel de Icaza did with the Mono Project (www.go-mono.com). The conclusion: C# is cross plattform! And the .NET Framework is a great application plattform with rich functionality. So my opinion is, it's good for Linux to have such an API! Concerning this project, I'll find it very interesting and a good idea. This will bring Bioinformatic to thousands of (Windows-)Developer or vice versa. So, good luck!