Basic Information
Gene ID 5314 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name PKHD1; FCYT, TIGM1
Full Name Fibrocystin
Organism Homo sapiens [9606]

Cross Reference
UniProt P08F94 UniGene Hs.662050
PDB NULL OMIM 606702
KEGG hsa:5314 UCSC uc003pai.3

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000360158 Gene3D G3DSA:2.160.20.10 IPR012334 2230 2342 4.00e-06 Pectin lyase fold
ENSP00000360158 Gene3D G3DSA:2.160.20.10 IPR012334 2403 2510 4.00e-06 Pectin lyase fold
ENSP00000360158 Gene3D G3DSA:2.160.20.10 IPR012334 3004 3214 4.10e-09 Pectin lyase fold
ENSP00000360158 Gene3D G3DSA:2.60.40.10 IPR013783 1018 1102 6.90e-08 Immunoglobulin-like fold
ENSP00000360158 Gene3D G3DSA:2.60.40.10 IPR013783 1185 1296 1.80e-10 Immunoglobulin-like fold
ENSP00000360158 Gene3D G3DSA:2.60.40.10 IPR013783 1383 1470 4.40e-08 Immunoglobulin-like fold
ENSP00000360158 Gene3D G3DSA:2.60.40.10 IPR013783 1495 1559 1.70e-06 Immunoglobulin-like fold
ENSP00000360158 Gene3D G3DSA:2.60.40.10 IPR013783 1560 1645 1.40e-10 Immunoglobulin-like fold
ENSP00000360158 Gene3D G3DSA:2.60.40.10 IPR013783 249 313 1.20e-12 Immunoglobulin-like fold
ENSP00000360158 Gene3D G3DSA:2.60.40.10 IPR013783 911 998 1.90e-06 Immunoglobulin-like fold
ENSP00000360158 PANTHER PTHR11915:SF30 IPR028839 467 3188 0.00e-00 Fibrocystin
ENSP00000360158 Pfam PF01833 IPR002909 1019 1102 2.00e-06 IPT domain
ENSP00000360158 Pfam PF01833 IPR002909 1200 1260 1.20e-04 IPT domain
ENSP00000360158 Pfam PF01833 IPR002909 1389 1470 4.20e-07 IPT domain
ENSP00000360158 Pfam PF01833 IPR002909 1486 1556 1.20e-06 IPT domain
ENSP00000360158 Pfam PF01833 IPR002909 1577 1642 3.20e-07 IPT domain
ENSP00000360158 Pfam PF01833 IPR002909 261 313 4.60e-09 IPT domain
ENSP00000360158 Pfam PF01833 IPR002909 945 1000 2.00e-08 IPT domain
ENSP00000360158 Pfam PF10162 IPR019316 1932 2052 6.70e-30 G8 domain
ENSP00000360158 Pfam PF10162 IPR019316 2749 2872 8.90e-20 G8 domain
ENSP00000360158 ProSiteProfiles PS51484 IPR019316 1932 2053 0.00e-00 G8 domain
ENSP00000360158 ProSiteProfiles PS51484 IPR019316 2747 2873 0.00e-00 G8 domain
ENSP00000360158 SMART SM00429 IPR002909 1018 1103 4.70e-03 IPT domain
ENSP00000360158 SMART SM00429 IPR002909 1107 1193 6.20e-02 IPT domain
ENSP00000360158 SMART SM00429 IPR002909 1195 1294 1.20e-04 IPT domain
ENSP00000360158 SMART SM00429 IPR002909 1388 1482 2.20e-03 IPT domain
ENSP00000360158 SMART SM00429 IPR002909 1572 1659 2.00e-02 IPT domain
ENSP00000360158 SMART SM00429 IPR002909 258 355 1.00e-06 IPT domain
ENSP00000360158 SMART SM00710 IPR006626 1077 1099 6.60e+00 Parallel beta-helix repeat
ENSP00000360158 SMART SM00710 IPR006626 2226 2248 2.60e+01 Parallel beta-helix repeat
ENSP00000360158 SMART SM00710 IPR006626 2249 2271 7.00e+00 Parallel beta-helix repeat
ENSP00000360158 SMART SM00710 IPR006626 2292 2325 3.60e+00 Parallel beta-helix repeat
ENSP00000360158 SMART SM00710 IPR006626 2326 2347 2.50e+00 Parallel beta-helix repeat
ENSP00000360158 SMART SM00710 IPR006626 2409 2431 2.20e+00 Parallel beta-helix repeat
ENSP00000360158 SMART SM00710 IPR006626 2469 2502 1.80e+01 Parallel beta-helix repeat
ENSP00000360158 SMART SM00710 IPR006626 3010 3032 5.40e+00 Parallel beta-helix repeat
ENSP00000360158 SMART SM00710 IPR006626 3033 3055 2.10e-02 Parallel beta-helix repeat
ENSP00000360158 SMART SM00710 IPR006626 3086 3108 2.10e+00 Parallel beta-helix repeat
ENSP00000360158 SUPERFAMILY SSF51126 IPR011050 2192 2445 0.00e-00 Pectin lyase fold/virulence factor
ENSP00000360158 SUPERFAMILY SSF51126 IPR011050 2991 2997 0.00e-00 Pectin lyase fold/virulence factor
ENSP00000360158 SUPERFAMILY SSF51126 IPR011050 3025 3183 0.00e-00 Pectin lyase fold/virulence factor
ENSP00000360158 SUPERFAMILY SSF81296 IPR014756 1017 1104 0.00e-00 Immunoglobulin E-set
ENSP00000360158 SUPERFAMILY SSF81296 IPR014756 1198 1254 0.00e-00 Immunoglobulin E-set
ENSP00000360158 SUPERFAMILY SSF81296 IPR014756 1388 1473 0.00e-00 Immunoglobulin E-set
ENSP00000360158 SUPERFAMILY SSF81296 IPR014756 1571 1645 0.00e-00 Immunoglobulin E-set
ENSP00000360158 SUPERFAMILY SSF81296 IPR014756 260 313 0.00e-00 Immunoglobulin E-set
ENSP00000360158 SUPERFAMILY SSF81296 IPR014756 930 1001 0.00e-00 Immunoglobulin E-set

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000360158 PF01833 0 TIG IPT/TIG domain
ENSP00000360158 PF10162 0 G8 G8 domain
ENSP00000360158 PF13229 4.2e-25 Beta_helix Right handed beta helix region
ENSP00000360158 PF05048 5.1e-05 NosD Periplasmic copper-binding protein (NosD)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000360158 GO:0016021 cellular_component integral component of membrane
ENSP00000360158 GO:0004872 molecular_function receptor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100766925 39432 Saimiri boliviensis 101033860
9796 Equus caballus 100069045 61853 Nomascus leucogenys 100589423
9597 Pan paniscus 100981760 9598 Pan troglodytes 462760
9615 Canis familiaris 474934 9913 Bos taurus ENSBTAG00000011237
9358 Choloepus hoffmanni ENSCHOG00000004476 9483 Callithrix jacchus ENSCJAG00000011434
10141 Cavia porcellus ENSCPOG00000010473 9361 Dasypus novemcinctus ENSDNOG00000014976
9365 Erinaceus europaeus ENSEEUG00000007593 9371 Echinops telfairi ENSETEG00000000841
9685 Felis catus ENSFCAG00000009219 9031 Gallus gallus ENSGALG00000016679
9595 Gorilla gorilla ENSGGOG00000010943 7897 Latimeria chalumnae ENSLACG00000014664
9103 Meleagris gallopavo ENSMGAG00000014240 30608 Microcebus murinus ENSMICG00000008392
59463 Myotis lucifugus ENSMLUG00000014592 13616 Monodelphis domestica ENSMODG00000018828
9669 Mustela putorius furo ENSMPUG00000009027 9258 Ornithorhynchus anatinus ENSOANG00000003131
9978 Ochotona princeps ENSOPRG00000009388 9601 Pongo abelii ENSPPYG00000016702
132908 Pteropus vampyrus ENSPVAG00000016307 42254 Sorex araneus ENSSARG00000005954
9823 Sus scrofa ENSSSCG00000001746 43179 Ictidomys tridecemlineatus ENSSTOG00000013374
59729 Taeniopygia guttata ENSTGUG00000013268 9478 Tarsius syrichta ENSTSYG00000003882
8364 Xenopus tropicalis ENSXETG00000021681 9646 Ailuropoda melanoleuca ENSAMEG00000008599
10020 Dipodomys ordii ENSDORG00000002272 9315 Macropus eugenii ENSMEUG00000008419
9544 Macaca mulatta ENSMMUG00000016993 9986 Oryctolagus cuniculus ENSOCUG00000004246
30611 Otolemur garnettii ENSOGAG00000015530 9813 Procavia capensis ENSPCAG00000016682
37347 Tupaia belangeri ENSTBEG00000000191 9739 Tursiops truncatus ENSTTRG00000008368
30538 Vicugna pacos ENSVPAG00000000543