Basic Information
Gene ID ENSONIG00000007261
Gene Name LOC100690945
Full Name Signal transducer and activator of transcription
Organism Oreochromis niloticus [8128]

Cross Reference
UniProt I3JJW2 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSONIP00000009156 Gene3D G3DSA:1.10.238.10 IPR011992 474 599 1.30e-45 EF-hand domain pair
ENSONIP00000009156 Gene3D G3DSA:1.10.532.10 IPR013799 1 125 3.40e-45 STAT transcription factor, protein interaction
ENSONIP00000009156 Gene3D G3DSA:1.20.1050.20 IPR013800 141 333 1.20e-58 STAT transcription factor, all-alpha
ENSONIP00000009156 Gene3D G3DSA:2.60.40.630 IPR012345 334 473 9.80e-64 STAT transcription factor, DNA-binding, subdomain
ENSONIP00000009156 Gene3D G3DSA:3.30.505.10 IPR000980 600 712 3.00e-43 SH2 domain
ENSONIP00000009156 PANTHER PTHR11801 IPR001217 2 780 0.00e-00 Transcription factor STAT
ENSONIP00000009156 Pfam PF00017 IPR000980 597 676 2.50e-10 SH2 domain
ENSONIP00000009156 Pfam PF01017 IPR013800 140 331 1.50e-54 STAT transcription factor, all-alpha
ENSONIP00000009156 Pfam PF02864 IPR013801 333 585 9.80e-91 STAT transcription factor, DNA-binding
ENSONIP00000009156 Pfam PF02865 IPR013799 2 125 2.30e-45 STAT transcription factor, protein interaction
ENSONIP00000009156 ProSiteProfiles PS50001 IPR000980 591 692 0.00e-00 SH2 domain
ENSONIP00000009156 SMART SM00252 IPR000980 589 682 1.00e-09 SH2 domain
ENSONIP00000009156 SMART SM00964 IPR013799 2 126 4.00e-63 STAT transcription factor, protein interaction
ENSONIP00000009156 SUPERFAMILY SSF47655 IPR015988 139 333 0.00e-00 STAT transcription factor, coiled coil
ENSONIP00000009156 SUPERFAMILY SSF48092 IPR013799 1 125 0.00e-00 STAT transcription factor, protein interaction
ENSONIP00000009156 SUPERFAMILY SSF49417 IPR008967 328 586 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSONIP00000009156 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSONIP00000009156 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSONIP00000009156 PF02865 2.8026e-45 STAT_int STAT protein, protein interaction domain
ENSONIP00000009156 PF00017 2.5e-11 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSONIP00000009156 GO:0001553 biological_process luteinization
ENSONIP00000009156 GO:0001779 biological_process natural killer cell differentiation
ENSONIP00000009156 GO:0006351 biological_process transcription, DNA-templated
ENSONIP00000009156 GO:0007259 biological_process JAK-STAT cascade
ENSONIP00000009156 GO:0007565 biological_process female pregnancy
ENSONIP00000009156 GO:0007595 biological_process lactation
ENSONIP00000009156 GO:0019218 biological_process regulation of steroid metabolic process
ENSONIP00000009156 GO:0019915 biological_process lipid storage
ENSONIP00000009156 GO:0030155 biological_process regulation of cell adhesion
ENSONIP00000009156 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSONIP00000009156 GO:0038161 biological_process prolactin signaling pathway
ENSONIP00000009156 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSONIP00000009156 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSONIP00000009156 GO:0043029 biological_process T cell homeostasis
ENSONIP00000009156 GO:0043066 biological_process negative regulation of apoptotic process
ENSONIP00000009156 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSONIP00000009156 GO:0045579 biological_process positive regulation of B cell differentiation
ENSONIP00000009156 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSONIP00000009156 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSONIP00000009156 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSONIP00000009156 GO:0046543 biological_process development of secondary female sexual characteristics
ENSONIP00000009156 GO:0050729 biological_process positive regulation of inflammatory response
ENSONIP00000009156 GO:0005634 cellular_component nucleus
ENSONIP00000009156 GO:0005737 cellular_component cytoplasm
ENSONIP00000009156 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSONIP00000009156 GO:0004871 molecular_function signal transducer activity
ENSONIP00000009156 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100012174 7029 Acyrthosiphon pisum 100161101
9601 Pongo abelii 100462537 39432 Saimiri boliviensis 101043203
9598 Pan troglodytes 454681 9544 Macaca mulatta 574129
9615 Canis familiaris ENSCAFG00000015509 9361 Dasypus novemcinctus ENSDNOG00000007398
10020 Dipodomys ordii ENSDORG00000000303 9685 Felis catus ENSFCAG00000002153
7897 Latimeria chalumnae ENSLACG00000002646 9103 Meleagris gallopavo ENSMGAG00000003430
9258 Ornithorhynchus anatinus ENSOANG00000006496 7425 Nasonia vitripennis 100121885
6087 Hydra magnipapillata 100206878 9986 Oryctolagus cuniculus 100348267
400682 Amphimedon queenslandica 100641588 30195 Bombus terrestris 100647789
132113 Bombus impatiens 100743540 10029 Cricetulus griseus 100755571
7463 Apis florea 100864112 143995 Megachile rotundata 100880948
34638 Metaseiulus occidentalis 100907258 30611 Otolemur garnettii 100958999
9597 Pan paniscus 100989105 9555 Papio anubis 101000002
9669 Mustela putorius furo 101691575 10090 Mus musculus 20851
10116 Rattus norvegicus 25126 9031 Gallus gallus 395556
9823 Sus scrofa 397340 7460 Apis mellifera 413742
7227 Drosophila melanogaster 42428 7668 Strongylocentrotus purpuratus 576433
7070 Tribolium castaneum 657965 7719 Ciona intestinalis 778770
9646 Ailuropoda melanoleuca ENSAMEG00000006061 9913 Bos taurus ENSBTAG00000009496
9358 Choloepus hoffmanni ENSCHOG00000005387 9483 Callithrix jacchus ENSCJAG00000000426
10141 Cavia porcellus ENSCPOG00000026466 51511 Ciona savignyi ENSCSAVG00000011110
7955 Danio rerio ENSDARG00000019392 9796 Equus caballus ENSECAG00000007847
9365 Erinaceus europaeus ENSEEUG00000003642 9371 Echinops telfairi ENSETEG00000008535
69293 Gasterosteus aculeatus ENSGACG00000015405 9595 Gorilla gorilla ENSGGOG00000008216
8049 Gadus morhua ENSGMOG00000014154 9785 Loxodonta africana ENSLAFG00000014055
9315 Macropus eugenii ENSMEUG00000006640 30608 Microcebus murinus ENSMICG00000011988
59463 Myotis lucifugus ENSMLUG00000012050 61853 Nomascus leucogenys ENSNLEG00000011444
9978 Ochotona princeps ENSOPRG00000008312 9813 Procavia capensis ENSPCAG00000010107
13735 Pelodiscus sinensis ENSPSIG00000015138 132908 Pteropus vampyrus ENSPVAG00000003876
42254 Sorex araneus ENSSARG00000014229 43179 Ictidomys tridecemlineatus ENSSTOG00000006691
37347 Tupaia belangeri ENSTBEG00000009608 59729 Taeniopygia guttata ENSTGUG00000002572
99883 Tetraodon nigroviridis ENSTNIG00000011707 31033 Takifugu rubripes ENSTRUG00000015454
9739 Tursiops truncatus ENSTTRG00000007155 30538 Vicugna pacos ENSVPAG00000005450
8364 Xenopus tropicalis ENSXETG00000000836 8083 Xiphophorus maculatus ENSXMAG00000005165
8090 Oryzias latipes ENSORLG00000014335 7757 Petromyzon marinus ENSPMAG00000009008