Basic Information | |||
Gene ID | 450142 | ||
Gene Name | SMAD1 | ||
Full Name | SMAD family member 1 | ||
Organism | Pan troglodytes [9598] |
Cross Reference | |||
UniProt | H2QQ88 | UniGene | Ptr.4464 |
PDB | NULL | OMIM | NULL |
KEGG | ptr:450142 | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSPTRP00000028297 | Gene3D | G3DSA:2.60.200.10 | IPR017855 | 263 | 465 | 1.30e-97 | SMAD domain-like |
ENSPTRP00000028297 | Gene3D | G3DSA:3.90.520.10 | IPR013019 | 5 | 144 | 2.30e-61 | MAD homology, MH1 |
ENSPTRP00000028297 | PANTHER | PTHR13703 | IPR013790 | 1 | 465 | 0.00e-00 | Dwarfin |
ENSPTRP00000028297 | Pfam | PF03165 | IPR003619 | 31 | 131 | 4.60e-42 | MAD homology 1, Dwarfin-type |
ENSPTRP00000028297 | Pfam | PF03166 | IPR001132 | 266 | 442 | 3.10e-78 | SMAD domain, Dwarfin-type |
ENSPTRP00000028297 | ProSiteProfiles | PS51075 | IPR013019 | 12 | 136 | 0.00e-00 | MAD homology, MH1 |
ENSPTRP00000028297 | ProSiteProfiles | PS51076 | IPR001132 | 271 | 465 | 0.00e-00 | SMAD domain, Dwarfin-type |
ENSPTRP00000028297 | SMART | SM00523 | IPR003619 | 25 | 134 | 1.50e-70 | MAD homology 1, Dwarfin-type |
ENSPTRP00000028297 | SMART | SM00524 | IPR001132 | 269 | 441 | 5.70e-110 | SMAD domain, Dwarfin-type |
ENSPTRP00000028297 | SUPERFAMILY | SSF49879 | IPR008984 | 221 | 456 | 0.00e-00 | SMAD/FHA domain |
ENSPTRP00000028297 | SUPERFAMILY | SSF56366 | IPR013019 | 13 | 131 | 0.00e-00 | MAD homology, MH1 |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSPTRP00000028297 | PF03166 | 0 | MH2 | MH2 domain |
ENSPTRP00000028297 | PF03165 | 1.69978e-42 | MH1 | MH1 domain |
ENSPTRP00000028297 | PF10401 | 7.2e-07 | IRF-3 | Interferon-regulatory factor 3 |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSPTRP00000028297 | GO:0001657 | biological_process | ureteric bud development |
ENSPTRP00000028297 | GO:0002051 | biological_process | osteoblast fate commitment |
ENSPTRP00000028297 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSPTRP00000028297 | GO:0006468 | biological_process | protein phosphorylation |
ENSPTRP00000028297 | GO:0007179 | biological_process | transforming growth factor beta receptor signaling pathway |
ENSPTRP00000028297 | GO:0030509 | biological_process | BMP signaling pathway |
ENSPTRP00000028297 | GO:0045669 | biological_process | positive regulation of osteoblast differentiation |
ENSPTRP00000028297 | GO:0051216 | biological_process | cartilage development |
ENSPTRP00000028297 | GO:0060348 | biological_process | bone development |
ENSPTRP00000028297 | GO:0071773 | biological_process | cellular response to BMP stimulus |
ENSPTRP00000028297 | GO:1901522 | biological_process | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus |
ENSPTRP00000028297 | GO:0005634 | cellular_component | nucleus |
ENSPTRP00000028297 | GO:0005667 | cellular_component | transcription factor complex |
ENSPTRP00000028297 | GO:0005737 | cellular_component | cytoplasm |
ENSPTRP00000028297 | GO:0000979 | molecular_function | RNA polymerase II core promoter sequence-specific DNA binding |
ENSPTRP00000028297 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSPTRP00000028297 | GO:0046872 | molecular_function | metal ion binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
400682 | Amphimedon queenslandica | 100639179 | 59463 | Myotis lucifugus | 102433398 |
10090 | Mus musculus | 17129 | 13616 | Monodelphis domestica | 100011974 |
9258 | Ornithorhynchus anatinus | 100089852 | 7425 | Nasonia vitripennis | 100116381 |
7029 | Acyrthosiphon pisum | 100167170 | 6087 | Hydra magnipapillata | 100211577 |
59729 | Taeniopygia guttata | 100219645 | 10224 | Saccoglossus kowalevskii | 100303484 |
9986 | Oryctolagus cuniculus | 100341544 | 28377 | Anolis carolinensis | 100556712 |
61853 | Nomascus leucogenys | 100580616 | 30195 | Bombus terrestris | 100648431 |
10141 | Cavia porcellus | 100717571 | 132113 | Bombus impatiens | 100742193 |
10029 | Cricetulus griseus | 100768619 | 7463 | Apis florea | 100865795 |
143995 | Megachile rotundata | 100875661 | 34638 | Metaseiulus occidentalis | 100907251 |
9597 | Pan paniscus | 100992068 | 9555 | Papio anubis | 101017482 |
39432 | Saimiri boliviensis | 101036852 | 9685 | Felis catus | 101085713 |
9595 | Gorilla gorilla | 101137217 | 9669 | Mustela putorius furo | 101678475 |
8083 | Xiphophorus maculatus | 102217583 | 7897 | Latimeria chalumnae | 102346718 |
6239 | Caenorhabditis elegans | 176229 | 7227 | Drosophila melanogaster | 33529 |
9615 | Canis familiaris | 475456 | 9544 | Macaca mulatta | 574340 |
7668 | Strongylocentrotus purpuratus | 582943 | 7070 | Tribolium castaneum | 659927 |
9913 | Bos taurus | 768050 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000016645 |
9358 | Choloepus hoffmanni | ENSCHOG00000009259 | 9483 | Callithrix jacchus | ENSCJAG00000005968 |
9361 | Dasypus novemcinctus | ENSDNOG00000006004 | 9796 | Equus caballus | ENSECAG00000022649 |
9365 | Erinaceus europaeus | ENSEEUG00000008384 | 9606 | Homo sapiens | ENSG00000113658 |
8049 | Gadus morhua | ENSGMOG00000007465 | 9315 | Macropus eugenii | ENSMEUG00000005813 |
9103 | Meleagris gallopavo | ENSMGAG00000003725 | 8128 | Oreochromis niloticus | ENSONIG00000010000 |
9978 | Ochotona princeps | ENSOPRG00000012775 | 8090 | Oryzias latipes | ENSORLG00000007377 |
9813 | Procavia capensis | ENSPCAG00000009132 | 7757 | Petromyzon marinus | ENSPMAG00000009833 |
13735 | Pelodiscus sinensis | ENSPSIG00000016396 | 132908 | Pteropus vampyrus | ENSPVAG00000014298 |
10116 | Rattus norvegicus | ENSRNOG00000018483 | 42254 | Sorex araneus | ENSSARG00000009234 |
9305 | Sarcophilus harrisii | ENSSHAG00000006387 | 9823 | Sus scrofa | ENSSSCG00000025920 |
43179 | Ictidomys tridecemlineatus | ENSSTOG00000010836 | 99883 | Tetraodon nigroviridis | ENSTNIG00000017720 |
31033 | Takifugu rubripes | ENSTRUG00000014344 | 9478 | Tarsius syrichta | ENSTSYG00000000913 |
9739 | Tursiops truncatus | ENSTTRG00000008086 | 30538 | Vicugna pacos | ENSVPAG00000007328 |
9371 | Echinops telfairi | ENSETEG00000016533 | 69293 | Gasterosteus aculeatus | ENSGACG00000017230 |
Paralogs | |||
452539 |