Basic Information
Gene ID 5914 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name RARA; NR1B1
Full Name Retinoic acid receptor alpha
Organism Homo sapiens [9606]

Cross Reference
UniProt P10276 UniGene Hs.654583
PDB 4DQM OMIM 612376
KEGG hsa:5914 UCSC uc010wfe.2

Protein Interactions
DIP DIP-34N
IntAct P10276
MINT MINT-123081
STRING 9606.ENSP00000254066

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000377648 Gene3D G3DSA:1.10.565.10 IPR008946 176 432 2.10e-94 Nuclear hormone receptor, ligand-binding
ENSP00000377648 Gene3D G3DSA:3.30.50.10 IPR013088 102 175 1.20e-33 Zinc finger, NHR/GATA-type
ENSP00000377648 Pfam PF00104 IPR000536 236 410 2.20e-30 Nuclear hormone receptor, ligand-binding, core
ENSP00000377648 Pfam PF00105 IPR001628 103 171 1.30e-32 Zinc finger, nuclear hormone receptor-type
ENSP00000377648 PRINTS PR00047 IPR001628 104 120 6.30e-19 Zinc finger, nuclear hormone receptor-type
ENSP00000377648 PRINTS PR00047 IPR001628 120 135 6.30e-19 Zinc finger, nuclear hormone receptor-type
ENSP00000377648 PRINTS PR00047 IPR001628 153 161 6.30e-19 Zinc finger, nuclear hormone receptor-type
ENSP00000377648 PRINTS PR00047 IPR001628 161 169 6.30e-19 Zinc finger, nuclear hormone receptor-type
ENSP00000377648 PRINTS PR00398 IPR001723 165 175 2.80e-34 Steroid hormone receptor
ENSP00000377648 PRINTS PR00398 IPR001723 247 268 2.80e-34 Steroid hormone receptor
ENSP00000377648 PRINTS PR00398 IPR001723 268 284 2.80e-34 Steroid hormone receptor
ENSP00000377648 PRINTS PR00398 IPR001723 335 350 2.80e-34 Steroid hormone receptor
ENSP00000377648 PRINTS PR00398 IPR001723 392 409 2.80e-34 Steroid hormone receptor
ENSP00000377648 PRINTS PR01292 IPR003078 170 183 2.20e-103 Retinoic acid receptor
ENSP00000377648 PRINTS PR01292 IPR003078 192 216 2.20e-103 Retinoic acid receptor
ENSP00000377648 PRINTS PR01292 IPR003078 217 233 2.20e-103 Retinoic acid receptor
ENSP00000377648 PRINTS PR01292 IPR003078 239 256 2.20e-103 Retinoic acid receptor
ENSP00000377648 PRINTS PR01292 IPR003078 290 314 2.20e-103 Retinoic acid receptor
ENSP00000377648 PRINTS PR01292 IPR003078 327 339 2.20e-103 Retinoic acid receptor
ENSP00000377648 PRINTS PR01292 IPR003078 357 378 2.20e-103 Retinoic acid receptor
ENSP00000377648 PRINTS PR01292 IPR003078 401 416 2.20e-103 Retinoic acid receptor
ENSP00000377648 PRINTS PR01292 IPR003078 424 437 2.20e-103 Retinoic acid receptor
ENSP00000377648 PRINTS PR01292 IPR003078 76 93 2.20e-103 Retinoic acid receptor
ENSP00000377648 ProSitePatterns PS00031 IPR001628 104 130 - Zinc finger, nuclear hormone receptor-type
ENSP00000377648 ProSiteProfiles PS51030 IPR001628 101 176 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSP00000377648 SMART SM00399 IPR001628 101 172 1.40e-42 Zinc finger, nuclear hormone receptor-type
ENSP00000377648 SMART SM00430 IPR000536 246 404 8.20e-37 Nuclear hormone receptor, ligand-binding, core
ENSP00000377648 SUPERFAMILY SSF48508 IPR008946 153 431 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000377648 PF00105 1.3e-32 zf-C4 Zinc finger, C4 type (two domains)
ENSP00000377648 PF00104 1.4e-30 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000377648 GO:0005634 cellular_component nucleus
ENSP00000377648 GO:0003707 molecular_function steroid hormone receptor activity
ENSP00000377648 GO:0003708 molecular_function retinoic acid receptor activity
ENSP00000377648 GO:0008270 molecular_function zinc ion binding
ENSP00000377648 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
39432 Saimiri boliviensis 101036514 43179 Ictidomys tridecemlineatus 101974461
30195 Bombus terrestris 100644185 9597 Pan paniscus 100967548
9555 Papio anubis 101019389 10116 Rattus norvegicus 24705
10020 Dipodomys ordii ENSDORG00000015185 13616 Monodelphis domestica ENSMODG00000013112
61853 Nomascus leucogenys ENSNLEG00000001793 30611 Otolemur garnettii ENSOGAG00000024257
9598 Pan troglodytes ENSPTRG00000009120 99883 Tetraodon nigroviridis ENSTNIG00000012850
8364 Xenopus tropicalis ENSXETG00000024390 8083 Xiphophorus maculatus ENSXMAG00000014632
9371 Echinops telfairi ENSETEG00000013732 31033 Takifugu rubripes ENSTRUG00000016415
9739 Tursiops truncatus ENSTTRG00000016901

Paralogs
5915 5916