Basic Information
Gene ID 100342616
Gene Name SMAD5
Full Name Uncharacterized protein
Organism Oryctolagus cuniculus [9986]

Cross Reference
UniProt G1SMU6 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOCUP00000004269 Gene3D G3DSA:2.60.200.10 IPR017855 263 465 6.50e-97 SMAD domain-like
ENSOCUP00000004269 Gene3D G3DSA:3.90.520.10 IPR013019 5 144 8.60e-62 MAD homology, MH1
ENSOCUP00000004269 PANTHER PTHR13703 IPR013790 1 465 0.00e-00 Dwarfin
ENSOCUP00000004269 Pfam PF03165 IPR003619 32 132 4.80e-42 MAD homology 1, Dwarfin-type
ENSOCUP00000004269 Pfam PF03166 IPR001132 266 442 7.40e-78 SMAD domain, Dwarfin-type
ENSOCUP00000004269 ProSiteProfiles PS51075 IPR013019 13 137 0.00e-00 MAD homology, MH1
ENSOCUP00000004269 ProSiteProfiles PS51076 IPR001132 271 465 0.00e-00 SMAD domain, Dwarfin-type
ENSOCUP00000004269 SMART SM00523 IPR003619 26 135 4.80e-71 MAD homology 1, Dwarfin-type
ENSOCUP00000004269 SMART SM00524 IPR001132 269 441 2.50e-108 SMAD domain, Dwarfin-type
ENSOCUP00000004269 SUPERFAMILY SSF49879 IPR008984 232 456 0.00e-00 SMAD/FHA domain
ENSOCUP00000004269 SUPERFAMILY SSF56366 IPR013019 14 132 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOCUP00000004269 PF03166 0 MH2 MH2 domain
ENSOCUP00000004269 PF03165 2.29953e-42 MH1 MH1 domain
ENSOCUP00000004269 PF10401 1.1e-06 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOCUP00000004269 GO:0001657 biological_process ureteric bud development
ENSOCUP00000004269 GO:0002051 biological_process osteoblast fate commitment
ENSOCUP00000004269 GO:0006351 biological_process transcription, DNA-templated
ENSOCUP00000004269 GO:0006468 biological_process protein phosphorylation
ENSOCUP00000004269 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
ENSOCUP00000004269 GO:0030509 biological_process BMP signaling pathway
ENSOCUP00000004269 GO:0045669 biological_process positive regulation of osteoblast differentiation
ENSOCUP00000004269 GO:0051216 biological_process cartilage development
ENSOCUP00000004269 GO:0060348 biological_process bone development
ENSOCUP00000004269 GO:0071773 biological_process cellular response to BMP stimulus
ENSOCUP00000004269 GO:1901522 biological_process positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
ENSOCUP00000004269 GO:0005634 cellular_component nucleus
ENSOCUP00000004269 GO:0005667 cellular_component transcription factor complex
ENSOCUP00000004269 GO:0005737 cellular_component cytoplasm
ENSOCUP00000004269 GO:0000979 molecular_function RNA polymerase II core promoter sequence-specific DNA binding
ENSOCUP00000004269 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSOCUP00000004269 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100011974 9258 Ornithorhynchus anatinus 100089852
7425 Nasonia vitripennis 100116381 7029 Acyrthosiphon pisum 100167170
6087 Hydra magnipapillata 100211577 10224 Saccoglossus kowalevskii 100303484
9685 Felis catus 101081602 9913 Bos taurus 768050
7719 Ciona intestinalis 778756 9483 Callithrix jacchus ENSCJAG00000005968
9361 Dasypus novemcinctus ENSDNOG00000006004 9978 Ochotona princeps ENSOPRG00000010102
132908 Pteropus vampyrus ENSPVAG00000016214 9739 Tursiops truncatus ENSTTRG00000016274
30538 Vicugna pacos ENSVPAG00000007328 8364 Xenopus tropicalis ENSXETG00000020292
9601 Pongo abelii 100448249 9646 Ailuropoda melanoleuca 100467794
9103 Meleagris gallopavo 100542490 28377 Anolis carolinensis 100564659
61853 Nomascus leucogenys 100580616 400682 Amphimedon queenslandica 100639179
30195 Bombus terrestris 100648431 8128 Oreochromis niloticus 100706145
10141 Cavia porcellus 100717571 132113 Bombus impatiens 100742193
10029 Cricetulus griseus 100754116 7463 Apis florea 100865795
143995 Megachile rotundata 100875661 9597 Pan paniscus 100969842
39432 Saimiri boliviensis 101050360 31033 Takifugu rubripes 101064562
9595 Gorilla gorilla 101137217 9669 Mustela putorius furo 101687381
43179 Ictidomys tridecemlineatus 101974404 10090 Mus musculus 17129
7227 Drosophila melanogaster 33529 7460 Apis mellifera 412601
7955 Danio rerio 445564 7668 Strongylocentrotus purpuratus 582943
7070 Tribolium castaneum 659927 9544 Macaca mulatta 712645
10020 Dipodomys ordii ENSDORG00000004533 9365 Erinaceus europaeus ENSEEUG00000001684
9371 Echinops telfairi ENSETEG00000019912 9606 Homo sapiens ENSG00000113658
69293 Gasterosteus aculeatus ENSGACG00000018718 9031 Gallus gallus ENSGALG00000017050
8049 Gadus morhua ENSGMOG00000005788 9315 Macropus eugenii ENSMEUG00000005813
59463 Myotis lucifugus ENSMLUG00000002321 9813 Procavia capensis ENSPCAG00000006817
7757 Petromyzon marinus ENSPMAG00000009833 13735 Pelodiscus sinensis ENSPSIG00000003731
42254 Sorex araneus ENSSARG00000009234 9305 Sarcophilus harrisii ENSSHAG00000006806
9823 Sus scrofa ENSSSCG00000025920 59729 Taeniopygia guttata ENSTGUG00000001214
99883 Tetraodon nigroviridis ENSTNIG00000003701 9478 Tarsius syrichta ENSTSYG00000005318
8083 Xiphophorus maculatus ENSXMAG00000016280

Paralogs
100341544