Basic Information
Gene ID 481954
Gene Name FOXO3
Full Name Uncharacterized protein
Organism Canis familiaris [9615]

Cross Reference
UniProt F1PD83 UniGene NULL
PDB NULL OMIM NULL
KEGG cfa:481954 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSCAFP00000005627 Gene3D G3DSA:1.10.10.10 IPR011991 148 236 6.60e-43 Winged helix-turn-helix DNA-binding domain
ENSCAFP00000005627 Pfam PF00250 IPR001766 158 239 4.70e-21 Transcription factor, fork head
ENSCAFP00000005627 PRINTS PR00053 IPR001766 155 168 3.10e-11 Transcription factor, fork head
ENSCAFP00000005627 PRINTS PR00053 IPR001766 176 193 3.10e-11 Transcription factor, fork head
ENSCAFP00000005627 PRINTS PR00053 IPR001766 204 221 3.10e-11 Transcription factor, fork head
ENSCAFP00000005627 ProSitePatterns PS00658 IPR018122 204 210 - Transcription factor, fork head, conserved site
ENSCAFP00000005627 ProSiteProfiles PS50039 IPR001766 155 249 0.00e-00 Transcription factor, fork head
ENSCAFP00000005627 SMART SM00339 IPR001766 153 243 4.30e-48 Transcription factor, fork head

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSCAFP00000005627 PF00250 2.5e-21 Fork_head Fork head domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSCAFP00000005627 GO:0006351 biological_process transcription, DNA-templated
ENSCAFP00000005627 GO:0006915 biological_process apoptotic process
ENSCAFP00000005627 GO:0006974 biological_process cellular response to DNA damage stimulus
ENSCAFP00000005627 GO:0008286 biological_process insulin receptor signaling pathway
ENSCAFP00000005627 GO:0043066 biological_process negative regulation of apoptotic process
ENSCAFP00000005627 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSCAFP00000005627 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSCAFP00000005627 GO:0005634 cellular_component nucleus
ENSCAFP00000005627 GO:0005737 cellular_component cytoplasm
ENSCAFP00000005627 GO:0005829 cellular_component cytosol
ENSCAFP00000005627 GO:0003677 molecular_function DNA binding
ENSCAFP00000005627 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSCAFP00000005627 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100770315 7897 Latimeria chalumnae 102359675
7425 Nasonia vitripennis 100123890 7029 Acyrthosiphon pisum 100168097
6087 Hydra magnipapillata 100202184 8090 Oryzias latipes 100301621
10224 Saccoglossus kowalevskii 100303473 400682 Amphimedon queenslandica 100635906
30195 Bombus terrestris 100643217 8128 Oreochromis niloticus 100700657
132113 Bombus impatiens 100745007 7463 Apis florea 100867766
34638 Metaseiulus occidentalis 100899828 30611 Otolemur garnettii 100948347
9597 Pan paniscus 100976373 9555 Papio anubis 101022550
39432 Saimiri boliviensis 101039948 31033 Takifugu rubripes 101072269
9669 Mustela putorius furo 101684130 43179 Ictidomys tridecemlineatus 101957921
8083 Xiphophorus maculatus 102217263 59463 Myotis lucifugus 102440021
9606 Homo sapiens 2309 10116 Rattus norvegicus 294515
7227 Drosophila melanogaster 41709 9598 Pan troglodytes 462921
10090 Mus musculus 56484 7668 Strongylocentrotus purpuratus 585334
7070 Tribolium castaneum 664090 7460 Apis mellifera 727091
9646 Ailuropoda melanoleuca ENSAMEG00000008158 7719 Ciona intestinalis ENSCING00000023214
51511 Ciona savignyi ENSCSAVG00000008339 7955 Danio rerio ENSDARG00000042904
10020 Dipodomys ordii ENSDORG00000013871 9365 Erinaceus europaeus ENSEEUG00000014132
9371 Echinops telfairi ENSETEG00000004130 9685 Felis catus ENSFCAG00000030227
69293 Gasterosteus aculeatus ENSGACG00000008910 9031 Gallus gallus ENSGALG00000015297
9595 Gorilla gorilla ENSGGOG00000003517 8049 Gadus morhua ENSGMOG00000012748
9315 Macropus eugenii ENSMEUG00000014523 13616 Monodelphis domestica ENSMODG00000017333
9258 Ornithorhynchus anatinus ENSOANG00000000768 9986 Oryctolagus cuniculus ENSOCUG00000010471
9813 Procavia capensis ENSPCAG00000008041 13735 Pelodiscus sinensis ENSPSIG00000007776
132908 Pteropus vampyrus ENSPVAG00000001137 42254 Sorex araneus ENSSARG00000005586
9305 Sarcophilus harrisii ENSSHAG00000018299 9823 Sus scrofa ENSSSCG00000004387
37347 Tupaia belangeri ENSTBEG00000012196 59729 Taeniopygia guttata ENSTGUG00000012135
99883 Tetraodon nigroviridis ENSTNIG00000019314 9739 Tursiops truncatus ENSTTRG00000017232
30538 Vicugna pacos ENSVPAG00000000815 8364 Xenopus tropicalis ENSXETG00000012944
10141 Cavia porcellus ENSCPOG00000021906 9361 Dasypus novemcinctus ENSDNOG00000005257
30608 Microcebus murinus ENSMICG00000014311