Basic Information
Gene ID ENSBTAG00000020701
Gene Name MEF2C
Full Name Myocyte-specific enhancer factor 2C
Organism Bos taurus [9913]

Cross Reference
UniProt G3MW05 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSBTAP00000034894 Pfam PF00319 IPR002100 10 59 2.80e-22 Transcription factor, MADS-box
ENSBTAP00000034894 Pfam PF12347 IPR022102 95 155 5.70e-13 Holliday junction regulator protein family C-terminal
ENSBTAP00000034894 PRINTS PR00404 IPR002100 23 38 6.30e-26 Transcription factor, MADS-box
ENSBTAP00000034894 PRINTS PR00404 IPR002100 3 23 6.30e-26 Transcription factor, MADS-box
ENSBTAP00000034894 PRINTS PR00404 IPR002100 38 59 6.30e-26 Transcription factor, MADS-box
ENSBTAP00000034894 ProSitePatterns PS00350 IPR002100 3 57 - Transcription factor, MADS-box
ENSBTAP00000034894 ProSiteProfiles PS50066 IPR002100 1 61 0.00e-00 Transcription factor, MADS-box
ENSBTAP00000034894 SMART SM00432 IPR002100 1 60 8.50e-40 Transcription factor, MADS-box
ENSBTAP00000034894 SUPERFAMILY SSF55455 IPR002100 2 89 0.00e-00 Transcription factor, MADS-box

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSBTAP00000034894 PF00319 1.6e-22 SRF-TF SRF-type transcription factor (DNA-binding and dimerisation domain)
ENSBTAP00000034894 PF12347 2.5e-13 HJURP_C Holliday junction regulator protein family C-terminal repeat

Gene Ontology Annotation
Protein Entry Name Space Description
ENSBTAP00000034894 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSBTAP00000034894 GO:0000165 biological_process MAPK cascade
ENSBTAP00000034894 GO:0006351 biological_process transcription, DNA-templated
ENSBTAP00000034894 GO:0006366 biological_process transcription from RNA polymerase II promoter
ENSBTAP00000034894 GO:0006915 biological_process apoptotic process
ENSBTAP00000034894 GO:0007507 biological_process heart development
ENSBTAP00000034894 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSBTAP00000034894 GO:0071277 biological_process cellular response to calcium ion
ENSBTAP00000034894 GO:0005634 cellular_component nucleus
ENSBTAP00000034894 GO:0005737 cellular_component cytoplasm
ENSBTAP00000034894 GO:0000977 molecular_function RNA polymerase II regulatory region sequence-specific DNA binding
ENSBTAP00000034894 GO:0000981 molecular_function sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSBTAP00000034894 GO:0001077 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
ENSBTAP00000034894 GO:0003677 molecular_function DNA binding
ENSBTAP00000034894 GO:0003682 molecular_function chromatin binding
ENSBTAP00000034894 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSBTAP00000034894 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100122265 6087 Hydra magnipapillata 100204453
10224 Saccoglossus kowalevskii 100313657 9646 Ailuropoda melanoleuca 100464632
400682 Amphimedon queenslandica 100636842 30195 Bombus terrestris 100649884
10141 Cavia porcellus 100725079 132113 Bombus impatiens 100745731
7463 Apis florea 100871942 143995 Megachile rotundata 100877544
9597 Pan paniscus 100975251 9555 Papio anubis 101019513
39432 Saimiri boliviensis 101029713 31033 Takifugu rubripes 101069405
9595 Gorilla gorilla 101139415 9669 Mustela putorius furo 101686957
7897 Latimeria chalumnae 102361694 6239 Caenorhabditis elegans 172732
7227 Drosophila melanogaster 36032 7460 Apis mellifera 413946
9606 Homo sapiens 4205 9598 Pan troglodytes 461760
9615 Canis familiaris 479155 7668 Strongylocentrotus purpuratus 591326
7070 Tribolium castaneum 660448 28377 Anolis carolinensis ENSACAG00000000488
7029 Acyrthosiphon pisum 100572713 10029 Cricetulus griseus 100754401
34638 Metaseiulus occidentalis 100902919 10090 Mus musculus 17261
10020 Dipodomys ordii ENSDORG00000010183 9685 Felis catus ENSFCAG00000011595
30608 Microcebus murinus ENSMICG00000008255 59463 Myotis lucifugus ENSMLUG00000008230
9478 Tarsius syrichta ENSTSYG00000003647 9358 Choloepus hoffmanni ENSCHOG00000010767
7719 Ciona intestinalis ENSCING00000000628 9483 Callithrix jacchus ENSCJAG00000005848
51511 Ciona savignyi ENSCSAVG00000003571 7955 Danio rerio ENSDARG00000057527
9361 Dasypus novemcinctus ENSDNOG00000018848 9796 Equus caballus ENSECAG00000024716
9365 Erinaceus europaeus ENSEEUG00000002968 9371 Echinops telfairi ENSETEG00000015637
69293 Gasterosteus aculeatus ENSGACG00000010270 9031 Gallus gallus ENSGALG00000014645
8049 Gadus morhua ENSGMOG00000000565 9785 Loxodonta africana ENSLAFG00000013761
9315 Macropus eugenii ENSMEUG00000012604 9103 Meleagris gallopavo ENSMGAG00000009283
9544 Macaca mulatta ENSMMUG00000019836 13616 Monodelphis domestica ENSMODG00000020223
61853 Nomascus leucogenys ENSNLEG00000012609 9258 Ornithorhynchus anatinus ENSOANG00000011076
9986 Oryctolagus cuniculus ENSOCUG00000012173 30611 Otolemur garnettii ENSOGAG00000028682
8128 Oreochromis niloticus ENSONIG00000015941 9978 Ochotona princeps ENSOPRG00000012052
8090 Oryzias latipes ENSORLG00000010062 9813 Procavia capensis ENSPCAG00000012944
9601 Pongo abelii ENSPPYG00000015621 13735 Pelodiscus sinensis ENSPSIG00000012244
132908 Pteropus vampyrus ENSPVAG00000009412 10116 Rattus norvegicus ENSRNOG00000033134
42254 Sorex araneus ENSSARG00000012570 9305 Sarcophilus harrisii ENSSHAG00000010347
9823 Sus scrofa ENSSSCG00000014149 43179 Ictidomys tridecemlineatus ENSSTOG00000028856
37347 Tupaia belangeri ENSTBEG00000006794 59729 Taeniopygia guttata ENSTGUG00000000676
99883 Tetraodon nigroviridis ENSTNIG00000015441 9739 Tursiops truncatus ENSTTRG00000003944
30538 Vicugna pacos ENSVPAG00000009789 8364 Xenopus tropicalis ENSXETG00000018788
8083 Xiphophorus maculatus ENSXMAG00000019414