Basic Information
Gene ID ENSSTOG00000008620
Gene Name STAT1
Full Name Signal transducer and activator of transcription
Organism Ictidomys tridecemlineatus [43179]

Cross Reference
UniProt I3MC04 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSTOP00000007745 Gene3D G3DSA:1.10.238.10 IPR011992 468 588 1.20e-50 EF-hand domain pair
ENSSTOP00000007745 Gene3D G3DSA:1.10.532.10 IPR013799 1 121 2.50e-47 STAT transcription factor, protein interaction
ENSSTOP00000007745 Gene3D G3DSA:1.20.1050.20 IPR013800 137 317 2.70e-68 STAT transcription factor, all-alpha
ENSSTOP00000007745 Gene3D G3DSA:2.60.40.630 IPR012345 318 467 8.30e-63 STAT transcription factor, DNA-binding, subdomain
ENSSTOP00000007745 Gene3D G3DSA:3.30.505.10 IPR000980 589 718 9.50e-53 SH2 domain
ENSSTOP00000007745 PANTHER PTHR11801 IPR001217 2 757 0.00e-00 Transcription factor STAT
ENSSTOP00000007745 Pfam PF00017 IPR000980 585 645 6.40e-09 SH2 domain
ENSSTOP00000007745 Pfam PF01017 IPR013800 137 315 2.00e-65 STAT transcription factor, all-alpha
ENSSTOP00000007745 Pfam PF02864 IPR013801 317 574 5.60e-115 STAT transcription factor, DNA-binding
ENSSTOP00000007745 Pfam PF02865 IPR013799 2 121 9.30e-44 STAT transcription factor, protein interaction
ENSSTOP00000007745 Pfam PF12162 IPR022752 722 746 4.50e-12 Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal
ENSSTOP00000007745 ProSiteProfiles PS50001 IPR000980 580 677 0.00e-00 SH2 domain
ENSSTOP00000007745 SMART SM00252 IPR000980 582 694 6.60e-04 SH2 domain
ENSSTOP00000007745 SMART SM00964 IPR013799 2 122 1.30e-67 STAT transcription factor, protein interaction
ENSSTOP00000007745 SUPERFAMILY SSF47655 IPR015988 134 317 0.00e-00 STAT transcription factor, coiled coil
ENSSTOP00000007745 SUPERFAMILY SSF48092 IPR013799 1 121 0.00e-00 STAT transcription factor, protein interaction
ENSSTOP00000007745 SUPERFAMILY SSF49417 IPR008967 317 575 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSTOP00000007745 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSSTOP00000007745 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSSTOP00000007745 PF02865 9.24857e-44 STAT_int STAT protein, protein interaction domain
ENSSTOP00000007745 PF12162 2e-12 STAT1_TAZ2bind STAT1 TAZ2 binding domain
ENSSTOP00000007745 PF00017 6.8e-10 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSTOP00000007745 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSSTOP00000007745 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSSTOP00000007745 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSSTOP00000007745 GO:0005634 cellular_component nucleus
ENSSTOP00000007745 GO:0005737 cellular_component cytoplasm
ENSSTOP00000007745 GO:0003677 molecular_function DNA binding
ENSSTOP00000007745 GO:0004871 molecular_function signal transducer activity
ENSSTOP00000007745 GO:0005509 molecular_function calcium ion binding
ENSSTOP00000007745 GO:0019901 molecular_function protein kinase binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10090 Mus musculus 20849 10116 Rattus norvegicus 25124
9913 Bos taurus 510814 10141 Cavia porcellus ENSCPOG00000012673
7955 Danio rerio ENSDARG00000006266 10020 Dipodomys ordii ENSDORG00000011139
69293 Gasterosteus aculeatus ENSGACG00000015589 9315 Macropus eugenii ENSMEUG00000012165
59463 Myotis lucifugus ENSMLUG00000010083 7757 Petromyzon marinus ENSPMAG00000002770
132908 Pteropus vampyrus ENSPVAG00000004735 9305 Sarcophilus harrisii ENSSHAG00000016913
9483 Callithrix jacchus 100402355 8128 Oreochromis niloticus 100696359
10029 Cricetulus griseus 100755609 9597 Pan paniscus 100971620
9555 Papio anubis 101005886 39432 Saimiri boliviensis 101030811
7897 Latimeria chalumnae 102353760 13735 Pelodiscus sinensis 102462741
9606 Homo sapiens 6775 9544 Macaca mulatta 693650
28377 Anolis carolinensis ENSACAG00000005909 9646 Ailuropoda melanoleuca ENSAMEG00000014048
9358 Choloepus hoffmanni ENSCHOG00000013865 9361 Dasypus novemcinctus ENSDNOG00000007325
9796 Equus caballus ENSECAG00000009039 9365 Erinaceus europaeus ENSEEUG00000002197
9371 Echinops telfairi ENSETEG00000017040 9685 Felis catus ENSFCAG00000013725
9031 Gallus gallus ENSGALG00000007651 9595 Gorilla gorilla ENSGGOG00000000611
8049 Gadus morhua ENSGMOG00000012431 9785 Loxodonta africana ENSLAFG00000001475
9103 Meleagris gallopavo ENSMGAG00000006382 30608 Microcebus murinus ENSMICG00000002941
13616 Monodelphis domestica ENSMODG00000011747 9669 Mustela putorius furo ENSMPUG00000012530
61853 Nomascus leucogenys ENSNLEG00000006694 9258 Ornithorhynchus anatinus ENSOANG00000022638
9986 Oryctolagus cuniculus ENSOCUG00000002455 30611 Otolemur garnettii ENSOGAG00000003038
9978 Ochotona princeps ENSOPRG00000008589 8090 Oryzias latipes ENSORLG00000000162
9813 Procavia capensis ENSPCAG00000005867 9601 Pongo abelii ENSPPYG00000013027
9598 Pan troglodytes ENSPTRG00000012749 9823 Sus scrofa ENSSSCG00000016057
59729 Taeniopygia guttata ENSTGUG00000010768 99883 Tetraodon nigroviridis ENSTNIG00000017161
9739 Tursiops truncatus ENSTTRG00000001134 30538 Vicugna pacos ENSVPAG00000011543
8364 Xenopus tropicalis ENSXETG00000004649 8083 Xiphophorus maculatus ENSXMAG00000001594
37347 Tupaia belangeri ENSTBEG00000017412 31033 Takifugu rubripes ENSTRUG00000000102
9478 Tarsius syrichta ENSTSYG00000007651