Basic Information
Gene ID 5916 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name RARG; NR1B3
Full Name Retinoic acid receptor gamma
Organism Homo sapiens [9606]

Cross Reference
UniProt P13631 UniGene Hs.733399
PDB 4LBD OMIM 180190
KEGG hsa:5916 UCSC uc010sob.2

Protein Interactions
DIP NULL
IntAct P13631
MINT MINT-3007936
STRING 9606.ENSP00000332695

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000377947 Gene3D G3DSA:1.10.565.10 IPR008946 162 419 3.80e-90 Nuclear hormone receptor, ligand-binding
ENSP00000377947 Gene3D G3DSA:3.30.50.10 IPR013088 87 161 8.20e-34 Zinc finger, NHR/GATA-type
ENSP00000377947 Pfam PF00104 IPR000536 227 395 4.90e-30 Nuclear hormone receptor, ligand-binding, core
ENSP00000377947 Pfam PF00105 IPR001628 89 157 7.80e-33 Zinc finger, nuclear hormone receptor-type
ENSP00000377947 PRINTS PR00047 IPR001628 106 121 1.40e-19 Zinc finger, nuclear hormone receptor-type
ENSP00000377947 PRINTS PR00047 IPR001628 139 147 1.40e-19 Zinc finger, nuclear hormone receptor-type
ENSP00000377947 PRINTS PR00047 IPR001628 147 155 1.40e-19 Zinc finger, nuclear hormone receptor-type
ENSP00000377947 PRINTS PR00047 IPR001628 90 106 1.40e-19 Zinc finger, nuclear hormone receptor-type
ENSP00000377947 PRINTS PR00398 IPR001723 151 161 9.10e-35 Steroid hormone receptor
ENSP00000377947 PRINTS PR00398 IPR001723 233 254 9.10e-35 Steroid hormone receptor
ENSP00000377947 PRINTS PR00398 IPR001723 254 270 9.10e-35 Steroid hormone receptor
ENSP00000377947 PRINTS PR00398 IPR001723 321 336 9.10e-35 Steroid hormone receptor
ENSP00000377947 PRINTS PR00398 IPR001723 378 395 9.10e-35 Steroid hormone receptor
ENSP00000377947 PRINTS PR01292 IPR003078 156 169 5.80e-103 Retinoic acid receptor
ENSP00000377947 PRINTS PR01292 IPR003078 178 202 5.80e-103 Retinoic acid receptor
ENSP00000377947 PRINTS PR01292 IPR003078 203 219 5.80e-103 Retinoic acid receptor
ENSP00000377947 PRINTS PR01292 IPR003078 225 242 5.80e-103 Retinoic acid receptor
ENSP00000377947 PRINTS PR01292 IPR003078 276 300 5.80e-103 Retinoic acid receptor
ENSP00000377947 PRINTS PR01292 IPR003078 313 325 5.80e-103 Retinoic acid receptor
ENSP00000377947 PRINTS PR01292 IPR003078 343 364 5.80e-103 Retinoic acid receptor
ENSP00000377947 PRINTS PR01292 IPR003078 387 402 5.80e-103 Retinoic acid receptor
ENSP00000377947 PRINTS PR01292 IPR003078 410 423 5.80e-103 Retinoic acid receptor
ENSP00000377947 PRINTS PR01292 IPR003078 62 79 5.80e-103 Retinoic acid receptor
ENSP00000377947 ProSitePatterns PS00031 IPR001628 90 116 - Zinc finger, nuclear hormone receptor-type
ENSP00000377947 ProSiteProfiles PS51030 IPR001628 87 162 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSP00000377947 SMART SM00399 IPR001628 87 158 5.20e-43 Zinc finger, nuclear hormone receptor-type
ENSP00000377947 SMART SM00430 IPR000536 232 390 2.90e-36 Nuclear hormone receptor, ligand-binding, core
ENSP00000377947 SUPERFAMILY SSF48508 IPR008946 139 417 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000377947 PF00105 7.8e-33 zf-C4 Zinc finger, C4 type (two domains)
ENSP00000377947 PF00104 2.6e-30 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000377947 GO:0005634 cellular_component nucleus
ENSP00000377947 GO:0003677 molecular_function DNA binding
ENSP00000377947 GO:0003707 molecular_function steroid hormone receptor activity
ENSP00000377947 GO:0003708 molecular_function retinoic acid receptor activity
ENSP00000377947 GO:0008270 molecular_function zinc ion binding
ENSP00000377947 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100062026 8090 Oryzias latipes 100125535
8128 Oreochromis niloticus 100707970 10029 Cricetulus griseus 100769591
9305 Sarcophilus harrisii 100920749 9555 Papio anubis 101014448
39432 Saimiri boliviensis 101028779 31033 Takifugu rubripes 101073854
9685 Felis catus 101083275 9669 Mustela putorius furo 101684419
43179 Ictidomys tridecemlineatus 101976820 8083 Xiphophorus maculatus 102236110
10090 Mus musculus 19411 9597 Pan paniscus 100988215
28377 Anolis carolinensis ENSACAG00000006832 9315 Macropus eugenii ENSMEUG00000005385
61853 Nomascus leucogenys ENSNLEG00000017714 9601 Pongo abelii ENSPPYG00000004572
9478 Tarsius syrichta ENSTSYG00000012005 10116 Rattus norvegicus 685072
9646 Ailuropoda melanoleuca ENSAMEG00000012299 10141 Cavia porcellus ENSCPOG00000014819
7955 Danio rerio ENSDARG00000054003 10020 Dipodomys ordii ENSDORG00000016232
9371 Echinops telfairi ENSETEG00000001526 69293 Gasterosteus aculeatus ENSGACG00000009372
9595 Gorilla gorilla ENSGGOG00000003215 9785 Loxodonta africana ENSLAFG00000008347
59463 Myotis lucifugus ENSMLUG00000017284 9986 Oryctolagus cuniculus ENSOCUG00000001432
30611 Otolemur garnettii ENSOGAG00000026655 9978 Ochotona princeps ENSOPRG00000005114
9813 Procavia capensis ENSPCAG00000012059 132908 Pteropus vampyrus ENSPVAG00000009374
37347 Tupaia belangeri ENSTBEG00000015684 99883 Tetraodon nigroviridis ENSTNIG00000015051
9739 Tursiops truncatus ENSTTRG00000002778

Paralogs
5914 5915