Basic Information
Gene ID ENSNLEG00000006694
Gene Name NULL
Full Name Signal transducer and activator of transcription
Organism Nomascus leucogenys [61853]

Cross Reference
UniProt G1R4R1 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSNLEP00000008183 Gene3D G3DSA:1.10.238.10 IPR011992 461 581 5.80e-51 EF-hand domain pair
ENSNLEP00000008183 Gene3D G3DSA:1.10.532.10 IPR013799 1 121 2.80e-47 STAT transcription factor, protein interaction
ENSNLEP00000008183 Gene3D G3DSA:1.20.1050.20 IPR013800 137 317 3.30e-68 STAT transcription factor, all-alpha
ENSNLEP00000008183 Gene3D G3DSA:2.60.40.630 IPR012345 318 460 7.40e-66 STAT transcription factor, DNA-binding, subdomain
ENSNLEP00000008183 Gene3D G3DSA:3.30.505.10 IPR000980 582 711 1.60e-52 SH2 domain
ENSNLEP00000008183 PANTHER PTHR11801 IPR001217 2 750 0.00e-00 Transcription factor STAT
ENSNLEP00000008183 Pfam PF00017 IPR000980 578 638 6.30e-09 SH2 domain
ENSNLEP00000008183 Pfam PF01017 IPR013800 137 315 5.00e-64 STAT transcription factor, all-alpha
ENSNLEP00000008183 Pfam PF02864 IPR013801 317 567 4.40e-120 STAT transcription factor, DNA-binding
ENSNLEP00000008183 Pfam PF02865 IPR013799 2 121 1.20e-43 STAT transcription factor, protein interaction
ENSNLEP00000008183 Pfam PF12162 IPR022752 715 739 4.20e-12 Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal
ENSNLEP00000008183 ProSiteProfiles PS50001 IPR000980 573 670 0.00e-00 SH2 domain
ENSNLEP00000008183 SMART SM00252 IPR000980 575 687 9.50e-04 SH2 domain
ENSNLEP00000008183 SMART SM00964 IPR013799 2 122 1.40e-66 STAT transcription factor, protein interaction
ENSNLEP00000008183 SUPERFAMILY SSF47655 IPR015988 134 317 0.00e-00 STAT transcription factor, coiled coil
ENSNLEP00000008183 SUPERFAMILY SSF48092 IPR013799 1 121 0.00e-00 STAT transcription factor, protein interaction
ENSNLEP00000008183 SUPERFAMILY SSF49417 IPR008967 317 568 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSNLEP00000008183 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSNLEP00000008183 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSNLEP00000008183 PF02865 1.20512e-43 STAT_int STAT protein, protein interaction domain
ENSNLEP00000008183 PF12162 1.8e-12 STAT1_TAZ2bind STAT1 TAZ2 binding domain
ENSNLEP00000008183 PF00017 8.1e-10 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSNLEP00000008183 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSNLEP00000008183 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSNLEP00000008183 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSNLEP00000008183 GO:0005634 cellular_component nucleus
ENSNLEP00000008183 GO:0005737 cellular_component cytoplasm
ENSNLEP00000008183 GO:0003677 molecular_function DNA binding
ENSNLEP00000008183 GO:0004871 molecular_function signal transducer activity
ENSNLEP00000008183 GO:0005509 molecular_function calcium ion binding
ENSNLEP00000008183 GO:0019901 molecular_function protein kinase binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9555 Papio anubis 101005886 7897 Latimeria chalumnae 102353760
10090 Mus musculus 20849 10116 Rattus norvegicus 25124
9615 Canis familiaris 490967 9913 Bos taurus 510814
9646 Ailuropoda melanoleuca ENSAMEG00000014048 10141 Cavia porcellus ENSCPOG00000012673
7955 Danio rerio ENSDARG00000006266 10020 Dipodomys ordii ENSDORG00000011139
9796 Equus caballus ENSECAG00000009039 9371 Echinops telfairi ENSETEG00000017040
69293 Gasterosteus aculeatus ENSGACG00000015589 9315 Macropus eugenii ENSMEUG00000012165
30608 Microcebus murinus ENSMICG00000002941 59463 Myotis lucifugus ENSMLUG00000010083
13616 Monodelphis domestica ENSMODG00000011747 9483 Callithrix jacchus 100402355
8128 Oreochromis niloticus 100696359 10029 Cricetulus griseus 100755609
9597 Pan paniscus 100971620 39432 Saimiri boliviensis 101030811
13735 Pelodiscus sinensis 102462741 9606 Homo sapiens 6775
9544 Macaca mulatta 693650 28377 Anolis carolinensis ENSACAG00000005909
9358 Choloepus hoffmanni ENSCHOG00000013865 9361 Dasypus novemcinctus ENSDNOG00000007325
9365 Erinaceus europaeus ENSEEUG00000002197 9685 Felis catus ENSFCAG00000013725
9031 Gallus gallus ENSGALG00000007651 9595 Gorilla gorilla ENSGGOG00000000611
8049 Gadus morhua ENSGMOG00000012431 9785 Loxodonta africana ENSLAFG00000001475
9103 Meleagris gallopavo ENSMGAG00000006382 9669 Mustela putorius furo ENSMPUG00000012530
9258 Ornithorhynchus anatinus ENSOANG00000022638 9986 Oryctolagus cuniculus ENSOCUG00000002455
30611 Otolemur garnettii ENSOGAG00000003038 9978 Ochotona princeps ENSOPRG00000008589
8090 Oryzias latipes ENSORLG00000000162 9813 Procavia capensis ENSPCAG00000005867
9601 Pongo abelii ENSPPYG00000013027 9598 Pan troglodytes ENSPTRG00000012749
42254 Sorex araneus ENSSARG00000014231 59729 Taeniopygia guttata ENSTGUG00000010768
99883 Tetraodon nigroviridis ENSTNIG00000017161 30538 Vicugna pacos ENSVPAG00000011543
8364 Xenopus tropicalis ENSXETG00000004649 8083 Xiphophorus maculatus ENSXMAG00000001594
7757 Petromyzon marinus ENSPMAG00000002770 132908 Pteropus vampyrus ENSPVAG00000004735
9305 Sarcophilus harrisii ENSSHAG00000016913 9823 Sus scrofa ENSSSCG00000016057
43179 Ictidomys tridecemlineatus ENSSTOG00000008620 37347 Tupaia belangeri ENSTBEG00000017412
31033 Takifugu rubripes ENSTRUG00000000102 9478 Tarsius syrichta ENSTSYG00000007651
9739 Tursiops truncatus ENSTTRG00000001134