Basic Information | |||
Gene ID | 41709 | ||
Gene Name | foxo; Afx; CG3143 | ||
Full Name | Forkhead box protein O | ||
Organism | Drosophila melanogaster [7227] |
Cross Reference | |||
UniProt | Q95V55 | UniGene | Dm.3957 |
PDB | NULL | OMIM | NULL |
KEGG | dme:Dmel_CG3143 | UCSC | CG3143-RB |
Protein Interactions | |
DIP | NULL |
IntAct | Q95V55 |
MINT | MINT-831229 |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
FBpp0089344 | Gene3D | G3DSA:1.10.10.10 | IPR011991 | 87 | 176 | 1.90e-44 | Winged helix-turn-helix DNA-binding domain |
FBpp0089344 | Pfam | PF00250 | IPR001766 | 98 | 180 | 5.00e-22 | Transcription factor, fork head |
FBpp0089344 | PRINTS | PR00053 | IPR001766 | 116 | 133 | 7.20e-12 | Transcription factor, fork head |
FBpp0089344 | PRINTS | PR00053 | IPR001766 | 144 | 161 | 7.20e-12 | Transcription factor, fork head |
FBpp0089344 | PRINTS | PR00053 | IPR001766 | 95 | 108 | 7.20e-12 | Transcription factor, fork head |
FBpp0089344 | ProSitePatterns | PS00658 | IPR018122 | 144 | 150 | - | Transcription factor, fork head, conserved site |
FBpp0089344 | ProSiteProfiles | PS50039 | IPR001766 | 95 | 201 | 0.00e-00 | Transcription factor, fork head |
FBpp0089344 | SMART | SM00339 | IPR001766 | 93 | 182 | 3.20e-44 | Transcription factor, fork head |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
FBpp0089344 | PF00250 | 5e-22 | Fork_head | Fork head domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
FBpp0089344 | GO:0006351 | biological_process | transcription, DNA-templated |
FBpp0089344 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
FBpp0089344 | GO:0007049 | biological_process | cell cycle |
FBpp0089344 | GO:0007275 | biological_process | multicellular organismal development |
FBpp0089344 | GO:0008285 | biological_process | negative regulation of cell proliferation |
FBpp0089344 | GO:0010259 | biological_process | multicellular organismal aging |
FBpp0089344 | GO:0019216 | biological_process | regulation of lipid metabolic process |
FBpp0089344 | GO:0030154 | biological_process | cell differentiation |
FBpp0089344 | GO:0030308 | biological_process | negative regulation of cell growth |
FBpp0089344 | GO:0040008 | biological_process | regulation of growth |
FBpp0089344 | GO:0042593 | biological_process | glucose homeostasis |
FBpp0089344 | GO:0046627 | biological_process | negative regulation of insulin receptor signaling pathway |
FBpp0089344 | GO:0005634 | cellular_component | nucleus |
FBpp0089344 | GO:0005737 | cellular_component | cytoplasm |
FBpp0089344 | GO:0003677 | molecular_function | DNA binding |
FBpp0089344 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
FBpp0089344 | GO:0043565 | molecular_function | sequence-specific DNA binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
7029 | Acyrthosiphon pisum | 100168097 | 10224 | Saccoglossus kowalevskii | 100303473 |
132113 | Bombus impatiens | 100745007 | 10029 | Cricetulus griseus | 100756577 |
143995 | Megachile rotundata | 100882630 | 39432 | Saimiri boliviensis | 101039948 |
31033 | Takifugu rubripes | 101072519 | 9595 | Gorilla gorilla | 101151399 |
9669 | Mustela putorius furo | 101684130 | 8083 | Xiphophorus maculatus | 102225439 |
9606 | Homo sapiens | 2309 | 7425 | Nasonia vitripennis | 100123890 |
6087 | Hydra magnipapillata | 100202184 | 8090 | Oryzias latipes | 100301620 |
9601 | Pongo abelii | 100460676 | 400682 | Amphimedon queenslandica | 100635906 |
30195 | Bombus terrestris | 100643217 | 7463 | Apis florea | 100867766 |
34638 | Metaseiulus occidentalis | 100899828 | 30611 | Otolemur garnettii | 100948347 |
9597 | Pan paniscus | 100996020 | 9555 | Papio anubis | 101017109 |
9598 | Pan troglodytes | 467352 | 10090 | Mus musculus | 56484 |
7668 | Strongylocentrotus purpuratus | 585334 | 10116 | Rattus norvegicus | 84482 |
28377 | Anolis carolinensis | ENSACAG00000016628 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000011714 |
9913 | Bos taurus | ENSBTAG00000044105 | 7719 | Ciona intestinalis | ENSCING00000023214 |
9483 | Callithrix jacchus | ENSCJAG00000017816 | 51511 | Ciona savignyi | ENSCSAVG00000008339 |
10020 | Dipodomys ordii | ENSDORG00000013871 | 9796 | Equus caballus | ENSECAG00000015262 |
9365 | Erinaceus europaeus | ENSEEUG00000014132 | 9685 | Felis catus | ENSFCAG00000024925 |
69293 | Gasterosteus aculeatus | ENSGACG00000017029 | 9031 | Gallus gallus | ENSGALG00000017034 |
8049 | Gadus morhua | ENSGMOG00000005771 | 7897 | Latimeria chalumnae | ENSLACG00000009595 |
9785 | Loxodonta africana | ENSLAFG00000028324 | 9103 | Meleagris gallopavo | ENSMGAG00000002173 |
13616 | Monodelphis domestica | ENSMODG00000017333 | 61853 | Nomascus leucogenys | ENSNLEG00000001131 |
9986 | Oryctolagus cuniculus | ENSOCUG00000010471 | 8128 | Oreochromis niloticus | ENSONIG00000016186 |
9813 | Procavia capensis | ENSPCAG00000005483 | 13735 | Pelodiscus sinensis | ENSPSIG00000007776 |
9305 | Sarcophilus harrisii | ENSSHAG00000003662 | 9823 | Sus scrofa | ENSSSCG00000009370 |
43179 | Ictidomys tridecemlineatus | ENSSTOG00000009697 | 37347 | Tupaia belangeri | ENSTBEG00000011894 |
59729 | Taeniopygia guttata | ENSTGUG00000012008 | 9478 | Tarsius syrichta | ENSTSYG00000006122 |
30538 | Vicugna pacos | ENSVPAG00000000815 | 9615 | Canis familiaris | 481954 |
7955 | Danio rerio | 567969 | 7070 | Tribolium castaneum | 664090 |
7460 | Apis mellifera | 727091 | 10141 | Cavia porcellus | ENSCPOG00000021906 |
9361 | Dasypus novemcinctus | ENSDNOG00000005257 | 9371 | Echinops telfairi | ENSETEG00000004130 |
9315 | Macropus eugenii | ENSMEUG00000012979 | 30608 | Microcebus murinus | ENSMICG00000014311 |
59463 | Myotis lucifugus | ENSMLUG00000029037 | 9544 | Macaca mulatta | ENSMMUG00000032429 |
9258 | Ornithorhynchus anatinus | ENSOANG00000015514 | 9978 | Ochotona princeps | ENSOPRG00000008735 |
132908 | Pteropus vampyrus | ENSPVAG00000012042 | 42254 | Sorex araneus | ENSSARG00000008583 |
99883 | Tetraodon nigroviridis | ENSTNIG00000011758 | 9739 | Tursiops truncatus | ENSTTRG00000017232 |
8364 | Xenopus tropicalis | ENSXETG00000012944 |