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    BACKGROUND

    Living DNA is leading the way in delivering direct to to consumer DNA testing with true purpose. Based near Bath in the UK the company provides its services on a global basis and is actively expanding its team.

    RESPONSIBILITIES

    Living DNA is seeking a highly motivated individual to join our company in a hands on manner. The key task is developing, managing, and programming scalable bioinformatics pipelines to infer human ancestry and health-related information from SNP data.

    You will work closely with leading academic partners and our internal bioinformatics team to evolve algorithms that have been developed to calculate genetic ancestry, relationships and traits. Part of these methods and processes are unique and highly specialised offering a unique picture on individuals' genetic history. Both for ancestry and health trait determination, the position will also involve identification, selection and implementation of public and proprietary methods, as well as mining of genetic data.

    This is a commercial position where you will be responsible for the day-to-day running of the various pipelines, database and data management, as well as programming and development of new features.

    In addition to commercial aspects and being an essential part of an exciting development with public awareness, you will also have the opportunity to scientifically publish in collaboration with leading universities.

    REQUIREMENTS

    A candidate with skills in interfacing and project management who has 2+ years working experience would be great a great fit.

    Essential Technical experience needed:
    • Coding language of Python and preferably also java and C/C++
    • Experience analysing datasets and statistical tests with R
    • Familiarity with version control software such as GitHub
    • Extensive knowledge of Linux operating system
    • High performance Computing, such as Amazon Web Services
    • Working knowledge and interest in Statistical Genetics
    • Familiarity with version control software such as GitHub
    • Understanding databases such as experience with creating MySQL

    PREFERENCES

    Nice to have:
    • Management and Statistical Analysis of Big Data
    • Web development such as PHP, HTML
    • Working and knowledge of R Studio
    • Prior working with human population genetics and ancestry inference
    For clarification questions please email Martin Blythe a marting[at]livingdna.com.

    TERMS

    Permanent, 5-10 year funding secured with option to extend

    LOCALE

    Frome, Somerset, UK

    COMPENSATION

    In line with experience

    HOW TO APPLY

    Please visit dnaworldwide.peoplehr.net/Page[...]80286

    DEADLINE

    15th February 2016

    BACKGROUND

    The NICHD Division of Intramural Research (DIR) depends on advanced information technology (IT) infrastructure, bioinformatics, and computer technology to support its mission and research in more than 70 laboratories. Our goal is to establish a bioinformatics/IT group where science comes first and nothing is impossible.

    RESPONSIBILITIES

    The Office of the Scientific Director is seeking a bioinformaticist who will also serve as a leader for bioinformatics and IT programs in the NICHD DIR. This individual will lead a team directly focused on advanced bioinformatics as well as IT support. Responsibilities include researching, securing, custom designing, and applying cutting-edge bioinformatics solutions, products, and support, as well as representing the IT interests of the DIR to NICHD and NIH-wide committees and workgroups. The successful candidate will support a variety of biomedical computing needs, as well as conducting his or her own pioneering bioinformatics research.

    REQUIREMENTS

    The ideal candidate will have a doctoral degree (Ph.D., M.D., or equivalent) and a demonstrated record of accomplishment in scientific and research computing to support a scientific enterprise focused on biomedical research. The position, due to its cross-cutting nature, requires an individual who is highly collaborative, is comfortable tackling scientific computing interests in a scientifically diverse environment, has strong oral and written communication skills, can build and manage an effective and productive team, and keeps abreast of the most current technological advances in support of both scientific and business computing strategy. Knowledge of the following areas is highly desired: academic scientific culture, scientific computing solution development in the research and research administration space, information technology security principles, clinical and basic research data management strategies, high performance computing hardware and software systems, scientific- and data-driven computational approaches, and content management systems. More detailed information about the NICHD DIR may be found at www.nichd.nih.gov/abou[...].aspx

    LOCALE

    Division of Intramural Research (DIR)
    Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    National Institutes of Health
    Health and Human Services
    Bethesda, MD, USA

    HOW TO APPLY

    Applications for this position will be accepted from January 17, 2017 to January 27, 2017. Applicants need to submit a resume/curriculum vitae. A cover letter highlighting key qualifications, a summary stating the applicant's philosophy for supporting the scientific computing needs of a scientifically diverse community, a description of accomplishments in supporting scientific computing in a dynamic research setting, and names and addresses of three references are strongly recommended. Please submit application materials to nichddirsearch[at]mail.nih.gov.

    POLICY

    HHS, NIH, and NICHD are Equal Opportunity Employers.

    Applications from women, minorities, and persons with disabilities are encouraged.

    BACKGROUND

    At the Biotechnology Centre (BIOTEC) of the Technische Universität Dresden in Germany, the Research Group "Structural Bioinformatics" lead by Dr. M. Teresa Pisabarro is inviting applications for a Postdoc position working on computer simulation of biomacromolecular systems and rational engineering. (Research and Teaching Fellow subjected to personal qualification and remunerated according to salary group E 13 TV-L.)

    The position will be available from 01.04.2017 and is limited to 3 years with the possibility to be extended upon success. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz – WissZeitVG). The position aims at obtaining further academic qualification.

    RESPONSIBILITIES

    Suitable applicants will work on characterisation of structure-function relationships and computer-aided simulation of biomacromolecular systems as well as rational engineering in a multidisciplinary and highly collaborative environment. The successful candidate will be also involved in teaching (in English) in our Molecular Bioengineering and Nanobiophysics international Master Programmes.

    REQUIREMENTS

    Suitable candidates should have: a university and Ph.D. degree in -or related to- structural and computational biology/physics/chemistry; outstanding internationally recognized scientific accomplishments in the areas of structural and computational biology/chemistry; strong computational background; experience with molecular dynamics simulations of proteins, DNA and/or GAGs, and in particular with AMBER; high motivation to work in a multidisciplinary, international and highly collaborative environment in simulation of biomacromolecular systems and rational engineering; excellent writing and communication skills in English (German is not required to work in our group).

    LOCALE

    The Research Group "Structural Bioinformatics" and the BIOTEC are excellently equipped and provide outstanding working conditions in a very international environment. The group has also access to the supercomputing facilities of the TU Dresden (ZIH).For scientific details please refer to our group's web site: www.biotec.tu-dresden.de/rese[...].html.

    The TU Dresden is one out of eleven German Universities of Excellence: strong in research with excellent post-graduate programs particularly in biomedical research, physics, material science, electronics and informatics. As a progressive full-status university with 14 faculties it is the largest technical university in Germany. The Biotechnology Centre (BIOTEC) of the TU Dresden is an international and interdisciplinary institute focused on molecular bio-engineering, proteomics, genomics, biophysics, stem cells and computational biology.

    HOW TO APPLY

    Interested candidates should send their application and CV (including a description of past research activities, publications and names and e-mail addresses of three referees) as a single PDF until 15.03.2017 (stamped arrival date of TU Dresden applies) to: mayte[at]biotec.tu-dresden.de (Please note: we are currently not able to receive electronically signed and encrypted data.). Applications sent by regular post should be addressed to TU Dresden, BIOTEC, Research Group "Structural Bioinformatics", Dr. M. Teresa Pisabarro, Tatzberg 47/49, 01307 Dresden, Germany. Please submit copies only, as your application will not be returned to you.

    POLICY

    Applications from women are particularly welcome. The same applies to people with disabilities

    BACKGROUND

    The Department of Bioinformatics and Computational Biology at The University of Texas MD Anderson Cancer Center, Houston, Texas, USA is seeking a postdoctoral fellow. The individual will work on cutting edge cancer related research projects at one of the top ranked cancer hospitals in the World. MD Anderson Cancer Center has topped U.S. News & World Report's "America's Best Cancer Hospitals" ranking many times in the last several years. We offer a rich and creative environment where independent research is encouraged.

    RESPONSIBILITIES

    The work involves computational analysis and no wet lab experience is required. The candidate must be proficient in programming and writing scientific articles. The postdoctoral fellow will analyze data from a multitude of genomic platforms, including sequencing, RNA, miRNA and protein expression, DNA methylation, mutations and copy number variations. The work is not limited to one cancer type, but spans multiple cancers and involves a diverse range of bioinformatics analyses. We are especially involved in the prestigious project The Cancer Genome Atlas (TCGA), the largest cancer research project at the National Cancer Institute (NCI), and other new Center for Cancer Genomics projects from the NCI. The position promises participation in such high profile ventures.

    REQUIREMENTS

    PhD in any of the basic sciences. Candidates must be proficient in programming in languages such as R, Matlab, Perl, Python and/or Java/Java Script. Basic biology and statistics knowledge is expected.

    PREFERENCES

    An advanced understanding of cancer biology is not required, however, knowledge of genetics and cell biology is preferred.

    LOCALE

    Houston, Texas, USA

    COMPENSATION

    Very competitive salary and benefits.

    HOW TO APPLY

    Interested candidates may send an introductory email with an attached CV to Dr. Rehan Akbani at rakbani[at]mdanderson.org

    POLICY

    M. D. Anderson Cancer Center is an equal opportunity employer and does not discriminate on the basis of race, color, national origin, gender, sexual orientation, age, religion, disability or veteran status except where such distinction is required by law. All positions at The University of Texas M. D. Anderson Cancer Center are security sensitive and subject to examination of criminal history record information. Smoke-free and drug-free environment.

    DESCRIPTION

    The Center for Systems Biology Dresden (www.csbdresden.de) calls for applications for ELBE Postdoctoral fellowships in the fields of Bioinformatics and Computational Biology.

    ELBE fellows are fully funded for a duration of 1-3 years. The ELBE postdoc program fosters cross-disciplinary projects and provides an ideal springboard to an independent research career. Candidates should have a background in computer science, bioinformatics, or (applied) mathematics and a strong interest to work in a multi-disciplinary environment on Biological Sequence Analysis, Bioimage Informatics, Computer Simulation of biological systems, Comparative and Evolutionary Genomics, High-Performance Computing, or Network Biology.

    What we provide:
    The CSBD provides 1-3 year postdoc positions in an international and cross disciplinary research environment. ELBE fellows benefit from close collaborations with scientists at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), the Max Planck Institute for the Physics of Complex Systems (MPI-PKS), and the Technische Universität Dresden (TU Dresden) and from full access to state-of-the-art research facilities and infrastructure. ELBE fellows have the freedom to develop their own research questions. They obtain mentoring and support in their hosting groups. ELBE fellows may choose the research groups to be affiliated with. To foster collaboration, ELBE fellows are usually affiliated with two hosting groups working in different disciplines

    What we seek:
    We seek outstanding young researchers with a doctoral degree in computer science, mathematics, or bioinformatics and a strong commitment to work in a cross-disciplinary environment with biologists, computer scientists, and physicists.

    HOW TO APPLY

    For details about the application procedure, please visit our website www.csbdresden.de/educ[...]jobs/

    Selection of ELBE Fellows is highly competitive with two application cycles per year. Short-listed candidates are invited to on-site interviews with travel costs covered by the CSBD.

    DEADLINE

    Deadline for applications is March 3, 2017.

    POLICY

    The Max Planck Society is an equal opportunity employer: handicapped individuals are strongly encouraged to apply. The Center for Systems Biology, the MPI-CBG and the MPI-PKS aim to increase the number of women in scientific positions. Female candidates are therefore particularly welcome.

    BACKGROUND

    The School of Computing, Clemson University is seeking a highly motivated research assistant professor in the areas of bioinformatics. The responsibility of research assistant professor will be analyzing transcriptome and re-sequencing data of citrus plants to understand the HLB tolerance/resistance mechanism in citrus.

    REQUIREMENTS

    The ideal candidate will have a Ph.D. in biology, bioinformatics or statistics; proven experiences in analyze next-generation sequencing data is required; proven experiences with citrus is preferred; ability to effectively working individually and as part of a team; proficiency in programming using languages as R. Good communication and writing skill in English is a plus.

    TERMS

    Up to 5-year contract depending upon performance.

    COMPENSATION

    Competitive salary commensurate with the applicant's level of experience.

    HOW TO APPLY

    Applicants should submit a CV, statement of research accomplishments and career goals, and the names, email addresses, and telephone numbers of three references to: Dr. Feng Luo: luofeng[at]clemson.edu

    DEADLINE

    February 1st 2017

    POLICY

    Clemson University is an Equal Opportunity/Affirmative Action/Equal Access Employer.

    BACKGROUND

    The Great Lakes Bioenergy Research Center (GLBRC) is one of three Department of Energy centers established to conduct fundamental, genomics-based research on microbial and plant systems required to realize the national need for low-cost biofuels. The GLBRC is housed at the University of Wisconsin with collaborators at Michigan State University and other universities and national labs.

    As a member of a research team of faculty, staff, post docs, and graduate students, you will help organize, annotate and publish large, complex data sets from a wide variety of research disciplines. The focus of this position is to help develop and maintain a data catalog and a data warehouse of various research data generated at GLBRC. You will also help submit datasets to public data repositories such as NCBI and DOE Systems Biology Knowledge Base. In addition to data, you will also help publish novel scientific software developed at GLBRC. In helping manage this research/scientific data, you will have heavy interfacing with end-users who are Researchers, Scientists, or Software Developers.

    This position requires the ability to work both in a team and independently and the ability to communicate and collaborate with members of an interdisciplinary team. Willingness and ability to rapidly learn new skills, concepts, and technologies is essential. This position offers an opportunity to play an important role in creating a keystone research center for the first great national challenge of the 21st century, sustainable energy independence. For additional information regarding the GLBRC, visit our website: www.glbrc.org.

    REQUIREMENTS

    B.S. or higher in a STEM discipline.

    Demonstrated basic skills and 1-2 years of experience in scientific data handling and data processing script writing plus some knowledge of molecular biology; Being comfortable with using and learning new technologies (e.g., database technology, R scripting, XML editing); Although some training in these technologies will be provided, willingness to find solutions and do trouble shooting independently through searching the web is also needed. Demonstrated capacity to learn quickly, work independently, as well as work well within teams; Attention to detail and the skills to communicate effectively with scientists, software developers, IT and technical staff in person and in writing are extremely important.

    Required Skills:
    • Scripting programming (Perl/Python/R) experience to parse, manipulate and transform datasets from various file formats.
    • Working knowledge of Linux/Unix environment
    • Excellent verbal and written communication skills
    • Understanding of NGS and other "omics" technologies and datatypes
    • Multi-tasking and comfortable in working in a fast-paced environment
    Additional Helpful Skills:
    • NGS Data Analysis skills
    • Database development (relational and noSQL)
    • Software design, development and testing
    • Web-based development understanding
    • Technical writing experience
    • Familiarity with public repositories of high-throughput biological data, such as various databases maintained by NCBI, EBI etc.

    TERMS

    This is a renewable 100% appointment.

    Anticipated begin date: FEBRUARY 07, 2017

    LOCALE

    Wisconsin Energy Institute
    1552 University Ave
    Madison, WI 53726-4084

    COMPENSATION

    $50,000 - $70,000 ANNUAL (12 months), depending on qualifications

    HOW TO APPLY

    In order to apply, applications must be submitted online at: jobs.hr.wisc.edu/cw/e[...]alyst

    In order to be considered for this position, please upload your resume, cover letter and references by the deadline.

    Applications received by the deadline will receive full consideration. Applicants will be asked to upload a resume, cover letter, and contact information for three professional references.

    Questions about the position can be directed to:
    Emily Hickey
    3146 Wisconsin Energy Institute
    Email: ehickey2[at]wisc.edu
    Phone: 608-890-2286

    Relay Access (WTRS): 7-1-1 (out-of-state: TTY: 800.947.3529, STS: 800.833.7637) and above Phone number (See RELAY_SERVICE for further information. )

    DEADLINE

    TO ENSURE CONSIDERATION: Application must be received by FEBRUARY 02, 2017

    POLICY

    A criminal background check will be conducted prior to hiring.

    A period of evaluation will be required.

    If you need to request an accommodation because of a disability you can find information about how to make a request at the following website: www.oed.wisc.edu/478.htm

    Please indicate in writing if you request that your identity be kept confidential. If you do not indicate your preference to remain confidential, the University may be required to disclose your identify and/or application materials. The identity of finalists and successful candidates will be revealed upon request. See Wis. Stat. sec. 19.36(7).

    UW-Madison is an equal opportunity/affirmative action employer.

    We promote excellence through diversity and encourage all qualified individuals to apply.

    BACKGROUND

    A 3 year postdoctoral position is available within Professor Caroline Dive's Clinical and Experimental Pharmacology Group to conduct cutting edge translational research on Small Cell Lung Cancer (SCLC). The focus of our research is translational medicine with an emphasis on next-generation sequencing in the characterisation of tumour heterogeneity, as well as prognostic or predictive biomarker discovery to aid novel therapeutics and clinical efficacy.

    RESPONSIBILITIES

    The successful candidate will focus on unique lung cancer circulating tumour cell (CTC) derived explant tumour models (CDX) and analysis of CTCs isolated from lung cancer patients (see Hodgkinson et al., Nature Medicine, 2014). As an integral part of multidisciplinary teams investigating the biology of lung cancer there will be a particular focus on defining mechanisms of chemoresistance to standard of care therapy, as well as identifying predictive biomarkers for novel therapeutics. We have developed a library of CDX representing the full spectrum of chemosensitivity found in SCLC patients. These CDX have been used to generate an integrated oncogenomic dataset with the intent of developing novel platforms to investigate tumour response to both standard-of-care and novel targeted agents.

    REQUIREMENTS

    The successful applicant should have a PhD in computational biology, mathematics, computer science or a related discipline.

    PREFERENCES

    A background in cancer biology is desirable but not required.

    TERMS

    The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. We are adjacent to The Christie NHS Foundation Trust (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

    Our aim is to understand the fundamental basis of cancer and apply that knowledge to developing new treatment strategies for cancer patients. Our advanced research programmes span a spectrum of cancer research, from the molecular and cellular basis of cancer through to drug discovery, translational research and clinical trials.

    The Institute has outstanding laboratory facilities and exceptional core services, including next generation sequencing, microarrays, confocal microscopy, bioinformatics, histology and mass-spectrometry.

    LOCALE

    We are situated in Manchester, England, a vibrant and dynamic city that is surrounded by beautiful countryside and has excellent transport links both nationally and internationally.

    COMPENSATION

    • Salary in the range of £30,000 - £39,800 (dependent upon qualifications and experience)
    • Job Ref: MI/15/80-4
    • Duration of post: 3 years

    HOW TO APPLY

    Informal enquiries should be directed to Professor Caroline Dive, email: caroline.dive[at]cruk.manchester.ac.uk or her Preclinical Pharmacology Team lead Dr Kris Frese, email: kris.frese[at]cruk.manchester.ac.uk

    To apply for this position please visit our website: www.cruk.manchester.ac.uk

    For applicants who are unable to download this information from our website, please contact HR department on 0161 446 3231, email: jobs[at]cruk.manchester.ac.uk to have this information sent by post.

    DEADLINE

    Closing date: 5 February 2017

    BACKGROUND

    The Center for Infection and Immunity in the Mailman School of Public Health at Columbia University - one of the world's most advanced academic centers focused on microbial surveillance, discovery and diagnosis has an immediate opening for Sr. Programmer Analyst in Bioinformatics for developing pipelines to analyze large-scale gene expression datasets. The successful applicant will join a dynamic laboratory consisting of approximately 50 personnel at Columbia University and a global network of researchers that work on projects related to infectious disease surveillance and discovery in humans and wildlife, host response to infections, microbiome research and large-scale studies on autism and chronic fatigue syndrome/myalgic encephalomyelitis.

    DUTIES & RESPONSIBILITIES

    • Provide bioinformatic support for projects related to microbial detection and discovery – 40%
    • Provide bioinformatics support for RNA-Seq analysis, transcriptomics in a large and dynamic laboratory – 40%
    • Manage databases – 10%
    • Contribute to publications and research grants – 5%
    • Perform other related duties as assigned – 5%

    REQUIREMENTS

    The candidate is expected to demonstrate the following skills and experience:
    • Advanced knowledge of bioinformatics, statistics, systems biology, including biological pathway and network analysis, with working knowledge of writing pipelines for analysis of gene expression data from Illumina sequencing platform
    • Thorough knowledge of NGS experimental design, data quality control, mapping software such as Bowtie, BWA or STAR, normalization and clustering methods, Tuxedo Suite tools such as Tophat and Cufflinks, Gene Set Enrichment Analysis, Ingenuity Pathway analysis and UCSC genome browser
    • Experience with genome annotations from major bioinformatics resources (NCBI, UCSC)
    • Ability to work in Unix environments consisting of high performance clusters
    • Advanced understanding of multi-threading tools (SGE, MPI), resource management and allocation
    • Broad knowledge scripting languages, such as Shell, Python, Perl and R in an academic or industrial environment. Proficiency in R and Bioconductor packages is desirable.
    Minimum Qualifications:
    • Requires a bachelor's degree in bioinformatics or computer science and at least four years of experience in bioinformatics.
    Preferred Qualifications:
    • Master's degree with 2 years of related experience
    The individual should be highly motivated and enjoy work in a fast paced environment.

    COMPENSATION

    Salary will be competitive and commensurate with experience. Columbia University offers a comprehensive and attractive benefits package (Benefits Highlights for Officers 2015 – hr.columbia.edu/benefits/bib)

    HOW TO APPLY

    Please visit jobs.columbia.edu/appl[...]59512

    BACKGROUND

    A POSTDOCTORAL FELLOW position is currently open in Dr. Claire Fraser's laboratory at the Institute for Genome Sciences (IGS). The IGS at the University of Maryland, School of Medicine (UMSOM) is an interdisciplinary, multi-departmental team of collaborative investigators with a broad research program related to the genomics of infectious disease agents, human microbial metagenomics, human genomics, and bioinformatics. The impact of the members of IGS on the field of genomics has been substantial, with more than 500 publications during the past 15 years that have been cited more than 30,000 times.

    The successful candidate will benefit from a community of interactive research labs, bioinformatics programmers, and a variety of sequencing, and computational resources available at the Institute for Genome Sciences as well as a wide range of basic and translational research within the University of Maryland, School of Medicine.

    RESPONSIBILITIES

    We are looking for a post-doctoral fellow to participate in a project to study the impact of exposure to HIV at birth on the gut microbiota in a cohort of infants from Nigeria. In sub-Saharan Africa, the scale-up of antiretroviral (ARV) prophylaxis for the prevention of mother-to-child HIV transmission has dramatically reduced the number of infants becoming infected, with a resulting increase n the number of HIV-exposed, uninfected (HIV-EU) children being born. Under appreciated is a growing body of data that these HIV- EU are at risk for early life development abnormalities including growth faltering, higher morbidities, and increased risk for infant diarrhea during the first two years of life compared to children born to HIV-uninfected mothers (HIV-unexposed, HIV-UU). The post-doctoral fellow on this project will characterize the structure and function of the gut microbiota in HIV-EU and HIV-UU infants and determine the associations between clinical outcomes and microbiota.

    REQUIREMENTS

    We are looking for highly motivated candidates with a PhD in the life sciences, demonstrated experience in genomics or bioinformatics, excellent communication skills, both oral and written, and enthusiasm for scientific collaborations.

    LOCALE

    The University of Maryland School of Medicine, Baltimore, MD

    HOW TO APPLY

    To apply, please send a CV, detailing your list of publications, a cover letter describing your experience and statement of research interests (1-2 pages), and contact information for two references to IGS-jobs[at]som.umaryland.edu

    DEADLINE

    Consideration of candidates will begin upon receipt of applications and will be accepted through April 15, 2017. Anticipated start date for the positions is summer 2017.

    POLICY

    AA/EOE/ADA

    BACKGROUND

    The Duke Human Vaccine Institute and the Duke Center for HIV/AIDS Vaccine Immunology & Immunogen Discovery (CHAVI-ID), providing national and international leadership in the fight against major infectious diseases such as HIV, influenza, and malaria, are currently recruiting for a highly motivated individual to join our team. The Duke Human Vaccine Institute (DHVI) is an interdisciplinary, interdepartmental institute dedicated to the study of basic and translational science required to understand host-pathogen interactions that can be translated to vaccines against human diseases. DHVI comprises a team of highly interactive investigators that have expertise in mucosal and systemic virology, immunology, molecular biology, microbiology and animal models.

    RESPONSIBILITIES

    The Bioinformatician will provide specialized bioinformatics solutions, develop and implement innovative computational approaches for the analysis of large sequence datasets generated by next generation sequencing platforms as well as design, implement and test a high-performance computing pipeline for analyzing large-scale transcriptomics. In addition, this position will assist in the structural modeling and analysis of antibody-antigen interactions, implement computational protein design algorithms for improving vaccine immunogen designs, and assist in the creation of a software pipeline and database system for analyzing and cataloging antibody sequences.

    REQUIREMENTS

    The position requires a Master's degree in bioinformatics, computer science, computational biology, or a related field. A PhD is a plus. A minimum of five years relevant experience is required including experience in a UNIX/Linux environment, the development of computational methods and programs for the analysis of genomic and/or structural data, web-based bioinformatics tools, public domain biological databases and software tools for sequence and structural analysis. Experience with Perl or Python, R or MATLAB, web design, database systems, high performance computing environments, and statistics is also desired. Proficiency in C++ programming is highly preferred.

    HOW TO APPLY

    Candidates should apply to requisition 401207985 on the Duke employment website and send a cover letter and current CV to:

    Duke Human Vaccine Institute
    Email: dhvicareers[at]dm.duke.edu
    (Please reference "BIO-KW" in subject line of email)

    POLICY

    Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's race, color, religion, age, sex, gender identity, gender expression, sexual orientation, national origin, genetic information, veteran status, or disability.

    DESCRIPTION

    We are looking for one PhD student to join a bioinformatics group based at the Faculty of Health Sciences, University of Manitoba and Data Science Platform of George and Fay Yee Centre for Healthcare Innovation. The candidate should have a thesis-based Master's degree and has good programming skill using R. The candidate should have a GPA >3.5.

    Applicants who have been trained in life science (such as cancer biology, genetics, bioinformatics) will register in graduate program in the Department of Biochemistry and Medical Genetics. This position can start in May or September, 2017.

    Applicants who have been trained in computer science will register in graduate program in the Department of Computer Science (www.cs.umanitoba.ca/graduate/) or Department of Electrical and Computer Engineering. This position can start in September 2017.

    HOW TO APPLY

    Applicants should send their CV, transcripts and English test results to Dr. Pingzhao Hu at pingzhao.hu[at]umanitoba.ca.

    For more information: www.hu-bioinformaticslab.org

    BACKGROUND

    The Translational Genomics Research Institute (TGen) is a preeminent leader in precision medicine, translating genetic and genomic discoveries with life changing results. We are defining 21st century health care delivery with major advances in genomic-enabled medicine that are revolutionizing how to prevent, diagnose and treat diseases. TGen specializes in helping patients with cancer, neurodegenerative disorders, infectious disease, metabolic diseases, and rare childhood disease. Our translational research enterprise provides an unparalleled environment for innovation, discovery and creative collaboration supported by physicians and scientists who are prominent leaders in their fields. For more information, visit: www.tgen.org.

    RESPONSIBILITIES

    The primary job responsibility of the selected candidate will be the management of the main analysis pipeline used at TGen to automate the analysis of next-generation sequencing data. This job will involve frequent interactions with project leaders around the institute to develop project specific processes and to ensure projects are analyzed in timely manner. The successful candidate can expect to be exposed to a diverse array of diseases and will be a key member of our analytical team working to improve the health and outcomes for our patients.

    Duties and Responsibilities:
    • The associate bioinformatician will process biomedical data by utilizing/applying existing informatics/software resources/analysis methods on multiple computing platforms/in multiple programming languages, automating/managing repetitive tasks, developing small-scale software modules, assist in extracting/ organizing/ manipulating/ annotating/ visualizing/ summarizing data from diverse data sources to aid knowledge discovery and inference process, and carry out custom bioinformatics tasks as required and specified by the senior staff and supervisors.
    • Implementation, application, maintenance, customization of available/known informatics resources and scientific software/data sources in multiple programming languages/platforms for research support. Developing front-ends for other analysis tools, visualization/compilation of results, facilitating generally defined routine data processing/migration/organization/management tasks, and building project specific workflows implementing automated analysis steps.
    • Investigation, customization, prototyping for new bioinformatics resources and scientific software for biomedical data processing. Requires skills in multiple programming languages, databases, computational methods, scientific computing, large scale data analysis, and heterogeneous biomedical data from multiple sources. Using software engineering skills towards creating reusable, modular, tested, version-controlled, shared repository oriented, professional quality informatics/software/database resources.
    • Designing, prototyping, evaluating innovative computational algorithms, data analysis, and statistical methods for biomedical data processing, interpretation and knowledge mining of data, computational algorithms, databases, scientific computing, large-scale data analysis. Suggesting/exploring alternative/multiple data processing approaches.
    • Following scientific literature/manuscripts, investigating new biomedical data processing methods, trends, technologies, and paradigms relevant to biomedical informatics, providing feedback towards scientific findings and contributing towards manuscripts/grants/research proposals and research planning. Attending/contributing to/presenting at internal/external scientific meetings/conferences
    • Managing multiple bioinformatics collaborations/projects, mentoring junior staff. Strategic planning, organization, management, organization, utilization, optimization of existing and future bioinformatics resources, skills, and needs. Interacting with PIs, researchers and other bioinformaticians towards aligning/guiding the bioinformatics activities to maximize organization's competitive advantage in biomedical research. Interacting with other research divisions, computing infrastructure staff, outside academic/industrial partners.

    REQUIREMENTS

    • Bachelor's Degree and less than 6 months job-related experience
    • Bachelors/Master's Degree in Bioinformatics/Computer Science/Bioengineering/Computational Biology or related field

    HOW TO APPLY

    If you are interested in seeing the most up to date job listings or to apply for this position, please go to www.tgen.org/home[...]bru70 and submit your resume. Please take a moment to read about our employee benefits and learn more about TGen. If you have any questions about the company or how to apply for a position, please contact hr[at]tgen.org.

    Only resumes submitted through the TGen career website will be considered.

    POLICY

    We value and support diversity in our workforce.
    EEO/AA

    BACKGROUND

    The Strawberry Molecular Genetics and Genomics Laboratory at the Gulf Coast Research and Education Center (GCREC), Institute of Food and Agricultural Sciences, University of Florida, is seeking a highly motivated postdoctoral research associate to conduct genomics and bioinformatics research. This position will provide ample opportunity for the motivated scientist to conduct productive research and publish high quality manuscripts.

    The University of Florida (www.ufl.edu) is a Land-Grant and Sea-Grant institution, encompassing virtually all academic and professional disciplines, with an enrollment of more than 60,000 students. The Institute of Food and Agricultural Sciences (ifas.ufl.edu) includes the College of Agricultural and Life Sciences (cals.ufl.edu), the Florida Agricultural Experiment Station (research.ifas.ufl.edu), the Florida Cooperative Extension Service (extension.ifas.ufl.edu), the College of Veterinary Medicine (www.vetmed.ufl.edu), the Florida Sea Grant program (www.flseagrant.org ), and encompasses 17 on-campus academic departments and schools, 13 Research and Educational Centers (REC) located throughout the state, 6 Research sites/demonstration units administered by RECs or academic departments, and Florida Cooperative Extension Service offices in all 67 counties (counties operate and maintain).

    The GCREC is home to 19 UF faculty and has been rated as one of the top workplaces in the Tampa Bay Area. The research center is located 25 minutes from downtown Tampa and 2 hours from the UF main campus in Gainesville, FL.

    RESPONSIBILITIES

    The successful candidate will participate in processing and analyzing next generation sequencing data to characterize the complex genome structure of octoploid strawberry. This large genomic data set will be applied for the discovery of genes associated with fruit quality, flavor, and disease resistance. Also, the appointee is expected to work closely with other researchers and students in the strawberry breeding program and assist in the analysis of sequence data for several ongoing projects.

    REQUIREMENTS

    • PhD degree in Biology, Bioinformatics, Computational Biology, Genomics, or related life sciences discipline
    • Ability to develop new bioinformatics tools for the strawberry molecular breeding program
    • Ability to work closely and harmoniously with the team of scientists in the strawberry genomics and breeding programs
    • Excellent communication and writing skills, independent problem solving, self-learning abilities, self-motivation and creativity
    • Excellent academic record

    PREFERENCES

    • At least 2 years of experience providing bioinformatics supports to scientists, or postdoctoral experience in bioinformatics/genomics
    • Working or collaborative experience in plant breeding programs
    • Programming skills with Java, C/C++, or Perl and efficiency in Linux/Unix operating systems
    • Ability to develop web-based support tool for genomics-assisted breeding
    • Proficiency in analyzing large-scale sequence data and complex genome assembly
    • Experience in RNAseq, RenSeq, target region capture sequencing, Fosmid/BAC library construction and sequencing

    TERMS

    The position is available immediately, and initial appointment is for two years. A renewal of the appointment will be contingent based on success of research program (individual performance and publications) and funding availability.

    COMPENSATION

    The minimum salary is $47,500, commensurate with experience.

    See postdoc.aa.ufl.edu

    HOW TO APPLY

    Interested candidates for this position are encouraged to send a cover letter (maximum 3 pages with statement of research interest), curriculum vita, and contact information for three references to Dr. Seonghee Lee (seonghee105[at]ufl.edu).

    DEADLINE

    1/31/2017

    BACKGROUND

    We are looking for a Software Developer (or Senior Software Developer depending on experience) to work in Dr. Gosia Trynka's team at the Wellcome Trust Sanger Institute. Our group is an interactive mix of experimental and computational researchers. We combine immunology and genomic assays to understand the role of genetic variants in predisposing to development of immune diseases. We use computational and statistical methods to analyze large genomic datasets to better understand the causes of a wide range of human disorders, including celiac disease, rheumatoid arthritis, type 1 diabetes and inflammatory bowel disease.

    This multifaceted role involves software development on open-source applications built for analysis of genomic data, scripting and analysis of big datasets, and design and implementation of the team's databases and software repositories. The successful candidate will be part of scientific analyses and discussions within the team, and will be expected to generate ideas for computational solutions to research problems. An interest in scientific research and a strong intellectual curiosity are necessities, whereas formal education in biology or genetics is helpful but not required. Highly skilled developers are encouraged to apply regardless of prior job experience, as the focus is on coding and core computer science skills rather than on work experience. Recent graduates or current students in their final year are also encouraged to apply, although it is essential that any candidate has substantial development experience outside of coursework (e.g. active participation in open source projects or the pursuit of personal coding projects).

    The successful applicant will have access to Sanger's world-class computational resources, including a 10,000+ core computational cluster and multiple petabytes of high-speed cluster filesystems (including over two petabytes of storage dedicated for human genetics use). Our work is also supported by an extremely knowledgeable and proactive systems group that maintains the core hardware and software infrastructure. The Sanger shares the Genome Campus with the European Bioinformatics Institute (EBI), and hosts a weekly talks on a variety of topics including informatics, given both by internal and external invited speakers. You would also have the opportunity to occasionally attend courses and/or conferences in order to keep up to date with new practices relevant to our work, both locally and potentially internationally.

    REQUIREMENTS

    Essential Skills:
    • BSc/BA in a computational or quantitative science discipline
    • Strong background in computer programming, with experience in both large scale project development and smaller scripting tasks (e.g. via awk/perl/python)
    • Knowledge of core development concepts (e.g. object oriented design, version control)
    • Experience in UNIX computing environments
    • Capacity for self-organization, timeline estimation, and teamwork

    PREFERENCES

    Ideal Skills:
    • MSc/MPhil/PhD in a computational or quantitative science discipline
    • Knowledge of computer science concepts (e.g. machine learning, hidden markov models)
    • Experience using high performance compute farms
    • Interest or experience in human disease genetics or medical genomics
    • Experience with large scale (terabytes or more) data processing

    COMPENSATION

    Salary range £31498 to £39729 pa plus excellent benefits. (Senior Software Developer). Salary range £24589 to £30995 pa plus excellent benefits. (Software Developer).

    Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

    ABOUT US

    The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited's 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society. To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

    HOW TO APPLY

    Please submit a cover letter and CV with your application. Application Link: jobs.sanger.ac.uk/wd/p[...]97085

    DEADLINE

    The closing date for applications is 20th January 2017.

    POLICY

    Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.
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