Basic Information
Gene ID 768050
Gene Name SMAD5
Full Name Uncharacterized protein
Organism Bos taurus [9913]

Cross Reference
UniProt F1MD43 UniGene Bt.28212
PDB NULL OMIM NULL
KEGG bta:768050 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSBTAP00000029021 Gene3D G3DSA:2.60.200.10 IPR017855 263 465 6.50e-97 SMAD domain-like
ENSBTAP00000029021 Gene3D G3DSA:3.90.520.10 IPR013019 5 144 8.60e-62 MAD homology, MH1
ENSBTAP00000029021 PANTHER PTHR13703 IPR013790 1 465 0.00e-00 Dwarfin
ENSBTAP00000029021 Pfam PF03165 IPR003619 32 132 4.80e-42 MAD homology 1, Dwarfin-type
ENSBTAP00000029021 Pfam PF03166 IPR001132 266 442 7.40e-78 SMAD domain, Dwarfin-type
ENSBTAP00000029021 ProSiteProfiles PS51075 IPR013019 13 137 0.00e-00 MAD homology, MH1
ENSBTAP00000029021 ProSiteProfiles PS51076 IPR001132 271 465 0.00e-00 SMAD domain, Dwarfin-type
ENSBTAP00000029021 SMART SM00523 IPR003619 26 135 4.80e-71 MAD homology 1, Dwarfin-type
ENSBTAP00000029021 SMART SM00524 IPR001132 269 441 2.50e-108 SMAD domain, Dwarfin-type
ENSBTAP00000029021 SUPERFAMILY SSF49879 IPR008984 235 456 0.00e-00 SMAD/FHA domain
ENSBTAP00000029021 SUPERFAMILY SSF56366 IPR013019 14 132 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSBTAP00000029021 PF03166 0 MH2 MH2 domain
ENSBTAP00000029021 PF03165 2.29953e-42 MH1 MH1 domain
ENSBTAP00000029021 PF10401 1.1e-06 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
ENSBTAP00000029021 GO:0001657 biological_process ureteric bud development
ENSBTAP00000029021 GO:0002051 biological_process osteoblast fate commitment
ENSBTAP00000029021 GO:0006351 biological_process transcription, DNA-templated
ENSBTAP00000029021 GO:0006468 biological_process protein phosphorylation
ENSBTAP00000029021 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
ENSBTAP00000029021 GO:0030509 biological_process BMP signaling pathway
ENSBTAP00000029021 GO:0045669 biological_process positive regulation of osteoblast differentiation
ENSBTAP00000029021 GO:0051216 biological_process cartilage development
ENSBTAP00000029021 GO:0060348 biological_process bone development
ENSBTAP00000029021 GO:0071773 biological_process cellular response to BMP stimulus
ENSBTAP00000029021 GO:1901522 biological_process positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
ENSBTAP00000029021 GO:0005634 cellular_component nucleus
ENSBTAP00000029021 GO:0005667 cellular_component transcription factor complex
ENSBTAP00000029021 GO:0005737 cellular_component cytoplasm
ENSBTAP00000029021 GO:0000979 molecular_function RNA polymerase II core promoter sequence-specific DNA binding
ENSBTAP00000029021 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSBTAP00000029021 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100011974 9258 Ornithorhynchus anatinus 100089852
7425 Nasonia vitripennis 100116381 7029 Acyrthosiphon pisum 100167170
6087 Hydra magnipapillata 100211577 10224 Saccoglossus kowalevskii 100303484
9986 Oryctolagus cuniculus 100342616 9646 Ailuropoda melanoleuca 100467794
9103 Meleagris gallopavo 100542490 28377 Anolis carolinensis 100564659
61853 Nomascus leucogenys 100580616 400682 Amphimedon queenslandica 100639179
30195 Bombus terrestris 100648431 9785 Loxodonta africana 100676711
8128 Oreochromis niloticus 100706145 10141 Cavia porcellus 100717571
132113 Bombus impatiens 100742193 10029 Cricetulus griseus 100754116
7463 Apis florea 100865795 143995 Megachile rotundata 100875661
34638 Metaseiulus occidentalis 100907251 9597 Pan paniscus 100969842
9555 Papio anubis 101017482 39432 Saimiri boliviensis 101050360
31033 Takifugu rubripes 101064562 9595 Gorilla gorilla 101137217
9669 Mustela putorius furo 101687381 43179 Ictidomys tridecemlineatus 101974404
7897 Latimeria chalumnae 102346718 10090 Mus musculus 17129
6239 Caenorhabditis elegans 176229 7227 Drosophila melanogaster 33529
7955 Danio rerio 445564 9598 Pan troglodytes 450142
7668 Strongylocentrotus purpuratus 582943 7070 Tribolium castaneum 659927
9544 Macaca mulatta 712645 9685 Felis catus 101081602
9615 Canis familiaris 475456 9483 Callithrix jacchus ENSCJAG00000005968
9361 Dasypus novemcinctus ENSDNOG00000006004 132908 Pteropus vampyrus ENSPVAG00000016214
37347 Tupaia belangeri ENSTBEG00000011491 9358 Choloepus hoffmanni ENSCHOG00000009259
10020 Dipodomys ordii ENSDORG00000004533 9796 Equus caballus ENSECAG00000022649
9365 Erinaceus europaeus ENSEEUG00000001684 9371 Echinops telfairi ENSETEG00000019912
9606 Homo sapiens ENSG00000113658 69293 Gasterosteus aculeatus ENSGACG00000018718
9031 Gallus gallus ENSGALG00000017050 8049 Gadus morhua ENSGMOG00000005788
9315 Macropus eugenii ENSMEUG00000005813 30608 Microcebus murinus ENSMICG00000003343
59463 Myotis lucifugus ENSMLUG00000002321 30611 Otolemur garnettii ENSOGAG00000002742
9978 Ochotona princeps ENSOPRG00000010102 8090 Oryzias latipes ENSORLG00000007377
9813 Procavia capensis ENSPCAG00000006817 7757 Petromyzon marinus ENSPMAG00000009833
13735 Pelodiscus sinensis ENSPSIG00000003731 10116 Rattus norvegicus ENSRNOG00000018483
42254 Sorex araneus ENSSARG00000009234 9305 Sarcophilus harrisii ENSSHAG00000006806
9823 Sus scrofa ENSSSCG00000025920 59729 Taeniopygia guttata ENSTGUG00000001214
99883 Tetraodon nigroviridis ENSTNIG00000003701 9478 Tarsius syrichta ENSTSYG00000005318
9739 Tursiops truncatus ENSTTRG00000016274 30538 Vicugna pacos ENSVPAG00000007328
8083 Xiphophorus maculatus ENSXMAG00000016280

Paralogs
540806