Basic Information
Gene ID ENSAMEG00000014048
Gene Name STAT1
Full Name Signal transducer and activator of transcription
Organism Ailuropoda melanoleuca [9646]

Cross Reference
UniProt G1M6K0 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSAMEP00000014970 Gene3D G3DSA:1.10.238.10 IPR011992 120 240 5.10e-49 EF-hand domain pair
ENSAMEP00000014970 Gene3D G3DSA:1.10.238.10 IPR011992 880 1000 2.60e-50 EF-hand domain pair
ENSAMEP00000014970 Gene3D G3DSA:1.10.532.10 IPR013799 466 586 4.80e-47 STAT transcription factor, protein interaction
ENSAMEP00000014970 Gene3D G3DSA:1.20.1050.20 IPR013800 602 780 1.60e-65 STAT transcription factor, all-alpha
ENSAMEP00000014970 Gene3D G3DSA:2.60.40.630 IPR012345 29 119 1.70e-23 STAT transcription factor, DNA-binding, subdomain
ENSAMEP00000014970 Gene3D G3DSA:2.60.40.630 IPR012345 781 868 2.50e-23 STAT transcription factor, DNA-binding, subdomain
ENSAMEP00000014970 Gene3D G3DSA:3.30.505.10 IPR000980 1001 1130 3.90e-52 SH2 domain
ENSAMEP00000014970 Gene3D G3DSA:3.30.505.10 IPR000980 241 348 9.50e-47 SH2 domain
ENSAMEP00000014970 PANTHER PTHR11801 IPR001217 467 1165 0.00e-00 Transcription factor STAT
ENSAMEP00000014970 Pfam PF00017 IPR000980 236 290 4.50e-11 SH2 domain
ENSAMEP00000014970 Pfam PF00017 IPR000980 998 1057 2.30e-08 SH2 domain
ENSAMEP00000014970 Pfam PF01017 IPR013800 602 780 2.20e-63 STAT transcription factor, all-alpha
ENSAMEP00000014970 Pfam PF02864 IPR013801 29 226 3.60e-73 STAT transcription factor, DNA-binding
ENSAMEP00000014970 Pfam PF02864 IPR013801 868 986 1.60e-55 STAT transcription factor, DNA-binding
ENSAMEP00000014970 Pfam PF02865 IPR013799 467 586 1.70e-43 STAT transcription factor, protein interaction
ENSAMEP00000014970 Pfam PF12162 IPR022752 1134 1158 7.00e-12 Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal
ENSAMEP00000014970 ProSiteProfiles PS50001 IPR000980 232 310 0.00e-00 SH2 domain
ENSAMEP00000014970 ProSiteProfiles PS50001 IPR000980 992 1089 0.00e-00 SH2 domain
ENSAMEP00000014970 SMART SM00252 IPR000980 990 1106 1.90e-03 SH2 domain
ENSAMEP00000014970 SMART SM00964 IPR013799 467 587 1.30e-67 STAT transcription factor, protein interaction
ENSAMEP00000014970 SUPERFAMILY SSF47655 IPR015988 599 780 0.00e-00 STAT transcription factor, coiled coil
ENSAMEP00000014970 SUPERFAMILY SSF48092 IPR013799 466 586 0.00e-00 STAT transcription factor, protein interaction
ENSAMEP00000014970 SUPERFAMILY SSF49417 IPR008967 29 227 0.00e-00 p53-like transcription factor, DNA-binding
ENSAMEP00000014970 SUPERFAMILY SSF49417 IPR008967 780 987 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSAMEP00000014970 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSAMEP00000014970 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSAMEP00000014970 PF02865 1.69557e-43 STAT_int STAT protein, protein interaction domain
ENSAMEP00000014970 PF00017 4e-23 SH2 SH2 domain
ENSAMEP00000014970 PF12162 3.2e-12 STAT1_TAZ2bind STAT1 TAZ2 binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSAMEP00000014970 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSAMEP00000014970 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSAMEP00000014970 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSAMEP00000014970 GO:0005634 cellular_component nucleus
ENSAMEP00000014970 GO:0005737 cellular_component cytoplasm
ENSAMEP00000014970 GO:0004871 molecular_function signal transducer activity
ENSAMEP00000014970 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10116 Rattus norvegicus 25124 9913 Bos taurus 510814
8128 Oreochromis niloticus 100696359 10029 Cricetulus griseus 100755609
9597 Pan paniscus 100971620 9555 Papio anubis 101005886
39432 Saimiri boliviensis 101030811 7897 Latimeria chalumnae 102353760
13735 Pelodiscus sinensis 102462741 9544 Macaca mulatta 693650
28377 Anolis carolinensis ENSACAG00000005909 9358 Choloepus hoffmanni ENSCHOG00000013865
9361 Dasypus novemcinctus ENSDNOG00000007325 9365 Erinaceus europaeus ENSEEUG00000002778
9685 Felis catus ENSFCAG00000013725 9031 Gallus gallus ENSGALG00000007651
9595 Gorilla gorilla ENSGGOG00000000611 8049 Gadus morhua ENSGMOG00000012431
9785 Loxodonta africana ENSLAFG00000001475 9103 Meleagris gallopavo ENSMGAG00000006382
30608 Microcebus murinus ENSMICG00000002941 9669 Mustela putorius furo ENSMPUG00000012530
61853 Nomascus leucogenys ENSNLEG00000006694 9986 Oryctolagus cuniculus ENSOCUG00000002455
30611 Otolemur garnettii ENSOGAG00000003038 9978 Ochotona princeps ENSOPRG00000008589
8090 Oryzias latipes ENSORLG00000000162 9813 Procavia capensis ENSPCAG00000006029
9601 Pongo abelii ENSPPYG00000013027 9598 Pan troglodytes ENSPTRG00000012749
42254 Sorex araneus ENSSARG00000013346 59729 Taeniopygia guttata ENSTGUG00000010768
99883 Tetraodon nigroviridis ENSTNIG00000017161 9739 Tursiops truncatus ENSTTRG00000001134
30538 Vicugna pacos ENSVPAG00000011543 8364 Xenopus tropicalis ENSXETG00000004649
8083 Xiphophorus maculatus ENSXMAG00000001594 10141 Cavia porcellus ENSCPOG00000012673
7955 Danio rerio ENSDARG00000006266 10020 Dipodomys ordii ENSDORG00000011139
9796 Equus caballus ENSECAG00000009039 9371 Echinops telfairi ENSETEG00000017040
69293 Gasterosteus aculeatus ENSGACG00000015589 9315 Macropus eugenii ENSMEUG00000012165
59463 Myotis lucifugus ENSMLUG00000010083 13616 Monodelphis domestica ENSMODG00000011747
9258 Ornithorhynchus anatinus ENSOANG00000001310 132908 Pteropus vampyrus ENSPVAG00000004735
9305 Sarcophilus harrisii ENSSHAG00000016913 9823 Sus scrofa ENSSSCG00000016057
43179 Ictidomys tridecemlineatus ENSSTOG00000008620 37347 Tupaia belangeri ENSTBEG00000017412
31033 Takifugu rubripes ENSTRUG00000000102 9478 Tarsius syrichta ENSTSYG00000007651