Basic Information
Gene ID 107823 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Whsc1; Kiaa1090, Nsd2
Full Name Histone-lysine N-methyltransferase NSD2
Organism Mus musculus [10090]

Cross Reference
UniProt Q8BVE8 UniGene Mm.491382
PDB NULL OMIM NULL
KEGG mmu:107823 UCSC uc012duw.1

Protein Interactions
DIP DIP-60452N
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000067205 Gene3D G3DSA:1.10.30.10 IPR009071 459 505 2.50e-09 High mobility group box domain
ENSMUSP00000067205 Gene3D G3DSA:3.30.40.10 IPR013083 1213 1288 6.30e-11 Zinc finger, RING/FYVE/PHD-type
ENSMUSP00000067205 Gene3D G3DSA:3.30.40.10 IPR013083 654 713 3.40e-11 Zinc finger, RING/FYVE/PHD-type
ENSMUSP00000067205 Gene3D G3DSA:3.30.40.10 IPR013083 819 877 2.00e-14 Zinc finger, RING/FYVE/PHD-type
ENSMUSP00000067205 Pfam PF00505 IPR009071 459 506 3.90e-10 High mobility group box domain
ENSMUSP00000067205 Pfam PF00628 IPR019787 834 875 1.40e-07 Zinc finger, PHD-finger
ENSMUSP00000067205 Pfam PF00855 IPR000313 220 326 4.70e-23 PWWP domain
ENSMUSP00000067205 Pfam PF00855 IPR000313 881 968 4.40e-17 PWWP domain
ENSMUSP00000067205 Pfam PF00856 IPR001214 1075 1181 1.30e-25 SET domain
ENSMUSP00000067205 ProSitePatterns PS01359 IPR019786 671 711 - Zinc finger, PHD-type, conserved site
ENSMUSP00000067205 ProSitePatterns PS01359 IPR019786 835 873 - Zinc finger, PHD-type, conserved site
ENSMUSP00000067205 ProSiteProfiles PS50016 IPR019787 668 714 0.00e-00 Zinc finger, PHD-finger
ENSMUSP00000067205 ProSiteProfiles PS50016 IPR019787 832 876 0.00e-00 Zinc finger, PHD-finger
ENSMUSP00000067205 ProSiteProfiles PS50089 IPR001841 718 764 0.00e-00 Zinc finger, RING-type
ENSMUSP00000067205 ProSiteProfiles PS50118 IPR009071 453 502 0.00e-00 High mobility group box domain
ENSMUSP00000067205 ProSiteProfiles PS50280 IPR001214 1064 1181 0.00e-00 SET domain
ENSMUSP00000067205 ProSiteProfiles PS50812 IPR000313 222 286 0.00e-00 PWWP domain
ENSMUSP00000067205 ProSiteProfiles PS50812 IPR000313 881 943 0.00e-00 PWWP domain
ENSMUSP00000067205 ProSiteProfiles PS50868 IPR003616 1188 1204 0.00e-00 Post-SET domain
ENSMUSP00000067205 ProSiteProfiles PS51215 IPR006560 1012 1062 0.00e-00 AWS
ENSMUSP00000067205 SMART SM00184 IPR001841 671 711 5.70e-02 Zinc finger, RING-type
ENSMUSP00000067205 SMART SM00184 IPR001841 718 763 2.00e-04 Zinc finger, RING-type
ENSMUSP00000067205 SMART SM00249 IPR001965 1242 1285 1.00e-10 Zinc finger, PHD-type
ENSMUSP00000067205 SMART SM00249 IPR001965 670 712 6.70e-09 Zinc finger, PHD-type
ENSMUSP00000067205 SMART SM00249 IPR001965 717 764 3.50e-03 Zinc finger, PHD-type
ENSMUSP00000067205 SMART SM00249 IPR001965 834 874 1.20e-12 Zinc finger, PHD-type
ENSMUSP00000067205 SMART SM00293 IPR000313 220 285 2.00e-17 PWWP domain
ENSMUSP00000067205 SMART SM00293 IPR000313 879 941 1.30e-25 PWWP domain
ENSMUSP00000067205 SMART SM00317 IPR001214 1064 1187 2.20e-45 SET domain
ENSMUSP00000067205 SMART SM00398 IPR009071 452 522 2.60e-11 High mobility group box domain
ENSMUSP00000067205 SMART SM00508 IPR003616 1188 1204 3.00e-06 Post-SET domain
ENSMUSP00000067205 SMART SM00570 IPR006560 1012 1063 9.90e-30 AWS
ENSMUSP00000067205 SUPERFAMILY SSF47095 IPR009071 444 506 0.00e-00 High mobility group box domain
ENSMUSP00000067205 SUPERFAMILY SSF57903 IPR011011 1217 1285 0.00e-00 Zinc finger, FYVE/PHD-type
ENSMUSP00000067205 SUPERFAMILY SSF57903 IPR011011 663 712 0.00e-00 Zinc finger, FYVE/PHD-type
ENSMUSP00000067205 SUPERFAMILY SSF57903 IPR011011 822 888 0.00e-00 Zinc finger, FYVE/PHD-type

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000067205 PF00855 2.29953e-42 PWWP PWWP domain
ENSMUSP00000067205 PF00856 1.3e-25 SET SET domain
ENSMUSP00000067205 PF00628 1e-15 PHD PHD-finger
ENSMUSP00000067205 PF00505 1.4e-10 HMG_box HMG (high mobility group) box
ENSMUSP00000067205 PF09011 0.0002 HMG_box_2 HMG-box domain

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
30195 Bombus terrestris 100649537 9597 Pan paniscus 100993332
39432 Saimiri boliviensis 101052056 7425 Nasonia vitripennis 100116149
132113 Bombus impatiens 100743680 9595 Gorilla gorilla 101140725
9669 Mustela putorius furo 101690532 9606 Homo sapiens 7468
28377 Anolis carolinensis ENSACAG00000007905 9646 Ailuropoda melanoleuca ENSAMEG00000014221
9913 Bos taurus ENSBTAG00000007986 9483 Callithrix jacchus ENSCJAG00000001876
10141 Cavia porcellus ENSCPOG00000007513 10020 Dipodomys ordii ENSDORG00000013095
9365 Erinaceus europaeus ENSEEUG00000014911 9685 Felis catus ENSFCAG00000010620
9785 Loxodonta africana ENSLAFG00000008162 9315 Macropus eugenii ENSMEUG00000009817
9103 Meleagris gallopavo ENSMGAG00000013051 9544 Macaca mulatta ENSMMUG00000009943
13616 Monodelphis domestica ENSMODG00000004162 61853 Nomascus leucogenys ENSNLEG00000000081
30611 Otolemur garnettii ENSOGAG00000014890 9813 Procavia capensis ENSPCAG00000006545
7757 Petromyzon marinus ENSPMAG00000003901 9601 Pongo abelii ENSPPYG00000014534
9823 Sus scrofa ENSSSCG00000008682 9739 Tursiops truncatus ENSTTRG00000013701
7668 Strongylocentrotus purpuratus 580047 9615 Canis familiaris ENSCAFG00000014951
9358 Choloepus hoffmanni ENSCHOG00000005628 9361 Dasypus novemcinctus ENSDNOG00000010075
9371 Echinops telfairi ENSETEG00000003950 7897 Latimeria chalumnae ENSLACG00000010693
9258 Ornithorhynchus anatinus ENSOANG00000014321 9986 Oryctolagus cuniculus ENSOCUG00000005245
9978 Ochotona princeps ENSOPRG00000002707 13735 Pelodiscus sinensis ENSPSIG00000006591
132908 Pteropus vampyrus ENSPVAG00000000845 42254 Sorex araneus ENSSARG00000001096
9305 Sarcophilus harrisii ENSSHAG00000006750 43179 Ictidomys tridecemlineatus ENSSTOG00000003369
37347 Tupaia belangeri ENSTBEG00000013959 59729 Taeniopygia guttata ENSTGUG00000010558
8364 Xenopus tropicalis ENSXETG00000026376