Basic Information
Gene ID ENSFCAG00000002153
Gene Name STAT5A
Full Name Signal transducer and activator of transcription
Organism Felis catus [9685]

Cross Reference
UniProt M3VY00 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSFCAP00000001990 Gene3D G3DSA:1.10.238.10 IPR011992 464 589 2.00e-46 EF-hand domain pair
ENSFCAP00000001990 Gene3D G3DSA:1.10.532.10 IPR013799 1 125 1.20e-48 STAT transcription factor, protein interaction
ENSFCAP00000001990 Gene3D G3DSA:1.20.1050.20 IPR013800 139 195 2.10e-10 STAT transcription factor, all-alpha
ENSFCAP00000001990 Gene3D G3DSA:2.60.40.630 IPR012345 325 463 1.50e-68 STAT transcription factor, DNA-binding, subdomain
ENSFCAP00000001990 Gene3D G3DSA:3.30.505.10 IPR000980 590 699 8.50e-40 SH2 domain
ENSFCAP00000001990 PANTHER PTHR11801 IPR001217 2 766 0.00e-00 Transcription factor STAT
ENSFCAP00000001990 Pfam PF00017 IPR000980 587 660 1.20e-10 SH2 domain
ENSFCAP00000001990 Pfam PF01017 IPR013800 138 183 3.30e-07 STAT transcription factor, all-alpha
ENSFCAP00000001990 Pfam PF02864 IPR013801 324 575 2.40e-99 STAT transcription factor, DNA-binding
ENSFCAP00000001990 Pfam PF02865 IPR013799 2 125 3.20e-48 STAT transcription factor, protein interaction
ENSFCAP00000001990 ProSiteProfiles PS50001 IPR000980 581 678 0.00e-00 SH2 domain
ENSFCAP00000001990 SMART SM00252 IPR000980 579 692 2.00e-08 SH2 domain
ENSFCAP00000001990 SMART SM00964 IPR013799 2 126 2.40e-65 STAT transcription factor, protein interaction
ENSFCAP00000001990 SUPERFAMILY SSF47655 IPR015988 136 200 0.00e-00 STAT transcription factor, coiled coil
ENSFCAP00000001990 SUPERFAMILY SSF48092 IPR013799 1 124 0.00e-00 STAT transcription factor, protein interaction
ENSFCAP00000001990 SUPERFAMILY SSF49417 IPR008967 318 576 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSFCAP00000001990 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSFCAP00000001990 PF02865 0 STAT_int STAT protein, protein interaction domain
ENSFCAP00000001990 PF00017 7.4e-12 SH2 SH2 domain
ENSFCAP00000001990 PF01017 1.5e-07 STAT_alpha STAT protein, all-alpha domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSFCAP00000001990 GO:0001553 biological_process luteinization
ENSFCAP00000001990 GO:0001779 biological_process natural killer cell differentiation
ENSFCAP00000001990 GO:0006351 biological_process transcription, DNA-templated
ENSFCAP00000001990 GO:0007259 biological_process JAK-STAT cascade
ENSFCAP00000001990 GO:0007565 biological_process female pregnancy
ENSFCAP00000001990 GO:0007595 biological_process lactation
ENSFCAP00000001990 GO:0019218 biological_process regulation of steroid metabolic process
ENSFCAP00000001990 GO:0019915 biological_process lipid storage
ENSFCAP00000001990 GO:0030155 biological_process regulation of cell adhesion
ENSFCAP00000001990 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSFCAP00000001990 GO:0038161 biological_process prolactin signaling pathway
ENSFCAP00000001990 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSFCAP00000001990 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSFCAP00000001990 GO:0043029 biological_process T cell homeostasis
ENSFCAP00000001990 GO:0043066 biological_process negative regulation of apoptotic process
ENSFCAP00000001990 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSFCAP00000001990 GO:0045579 biological_process positive regulation of B cell differentiation
ENSFCAP00000001990 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSFCAP00000001990 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSFCAP00000001990 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSFCAP00000001990 GO:0046543 biological_process development of secondary female sexual characteristics
ENSFCAP00000001990 GO:0050729 biological_process positive regulation of inflammatory response
ENSFCAP00000001990 GO:0005634 cellular_component nucleus
ENSFCAP00000001990 GO:0005737 cellular_component cytoplasm
ENSFCAP00000001990 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSFCAP00000001990 GO:0004871 molecular_function signal transducer activity
ENSFCAP00000001990 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100012174 10020 Dipodomys ordii ENSDORG00000000303
7425 Nasonia vitripennis 100121885 7029 Acyrthosiphon pisum 100161101
6087 Hydra magnipapillata 100206878 30195 Bombus terrestris 100647789
132113 Bombus impatiens 100743540 10029 Cricetulus griseus 100755571
7463 Apis florea 100864112 143995 Megachile rotundata 100880948
34638 Metaseiulus occidentalis 100907258 30611 Otolemur garnettii 100958999
9597 Pan paniscus 100988550 9555 Papio anubis 100998364
9669 Mustela putorius furo 101691575 59463 Myotis lucifugus 102423996
7460 Apis mellifera 413742 9598 Pan troglodytes 454681
9544 Macaca mulatta 574129 7070 Tribolium castaneum 657965
7719 Ciona intestinalis 778770 9913 Bos taurus ENSBTAG00000009496
9483 Callithrix jacchus ENSCJAG00000000426 51511 Ciona savignyi ENSCSAVG00000011110
7955 Danio rerio ENSDARG00000019392 9365 Erinaceus europaeus ENSEEUG00000003642
69293 Gasterosteus aculeatus ENSGACG00000008634 8049 Gadus morhua ENSGMOG00000014154
9785 Loxodonta africana ENSLAFG00000014055 9315 Macropus eugenii ENSMEUG00000006640
8128 Oreochromis niloticus ENSONIG00000007261 9813 Procavia capensis ENSPCAG00000010107
10116 Rattus norvegicus ENSRNOG00000019496 43179 Ictidomys tridecemlineatus ENSSTOG00000006713
99883 Tetraodon nigroviridis ENSTNIG00000011707 31033 Takifugu rubripes ENSTRUG00000015454
9739 Tursiops truncatus ENSTTRG00000007155 8364 Xenopus tropicalis ENSXETG00000000836
8083 Xiphophorus maculatus ENSXMAG00000005165 7897 Latimeria chalumnae ENSLACG00000002646
7757 Petromyzon marinus ENSPMAG00000009008 132908 Pteropus vampyrus ENSPVAG00000003881

Paralogs
ENSFCAG00000028112