Bioinformatics.org
[OMICtools]
[Repositive.io]
Not logged in
  • Log in
  • Bioinformatics.org
    Membership (40180+) Group hosting [?] Wiki
    Franklin Award
    Sponsorships

    Careers
    About bioinformatics
    Bioinformatics training
    Bioinformatics jobs

    Research
    All information groups
    Online databases Online analysis tools Online education tools More tools

    Development
    All software groups
    FTP repository
    SVN & CVS repositories [?]
    Mailing lists

    Forums
    News & Commentary
  • Submit
  • Archives
  • Subscribe

  • Jobs Forum
    (Career Center)
  • Submit
  • Archives
  • Subscribe
  • Career Center - News

    Featured announcements

    Submit a job announcement | Summary view of positions by date | Subscribe or unsubscribe

    Latest announcements
    Submit Archive Subscribe

    Submitter

    BACKGROUND

    Paramount are working in partnership with Genomics England to expand their team in order to deliver success with the 100,000 Genomes Project. This is a challenging and fast moving project with the aim to carry out whole genome sequencing on 100,000 participants. Genomics England works with key partners to collect, transport, store, quality check and sequence the samples from participants. The aim for this project is to create a new genomic medicine service for the NHS – transforming the way people are cared for. Patients may be offered a diagnosis where there wasn't one before. In time, there is the potential of new and more effective treatments.

    The post holder is an experienced senior bioinformatician with software development experience to lead a small team to deliver challenging 'build' objectives.

    RESPONSIBILITIES

    • Lead a team of approx. four developers to build cutting edge systems for clinical interpretation
    • Produce high quality code
    • Liaise with internal and external parties to determine platform requirements
    • Maintain in-house capability to analyse WGS data of patients with cancer or rare diseases and conducts interpretation of findings
    • Perform computational analyses for a range of projects
    • Implement programmes for high-throughput sequencing data analysis
    • Establish general bioinformatics resources for day-to-day use by colleagues
    • Contribute to the wider team's continuous improvement efforts

    REQUIREMENTS

    • Team leadership expertise
    • Experience of working as a computational biologist, delivering bioinformatics database solutions
    • MSc or PhD (or equivalent experience) in Biology or related discipline
    • Python coding experience
    • Proficient in Java programming is desirable.
    • Solid skillset in Bioinformatics
    • Solid exposure to Linux, Git, Postgres (or similar)
    • Several years' experience of developing algorithms and software to analyse large data sets
    • Experience developing non-relational database systems (eg Mongo, Hadoop)
    • A demonstrable ability to cope under pressure and deliver to deadlines
    • Ability to communicate effectively within a multidisciplinary team
    • Flexible and co-operative approach to colleagues
    • Ability to work independently and to show initiative within a team
    • Ability to prioritise and balance competing demands
    • Excellent technical writing skills
    • Ability to work independently and to show initiative within a team
    • Ability to prioritise and balance competing demands

    COMPENSATION

    There are some great benefits on offer with this role including a competitive salary, pension, generous holidays and more.

    HOW TO APPLY

    Please do not hesitate to contact Harvey Uppal at huppal[at]pararecruit.com or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Lead, Bioinformatics, Genomics, WGS, Cancer, Rare Disease, Python, Java, PostgreSQL, Algorithm, RDBMS, MongoDB, Linux, Database, London.

    Submitter

    BACKGROUND

    Paramount are working in partnership with Genomics England to expand their team in order to deliver success with the 100,000 Genomes Project. This is a challenging and fast moving project with the aim to carry out whole genome sequencing on 100,000 participants. Genomics England works with key partners to collect, transport, store, quality check and sequence the samples from participants. The aim for this project is to create a new genomic medicine service for the NHS – transforming the way people are cared for. Patients may be offered a diagnosis where there wasn't one before. In time, there is the potential of new and more effective treatments.

    RESPONSIBILITIES

    This role is based in the Cambridge High Performance Computing Service, although there will be occasional London based working. The post holder is an experienced software developer, with exposure to bioinformatician approaches, responsible for creating web applications, producing high quality code and utilising programming skills for the interpretation of genetic data from large databases.

    Accountabilities:
    • Produces high quality code
    • Liaises with internal and external parties to determine platform requirements
    • Assists with the deployment, maintenance and troubleshooting of computational pipelines for WGS processing and analysis
    • Performs quality assurance of the analysis and annotation made by third parties.

    REQUIREMENTS

    • Degree in a quantitative discipline such as computer science, biology, physics or mathematics, or experience to a similar level
    • Proven track record of developing high quality applications/systems with web services and user interfaces
    • Extensive experience with web technologies such as HTML5, JavaScript (ES6), CSS, AJAX, Node, NPM, JQuery
    • Good experience with some web frameworks such as Google Polymer, Bootstrap, Angular, Foundation
    • Knowledge of Java, Python, MongoDB is desirable.
    • Competent at developing APIs, and working with RESTful APIs
    • Experienced with distributed systems
    • Solid exposure to Linux, Git, GitHub, Apache HTTP and Tomcat servers
    • Proficiency in collaborative development tools such as Github, Confluence and JIRA
    • Comfortable using of high performance computing clusters
    • A demonstrable ability to cope under pressure and deliver to deadlines
    • Flexible and co-operative approach to colleagues
    • Ability to work independently and to show initiative within a team
    • Ability to prioritise and balance competing demands
    • Good attention to detail
    • Some exposure to bioinformatics is desirable.
    • Experience of working on greenfield projects is desirable.

    COMPENSATION

    There are some great benefits on offer with this role including a competitive salary, pension, generous holidays and more.

    HOW TO APPLY

    Please do not hesitate to contact Harvey Uppal at huppal[at]pararecruit.com or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Web, Developer, Front End, Genomics, Bioinformatics, JavaScript, HTML, CSS, Node.JS, Restful, API's, Linux, Github, Java, Python, HPC, Cambridge.

    BACKGROUND

    A postdoctoral position is immediately available in Dr. Sushmita Roy's research group to develop and apply computational methods to build genome-scale cell type-specific predictive regulatory networks in mammalian developmental lineages with a focus on neuronal cell types. This position entails integrating published and novel transcriptional and epigenomic datasets from bulk and single cell omic data to construct cell type-specific regulatory networks and generate prioritized predictions that will be tested in collaboration with experimentalists. The postdoc will be working in close collaboration with developmental biologists and stem cell engineers at the Wisconsin Institute for Discovery as well as neurobiologists at the Waisman center, UW Madison.

    RESPONSIBILITIES

    The Roy lab's research focuses on computational network biology and regulatory genomics. We are specifically interested in developing tools, based on statistical machine learning, to predict regulatory network structure and function in diverse dynamic processes. We aim to use these genome-scale networks to construct predictive models of complex phenotypes in mammalian systems. We work in close collaboration with developmental biologists who are interested in how gene regulatory networks drive overall cellular fate and are able to test model predictions as well as to generate new datasets to improve regulatory network reconstruction.

    REQUIREMENTS

    Either a PhD in computer science, statistics, machine learning with an interest to learn about genomic data analysis, OR, a PhD in computational biology, bioinformatics, with papers in leading computational biology venues.

    LOCALE

    The Roy lab is situated in the Wisconsin Institute for Discovery (WID). The WID, established in 2010, has state of the art research and computing infrastructure and was voted the 2012 Laboratory of the Year. WID offers a unique interdisciplinary and highly collaborative environment bringing together scientists spanning broad computational and biological disciplines including epigenetics, systems biology, optimization and stem cell engineering. Madison, WI.

    HOW TO APPLY

    To apply, please send (1) CV with publications, (2) statement of research describing current research and future goals, and, (3) contact information of three references. Please send this information to sroy[at]biostat.wisc.edu.

    RESPONSIBILITIES

    Performs routine patient care functions such as physician assistance, patient check-in and placement in room, testing, information gathering, answering patient calls/documenting notes, chaperoning, supply maintenance, scheduling, and conflict resolution. Prepares and maintains treatment rooms for patient examinations. Interviews and records patient's/participant's medical history, vital statistics, and other medical information. Cleans and sterilizes instruments and disposes of contaminated supplies. Prepares and administers medications, injections, or treatments, obtains and prepares specimens for lab tests as directed by the physician or other health care provider. May operate and maintain equipment to administer routine diagnostic tests. Coordinates with external medical facilities. Assists with prior authorizations and other patient support as needed. Draws blood on patients/participants as needed medical care or for clinical trials. Schedules appointments, maintains medical records, and completes paperwork. Performs accurate, legal, and ethical documentation at all times. Inputs patient/participant data into disease-specific database. Performs other duties as assigned.

    REQUIREMENTS

    Minimum Qualification:
    High school diploma or GED and a certified Medical Assistant with 1 year of relevant experience or combination. Documentation of phlebotomy training and skills required.

    Must have experience with data entry, managing patient files and records, medical terminology, and equipment sterilization procedures. Must be detail oriented, flexible, adaptive, and have excellent communication skills. Must have the ability to deal professionally with diverse personalities and cultures in stressful and difficult situations. Must maintain confidential information and keep up-to-date technically. Must have ability to multi-task, work independently and as a team player.

    Preferred Qualifications:
    Very skilled Phlebotomist with previous exposure to research environment and experience with clinical trials a plus.

    Bilingual (Spanish) a plus.

    TERMS

    Work Hours:
    Typically Monday through Friday, 8:30am-5pm however hours may very with advanced notice depending on work load and need for office coverage.

    Physical Demands:
    Regularly required to move about the clinic, talk, listen, use manual dexterity, and reach with hands and arms. Occasionally required to sit, stoop, kneel and lift or move up to 20 pounds. Vision requirements include close vision and ability to adjust focus. Occasionally exposed to viruses and other health related risks from patients/participants. Potential for electrical shock. The noise level is usually moderate.

    COMPENSATION

    We offer attractive salaries & comprehensive benefits package.

    HOW TO APPLY

    Interested applicants should apply online at apptrkr.com/1228631

    BACKGROUND

    Boehringer Ingelheim is an equal opportunity global employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment which benefits our employees, patients and communities.

    Are you looking for a new challenge in a globally successful pharmaceutical company in its research department Target Discovery Research? You are interested in exploring and analyzing data for early drug discovery? Then please apply for our open vacancy "Data Scientist Early Drug Discovery".

    TASKS & RESPONSIBILITIES

    • As data scientist you drive data vision, explore and prototype data-driven features for central applications supporting early drug discovery.
    • You integrate data from different domains and sources in a reproducible and actionable fashion.
    • In addition, you develop and implement concepts to ensure data quality and consistency.
    • With your expertise in data science, you develop robust long-term update strategy for internal and external data sources.
    • One of your key tasks and responsibilities is the development and implementation of a data strategy for early drug discovery.

    REQUIREMENTS

    • PhD in Data Science, bioinformatics or a related area
    • Profound know-how on data for drug discovery, incl genetics, transcriptomics, proteomics, biochemical, biophysical, protein data, patient, pathway and network data
    • Know-how and practical experience (design and coding) in integrating data from heterogeneous public domain, commercial and proprietary data
    • Familiarity with ontologies, nomenclatures, metadata concepts as well as cloud computing , NoSQL databases, SQL, Python, R
    • Know-how in analytics and machine learning, including analysis of unstructured data
    • Fluent spoken and written English
    • Collaborative, creative, solution oriented, and willing to work in an agile environment and to accept uncertainties, able to develop and drive strategies

    ABOUT US

    Innovative medicines for people and animals have for more than 130 years been what the research-driven pharmaceutical company Boehringer Ingelheim stands for. Boehringer Ingelheim is one of the pharmaceutical industry's top 20 companies and to this day remains family-owned. Day by day, some 50,000 employees create value through innovation for the three business areas human pharmaceuticals, animal health and biopharmaceutical contract manufacturing. In 2016, Boehringer Ingelheim achieved net sales of around 15.9 billion euros. With more than three billion euros, R&D expenditure corresponds to 19.6 per cent of net sales.

    HOW TO APPLY

    Please submit your application online: tas-boehringer.taleo.net/care[...]ng=en

    For further information please contact Recruiting Services:
    Mrs. Yue Pan, Tel: +49 (0) 7351 54 188546

    Not exactly the position you are looking for? You can still forward it to friends or colleagues who might be interested. Please use the "share" button at the bottom of the page.

    POLICY

    Boehringer Ingelheim is an equal opportunity employer who takes pride in maintaining a diverse and inclusive workplace. We embrace all aspects of diversity and inclusion which benefit our employees, patients and communities. We look forward to receiving your online application!

    BACKGROUND

    A Postdoctoral Research Associate position is available in the Division of Epidemiology, Department of Medicine, from Vanderbilt University Medical Center. Our current research concentrates on population-based genetic epidemiologic studies for the exploration of putative causative genetic risk variants and genes for cancers using bioinformatic and functional genomics approaches. We will focus on numerous genetic epidemiology and large genomics studies using large population-based prospective cohort studies. We will apply and develop bioinformatics tools and build statistical models to process large whole genome sequencing and whole exome sequencing, RNA-seq, array-based genotype and epigenetic data to investigate all types of genetic variants including coding/noncoding and structure variants for understanding the underlying molecular mechanisms of cancerigenesis. The successful candidate will lead independent research projects in genetics, epigenetics, functional genomics, and bioinformatics fields. The successful candidate will also expect to participate in multiple collaborative projects in cancer-related genetic epidemiology studies.

    RESPONSIBILITIES

    Under guidance from Dr. Xingyi Guo, the candidate is expected to work in a wide range of bioinformatics projects.

    REQUIREMENTS

    • PhD in bioinformatics, computational biology, biostatistics, genomics, molecular biology or related fields. The successful candidate should have strong background in processing high-throughput genomic and genetic data with biostatistics knowledge.
    • Strong experience with script languages such as Perl, Python or R and the Linux/Unix environment is required.
    • Experience in statistical computing (e.g. R/Bioconductor and Biopython)
    • Good interpersonal skills
    • Excellent in English both in writing and speaking

    COMPENSATION

    Salary is commensurate according to the NIH pay level. The postdoc positions will be provided with the benefits following Vanderbilt University Medical Center standard.

    ABOUT US

    The Division of Epidemiology is committed to conducting research to enhance and expand our understanding of the distribution and determinants of disease, to promoting collaboration aimed at the translation of research into cost-effective strategies of disease prevention and health care delivery, and to training independent investigators in epidemiology research and disease prevention. Our group has a broad interest in the research of genetics and genomics for cancer studies. We concentrate on population-based genetic epidemiologic studies for the exploration of novel genetic risk variants and genes for cancer outcomes. These projects will primarily build from valuable cohort resources based at the Vanderbilt Epidemiology Center, i.e., the Asian Breast Cancer Consortium (ABCC) and the Asia Colorectal Cancer Consortium (ACCC). We are interested in developing and applying computational methods for processing high-throughput genomic sequencing data from the above population-based cohorts to identify various genetic variants, especially structure variants for cancer risk. In particular, we are also highly interested in studying the functional potential of risk coding or noncoding variants by integrated big experimental data from next-generation sequencing (e.g., ChIP-seq, ATAC-seq, BS-seq and RNA-seq) from public databases (i.e. ENCODE). Information about the Division of Epidemiology can be found at medicineandpublichealth.vanderbilt.edu/vec/[...]x.php.

    HOW TO APPLY

    To apply, please send cover letter, CV, summary of past work, and the names and email addresses of three references to Dr. Xingyi Guo at xingyi.guo[at]vanderbilt.edu. The position will be for two years with the possibility of further extension.

    DEADLINE

    The deadline for applications is July 30, 2018. Any applications received after this time or incomplete will not be considered.

    POLICY

    Vanderbilt University Medical Center wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background.

    Submitter

    BACKGROUND

    Paramount are working in partnership with Genomics England to expand their team in order to deliver success with the 100,000 Genomes Project. This is a challenging and fast moving project with the aim to carry out whole genome sequencing on 100,000 participants. Genomics England works with key partners to collect, transport, store, quality check and sequence the samples from participants. The aim for this project is to create a new genomic medicine service for the NHS – transforming the way people are cared for. Patients may be offered a diagnosis where there wasn't one before. In time, there is the potential of new and more effective treatments.

    RESPONSIBILITIES

    The post holder is an experienced bioinformatician with software development experience to work as part of the team responsible for pipeline delivery.

    Accountabilities:
    • Produces high quality code
    • Liaises with internal and external parties to determine platform requirements
    • Maintains in-house capability to analyse WGS data of patients with cancer or rare diseases and conducts interpretation of findings
    • Performs computational analyses for a range of projects
    • Implements programs for high-throughput sequencing data analysis
    • Establishes general bioinformatics resources for day-to-day use by colleagues
    • Contributes to the team's continuous improvement efforts

    REQUIREMENTS

    • MSc or PhD (or equivalent experience) in Biology or related discipline. Preferably with a Post doctorate and several years' experience of working in this field
    • Experience of working as a computational biologist, delivering bioinformatics database solutions
    • Good Python coding skillset
    • Solid skillset in Bioinformatics
    • Good exposure to Linux, Git, Postgres (or similar)
    • Solid expertise of developing algorithms and software to analyse large data sets
    • A demonstrable ability to cope under pressure and deliver to deadlines
    • Ability to communicate effectively within a multidisciplinary team
    • Flexible and co-operative approach to colleagues
    • Ability to work independently and to show initiative within a team
    • Ability to prioritise and balance competing demands.
    • Excellent technical writing skills

    COMPENSATION

    There are some great benefits on offer with this role including a competitive salary, pension, generous holidays and more.

    HOW TO APPLY

    Please do not hesitate to contact Harvey Uppal at huppal[at]pararecruit.com or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Senior, Bioinformatics, Genomics, London, WGS, Rare Disease, Cancer, Python, Linux, PostgreSQL, Algorithm, Database, Analysis.
    Opportunity: Bioinformatician @ Genomics England -- Cambridge, UK
    Submitted by Eugene Mc Daid; posted on Thursday, May 24, 2018

    Submitter

    BACKGROUND

    Paramount are working in partnership with Genomics England to expand their team in order to deliver success with the 100,000 Genomes Project. This is a challenging and fast moving project with the aim to carry out whole genome sequencing on 100,000 participants. Genomics England works with key partners to collect, transport, store, quality check and sequence the samples from participants. The aim for this project is to create a new genomic medicine service for the NHS – transforming the way people are cared for. Patients may be offered a diagnosis where there wasn't one before. In time, there is the potential of new and more effective treatments.

    RESPONSIBILITIES

    This post holder will support the Development and Demonstration activities of Genomics England through the comprehensive analysis of (largely) sequence data sets from a variety of platforms. The position is based in Cambridge with some London based working required.

    Accountabilities:
    • Performing computational analyses for a range of D &D projects
    • Comparing tools and pipelines for NGS analysis
    • Informing on the design and implementation of new features for sequencing data analysis

    REQUIREMENTS

    • MSc or PhD in Bioinformatics or related discipline (or equivalent expertise)
    • Solid skillset in Bioinformatics and experience of working as a computational biologist
    • Practical knowledge of NGS algorithms and available resources for cancer bioinformatics
    • Experience of comparing NGS data sets
    • Experience with handling large data sets and setting pipelines
    • Strong programming skills (Python, R); ability to develop codes as a part of team
    • Practical knowledge and understanding of basic statistical tests
    • A demonstrable ability to cope under pressure and deliver to deadlines
    • Ability to communicate effectively within multidisciplinary teams and with others from other non bioinformatic disciplines
    • Flexible and co-operative approach to colleagues
    • Ability to work independently and to show initiative within a team
    • Ability to prioritise and balance competing demands

    COMPENSATION

    There are some great benefits on offer with this role including a competitive salary, pension, generous holidays and more.

    HOW TO APPLY

    Please do not hesitate to contact Harvey Uppal at huppal[at]pararecruit.com or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Bioinformatics, Genomics, NGS, Algorithm, Statistics, Python, R, Pipelines, Cambridge, London.

    Submitter

    BACKGROUND

    Paramount are working in partnership with Genomics England to expand their team in order to deliver success with the 100,000 Genomes Project. This is a challenging and fast moving project with the aim to carry out whole genome sequencing on 100,000 participants. Genomics England works with key partners to collect, transport, store, quality check and sequence the samples from participants. The aim for this project is to create a new genomic medicine service for the NHS – transforming the way people are cared for. Patients may be offered a diagnosis where there wasn't one before. In time, there is the potential of new and more effective treatments.

    RESPONSIBILITIES

    This role's main purpose is to ensure the smooth operations of the bioinformatics pipeline in accordance with ISO 15189 standards.

    Leading a team of ~4 people, you will be responsible for the day to day running of the results pipeline, updating senior and external stakeholders on the status of the pipeline and reporting to the quality team.

    Accountabilities:
    • Monitoring delivery, operational trouble shooting and implementing sustainable continuous improvements that drive successful KPI delivery
    • Contributing to the development and execution of the operational pipeline line strategy, roadmap and operational objectives, KPIs and resource and budget plans
    • Leading a team to ensure the day to day running of the operations pipeline
    • Ensuring that the reporting of the bioinformatics pipeline status is up to date and dashboards are updated. Producing weekly report on KPIs for the ISO 15189 standard
    • Representing Bioinformatics operations at key quality and team reviews
    • Interfacing with operations teams within other functions across Genomics England to ensure the smooth running of the pipeline
    • Working to continuously improve the operations process and to promote a quality culture
    • Ensuring Service desk tickets are responded to by the team in a timely manner
    • Maintaining service desk ticket backlog

    REQUIREMENTS

    • Essential to have knowledge of working within an ISO accredited lab (preferably ISO 15189 or ISO17025).
    • Strong record of leadership and multiple stakeholder groups while under tight timelines
    • Solid expertise of using Continuous Improvement methods in an operational setting to achieve operational objectives
    • Proven expertise in using performance metrics to drive results
    • Experience of trouble shooting and operational problem resolution (eg root cause analysis)
    • Exposure to Lean processing is desirable.
    • Desirable to have knowledge of JIRA and Confluence.
    • Experience responding to service desk enquires and external customer enquires desirable.
    • Experience running operations in a large company or laboratory
    • Data management, operational and scientific problem-solving skills
    • Report writing, analytical and reporting skills
    • Must have demonstrated excellent ability to interface with customers and internal teams.
    • Be able to work cross-functionally through many teams to execute goals and set and meet milestones.
    • Proven team management and people development expertise
    • Basic understanding of genetics, sequencing and bioinformatics is desirable.
    • Strong organisational, time management and planning skills
    • Self-motivated, with excellent ability to work on own initiative
    • Excellent team-working skills with willingness and ability to engage with others at all levels of the organisation
    • Ability to analyse information and present it in a clear, concise way to clinical, scientific, and corporate audiences
    • Ability to work under pressure without compromising the quality of work
    • Excellent written and interpersonal skills

    COMPENSATION

    There are some great benefits on offer with this role including a competitive salary, pension, generous holidays and more.

    HOW TO APPLY

    Please do not hesitate to contact Harvey Uppal at huppal[at]pararecruit.com or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Operations, Performance, Manager, ISO, Leadership, Jira, Confluence, Bioinformatics, Genomics, Data Management, London.

    Submitter

    BACKGROUND

    Paramount are working in partnership with Genomics England to expand their team in order to deliver success with the 100,000 Genomes Project. This is a challenging and fast moving project with the aim to carry out whole genome sequencing on 100,000 participants. Genomics England works with key partners to collect, transport, store, quality check and sequence the samples from participants. The aim for this project is to create a new genomic medicine service for the NHS – transforming the way people are cared for. Patients may be offered a diagnosis where there wasn't one before. In time, there is the potential of new and more effective treatments.

    RESPONSIBILITIES

    The post holder's primary role is the curation of genetic variants from databases, submitted expert lists and the literature, the assessment of evidence for genes involved in rare diseases and cancer and the evaluation of clinically-actionable information.

    They will work closely with other Curators, Clinical Geneticists and Bioinformaticians within Genomics England to deliver curation requirements to deadlines, and interact with experts across the UK and internationally to gain review of genes or genetic variants.

    Ultimately, their work will contribute to the Genomics England genome interpretation pipeline and aid the reporting of diagnoses or clinically actionable information for patients as part of this team effort.

    Accountabilities:
    • Contributing to the Curation Team effort and supporting the needs of the Bioinformatics Team
    • Delivery of assigned curation requirements within deadlines
    • Interaction with experts in the assigned disease field for review of genes or variants in a professional manner
    • Support the promotion, development, updates and data curation of PanelApp (panelapp.genomicsengland.co.uk).

    REQUIREMENTS

    • BSc or higher in genetics, biological sciences or equivalent, and an in-depth understanding of genetic variation and genomics
    • Solid curation experience, with a strong background in genetics and human disease
    • Ability to efficiently query databases and carry out data comparisons
    • Exposure to mapping genetic variants to reference sequences and standardised variant nomenclature
    • Experience extracting, interpreting and annotating published scientific papers
    • Able to use standardised terms and ontologies for variants, genes, phenotypes
    • Proven ability to utilise databases, adding information to databases and use of curation tools
    • Experience of using genetic and disease-based databases
    • Ability to prepare reports and publications
    • Strong written and oral English communication skills
    • Good computer skills, including word processing and spreadsheet applications
    • Ability to understand scientific literature, experimental procedures, current genomics projects
    • Attention to detail
    • Ability to communicate effectively within a multidisciplinary team
    • Flexible and co-operative approach to colleagues
    • A demonstrable ability to cope under pressure and deliver to deadlines

    PREFERENCES

    • Ability to write code to query databases and carry out data comparisons.
    • Background in cancer and/or human rare diseases.
    • Knowledge of pharmacogenomics.
    • Clinical genetics background.
    • Experience in the curation of scientific knowledge for the interpretation of human genomes.

    COMPENSATION

    There are some great benefits on offer with this role including a competitive salary, pension, generous holidays and more.

    HOW TO APPLY

    Please do not hesitate to contact Harvey Uppal at huppal[at]pararecruit.com or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Scientific, Curator, Clinical, Geneticist, Bioinformatics, Genomics, Database, Variants, Annotating, Cambridge, London.

    Submitter

    BACKGROUND

    A successful Biotech based in the Cambridge area is currently seeking an established Bioinformatician to lend computational expertise to the company, contributing the development of innovative new cancer treatments. Using cutting edge scientific research, they strive to create new therapeutics that will minimise damage to healthy tissue and eliminate the debilitating side effects that can incur with today's cancer treatments.

    RESPONSIBILITIES

    This will be a Lead Bioinformatician role, and the position is responsible for:
    • Building and supporting all Bioinformatics for the company
    • Working closely with key research collaborations
    • Performing target and biomarker validation, and disease linkage
    • Summarize scientific results and present clear conclusions
    • Develop new bioinformatics tools, approaches and infrastructure

    REQUIREMENTS

    The ideal candidate will have:
    • A PhD or equivalent experience in Bioinformatics and Computational Biology
    • A strong scientific understanding of cancer genomics/drug discovery
    • Strong technical ability, proficient with Perl or Python, and familiar with a linux environment
    • Expert in statistical analysis of genomic data
    • Data visualisation skills
    • A knowledge of the drug discovery process or previous experience in target identification/validation is highly desirable
    • Good communication skills

    HOW TO APPLY

    This is an exciting and challenging opportunity to develop a Bioinformatics department within an established organisation, contributing to vital research into cancer therapy. For more information on this position, send your CV to efrancis[at]pararecruit.com. For an informal chat about this and the many other exciting Bioinformatics opportunities we have available, call Emilie on 0121 616 3477.

    Key words: Cancer, Oncology, Bioinformatician, Drug Development, Translational, Drug Discovery, Target identification, Biomarker discovery, Computational Biologist, Computational Biology, Bioinformatics, Genomics, Biotech

    Submitter

    BACKGROUND

    100,000 Genomes Project – Bioinformatics – Central London OR Cambridge!

    Paramount are working in partnership with Genomics England to expand their team in order to deliver success with the 100,000 Genomes Project. This is a challenging and fast moving project with the aim to carry out whole genome sequencing on 100,000 participants.

    A fantastic new opportunity has become available for a Scientific Curator to join their highly motivated Bioinformatics Curation team, working closely with other Curators, Clinical Geneticists and Bioinformaticians within Genomics England to deliver curation requirements to deadlines, and interact with experts across the UK.

    Your work will contribute to their genome interpretation pipeline and aid the reporting of diagnoses or clinically actionable information for patients.

    RESPONSIBILITIES

    Your main responsibilities as a Curator will be:
    • Curating genetic variants from databases, submitted expert lists and the literature
    • Assessing evidence for genes involved in rare diseases and cancer and evaluating clinically actionable information
    • Contributing to the Curation Team effort and supporting needs of the Bioinformatics Team
    • Delivering assigned curation requirements within deadlines
    • Interacting with experts in the assigned disease field for review of genes or variants
    • Supporting the promotion, development, updates and data curation of PanelApp

    REQUIREMENTS

    The ideal Scientific Curator should meet the following requirements:
    • Educated at BSc or higher in Genetics, Biological Sciences or equivalent
    • In-depth understanding of and experience in genetic variation and genomics
    • Solid curation experience (3-5 years), with a strong background in Genetics and Human Disease
    • Able to efficiently query databases and carry out data comparisons
    • Exposure to mapping genetic variants to reference sequences and standardised variant nomenclature
    • Experience extracting, interpreting and annotating published scientific papers
    • Experience of using genetic and disease-based databases, adding information and using curation tools using standardised terms and ontologies for variants, genes, and phenotypes

    ABOUT US

    Genomics England works with key partners to collect, transport, store, quality check and sequence the samples from participants. The aim for this project is to create a new genomic medicine service for the NHS – transforming the way people are cared for. Patients may be offered a diagnosis where there wasn't one before. In time, there is the potential of new and more effective treatments.

    COMPENSATION

    You'll be able to work in their brand new offices in Central London and in return you will receive competitive salary and have the opportunity to work within a successful company in a fantastic location.

    HOW TO APPLY

    If you'd like to know more and are interested in applying, please contact Anna on alauterjung[at]pararecruit.com or +44 (0) 121 616 3469 with an up-to-date CV. Look forward to hearing from you!

    Keywords: Scientific Curator, Curator, Database, Human Genetics, Rare Disease, Cancer, genetic variants, clinical, PanelApp, curation, query, Biology, Biological Sciences, Human Disease, mapping variants, Bioinformatics, London, UK
    Opportunity: Bioinformatician @ Genomics England -- London, UK
    Submitted by Eugene Mc Daid; posted on Monday, May 21, 2018

    Submitter

    BACKGROUND

    100,000 Genomes Project – Bioinformatics – Central London!

    Paramount are working in partnership with Genomics England to expand their team in order to deliver success with the 100,000 Genomes Project. This is a challenging and fast moving project with the aim to carry out whole genome sequencing on 100,000 participants.

    A fantastic new opportunity has become available for a Bioinformatician to join their highly motivated Bioinformatics Interpretation team which is responsible for pipeline delivery. This role is ideal for a strong Bioinformatician with Software development experience (preferably Python).

    RESPONSIBILITIES

    Your main responsibilities as a Bioinformatician will be:
    • Producing high quality code
    • Liaising with internal and external parties to determine platform requirements
    • Maintaining in-house capability to analyse WGS data of patients with cancer or rare diseases and conducts interpretation of findings
    • Performing computational analyses for a range of projects
    • Implementing programs for high-throughput sequencing data analysis
    • Establishing general bioinformatics resources for day-to-day use by colleagues

    REQUIREMENTS

    The ideal Bioinformatician should meet the following requirements:
    • Educated at MSc or PhD (with equivalent experience) in Bioinformatics/Computational Biology or related discipline
    • Preferably Postdoc and several years' experience working as a Computational Biologist/Bioinformatician, delivering bioinformatics database solutions
    • Good Python coding skillset
    • Good exposure to Linux, Git, Postgres or similar technologies
    • Solid expertise of developing algorithms and software analysing large datasets

    COMPENSATION

    You'll be able to work in their brand new offices in Central London and in return you will receive competitive salary and have the opportunity to work within a successful company in a fantastic location.

    ABOUT US

    Genomics England works with key partners to collect, transport, store, quality check and sequence the samples from participants. The aim for this project is to create a new genomic medicine service for the NHS – transforming the way people are cared for. Patients may be offered a diagnosis where there wasn't one before. In time, there is the potential of new and more effective treatments.

    HOW TO APPLY

    If you'd like to know more and are interested in applying, please contact Anna on alauterjung[at]pararecruit.com or +44 (0) 121 616 3469 with an up-to-date CV. Look forward to hearing from you!

    Keywords: Bioinformatician, Computational Biologist, Bioinformatics, Pipeline, Software, Python, Coding, Linux, Git, Postgres, MongoDB, NGS, WGS, Whole genome sequencing, PhD, MSc, variant calling, Postdoc, Database, UK, London

    BACKGROUND

    The hosting research group works on several aspects of genomics and molecular evolution, typically developing or applying models or methods to address biological questions of interest. Recent work has included development of methods to detect genetic variants affecting germline mutation rates from haplotype data, algorithms for the analysis of deep sequencing data from the T cell receptors and immunoglobulins and the development and application of methods and computational tools to disentangle the effects of cell type composition and gene expression variation in biological samples consisting of mixtures of different cell types. The group is located in the School of Mathematics, Statistics and Applied Mathematics at NUI Galway and is part of the Bioinformatics and Biostatistics Research Cluster (maths.nuigalway.ie/biocluster/).

    RESPONSIBILITIES

    This project will involve modeling somatic mutation processes, including sources of variation across the genome, between individuals in populations or between species. The successful applicant will be capable of working as part of the project team, which will include four PhD students, and of helping to guide and develop the research programme. The applicant will develop models, write computer code and analyze data and will be expected to produce publication quality scientific outputs.

    REQUIREMENTS

    The applicant must have a PhD in Bioinformatics/Computational Biology, Statistics/Data Science, Mathematics or Computer Science or a PhD in the life sciences with evidence of substantial expertise and experience in statistics and computing. Applicants should have published their work in high-quality international journals, or have work that is in the process of publication. Good communication and leadership skills and the capacity both to work independently and to motivate and help others are essential.

    TERMS

    This is a full-time position for three years.

    LOCALE

    This position will be based in the School of Mathematics, Statistics and Applied Mathematics, National University of Ireland Galway. Biomedical research is a major strategic focus of the university and of the industries in its hinterland and the university is highly ranked in the mathematical sciences. Galway is welcoming city, located on the west coast of Ireland, with many attractions, particularly for those with interests in cultural or outdoor pursuits.

    COMPENSATION

    €40,000 - €44,000, depending on experience.

    HOW TO APPLY

    Applications should include an academic CV and a brief covering letter and should be sent by email to Cathal Seoighe (Cathal.Seoighe a t nuigalway.ie).

    DEADLINE

    June 29, 2018.

    Late applications will be considered if the position has not been filled. Feel free to get in touch for enquiries or to find out more about the position.

    BACKGROUND

    The University of Applied Sciences Weihenstephan-Triesdorf (HSWT) is characterized by a "green", innovative and hands-on approach to teaching and learning. No other university offers a similar range of courses in the life sciences with over 6,400 students at three locations (Freising, Triesdorf, Straubing).

    The Chair of Bioinformatics headed by Prof. Dr. Dominik Grimm, located at the TUM Campus Straubing for Biotechnology and Sustainability, Germany, offers the following full-time position.

    RESPONSIBILITIES

    • You will develop computational, statistical and machine-learning based methods for performing genome-wide association studies and for analyzing large collection of biological images.
    • You will develop and enhance cloud-based applications for bio(-medical) data.
    • You will apply and develop computational tools for analyzing Next Generation Sequencing (NGS) data.
    • You will write scientific publications and present your results at international conferences.
    • Additionally, you will assist in teaching as well as in writing proposals for fund raising for new research projects.

    REQUIREMENTS

    Your Profile:
    • Strong academic background and University degree (Master or Diploma) in bioinformatics, computer science, statistics, physics or related field
    • Experience and interest in several of the following areas: bioinformatics, machine learning, artificial neural networks (deep learning), statistics or development of cloud-based applications
    • Strong programming background (e.g. Python, C/C++)
    • Scientific curiosity, ability to work in a team and self-motivated working style
    • Fluency in written and spoken English

    TERMS

    The position is limited to 3 years.

    The starting date will be at the earliest date possible.

    COMPENSATION

    Pay scale in accordance with the collective agreement for the public service (TV-L).

    If you are interested in this position, please apply directly to the online form on the homepage of the HSWT: www.hswt.de/stel[...]e=594 ("Apply for this job") until 22.06.2018 including a motivation letter, CV and copies of certificates (Bachelor, Master) or via email as a single PDF to Prof. Dr. Dominik Grimm: dominik.grimm[at]hswt.de.

    For further information please do not hesitate to contact:
    Prof. Dr. Dominik Grimm Ingrid Meindl
    09421/187-230 / dominik.grimm[at]hswt.de 094217187-271 / ingrid.meindl[at]hswt.de
    www.cs.tum.de/bioinformatik

    POLICY

    Severely disabled candidates are preferably employed in case of essentially equal suitability, competence and professional performance. Qualified female candidates are explicitly encouraged to apply for this position.
    Submit Archive Subscribe

     

    Copyright © 2018 · Scilico, LLC