Basic Information
Gene ID 462921
Gene Name FOXO3
Full Name Forkhead box O3
Organism Pan troglodytes [9598]

Cross Reference
UniProt H2R710 UniGene NULL
PDB NULL OMIM NULL
KEGG ptr:462921 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPTRP00000049754 Gene3D G3DSA:1.10.10.10 IPR011991 150 238 6.60e-43 Winged helix-turn-helix DNA-binding domain
ENSPTRP00000049754 Pfam PF00250 IPR001766 160 241 4.70e-21 Transcription factor, fork head
ENSPTRP00000049754 PRINTS PR00053 IPR001766 157 170 3.20e-11 Transcription factor, fork head
ENSPTRP00000049754 PRINTS PR00053 IPR001766 178 195 3.20e-11 Transcription factor, fork head
ENSPTRP00000049754 PRINTS PR00053 IPR001766 206 223 3.20e-11 Transcription factor, fork head
ENSPTRP00000049754 ProSitePatterns PS00658 IPR018122 206 212 - Transcription factor, fork head, conserved site
ENSPTRP00000049754 ProSiteProfiles PS50039 IPR001766 157 251 0.00e-00 Transcription factor, fork head
ENSPTRP00000049754 SMART SM00339 IPR001766 155 245 4.30e-48 Transcription factor, fork head

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPTRP00000049754 PF00250 2.7e-21 Fork_head Fork head domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPTRP00000049754 GO:0006351 biological_process transcription, DNA-templated
ENSPTRP00000049754 GO:0006915 biological_process apoptotic process
ENSPTRP00000049754 GO:0006974 biological_process cellular response to DNA damage stimulus
ENSPTRP00000049754 GO:0008286 biological_process insulin receptor signaling pathway
ENSPTRP00000049754 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSPTRP00000049754 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSPTRP00000049754 GO:0005634 cellular_component nucleus
ENSPTRP00000049754 GO:0005737 cellular_component cytoplasm
ENSPTRP00000049754 GO:0005829 cellular_component cytosol
ENSPTRP00000049754 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPTRP00000049754 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100118797 6087 Hydra magnipapillata 100202184
10224 Saccoglossus kowalevskii 100303473 400682 Amphimedon queenslandica 100635906
132113 Bombus impatiens 100745007 10029 Cricetulus griseus 100770315
143995 Megachile rotundata 100882630 34638 Metaseiulus occidentalis 100899828
30611 Otolemur garnettii 100948347 9597 Pan paniscus 100976373
39432 Saimiri boliviensis 101039948 9669 Mustela putorius furo 101684130
43179 Ictidomys tridecemlineatus 101957921 8083 Xiphophorus maculatus 102217263
7897 Latimeria chalumnae 102359675 59463 Myotis lucifugus 102440021
9606 Homo sapiens 2309 10116 Rattus norvegicus 294515
8090 Oryzias latipes 100301621 30195 Bombus terrestris 100643217
8128 Oreochromis niloticus 100700657 7463 Apis florea 100867766
9555 Papio anubis 101022550 31033 Takifugu rubripes 101072269
10090 Mus musculus 56484 9646 Ailuropoda melanoleuca ENSAMEG00000008158
51511 Ciona savignyi ENSCSAVG00000008339 69293 Gasterosteus aculeatus ENSGACG00000008910
9031 Gallus gallus ENSGALG00000015297 9595 Gorilla gorilla ENSGGOG00000003517
9813 Procavia capensis ENSPCAG00000008041 13735 Pelodiscus sinensis ENSPSIG00000007776
9305 Sarcophilus harrisii ENSSHAG00000018299 9615 Canis familiaris 481954
7070 Tribolium castaneum 664090 7460 Apis mellifera 727091
7719 Ciona intestinalis ENSCING00000023214 10141 Cavia porcellus ENSCPOG00000021906
7955 Danio rerio ENSDARG00000042904 9361 Dasypus novemcinctus ENSDNOG00000005257
10020 Dipodomys ordii ENSDORG00000013871 9365 Erinaceus europaeus ENSEEUG00000014132
9371 Echinops telfairi ENSETEG00000004130 9685 Felis catus ENSFCAG00000030227
8049 Gadus morhua ENSGMOG00000012748 9315 Macropus eugenii ENSMEUG00000014523
30608 Microcebus murinus ENSMICG00000014311 13616 Monodelphis domestica ENSMODG00000017333
9258 Ornithorhynchus anatinus ENSOANG00000000768 9986 Oryctolagus cuniculus ENSOCUG00000010471
132908 Pteropus vampyrus ENSPVAG00000001137 42254 Sorex araneus ENSSARG00000005586
9823 Sus scrofa ENSSSCG00000004387 37347 Tupaia belangeri ENSTBEG00000012196
59729 Taeniopygia guttata ENSTGUG00000012135 99883 Tetraodon nigroviridis ENSTNIG00000019314
9739 Tursiops truncatus ENSTTRG00000017232 30538 Vicugna pacos ENSVPAG00000000815
8364 Xenopus tropicalis ENSXETG00000012944