Basic Information
Gene ID 11906 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Zfhx3
Full Name Zinc finger homeobox protein 3
Organism Mus musculus [10090]

Cross Reference
UniProt E9QMD3 UniGene Mm.477670
PDB NULL OMIM NULL
KEGG mmu:11906 UCSC uc009nid.1

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000044612 Gene3D G3DSA:1.10.10.60 IPR009057 2149 2202 3.70e-17 Homeodomain-like
ENSMUSP00000044612 Gene3D G3DSA:1.10.10.60 IPR009057 2235 2301 4.30e-19 Homeodomain-like
ENSMUSP00000044612 Gene3D G3DSA:1.10.10.60 IPR009057 2630 2707 2.10e-18 Homeodomain-like
ENSMUSP00000044612 Gene3D G3DSA:1.10.10.60 IPR009057 2938 3006 9.90e-21 Homeodomain-like
ENSMUSP00000044612 Gene3D G3DSA:3.30.160.60 IPR013087 1604 1626 1.60e-06 Zinc finger C2H2-type/integrase DNA-binding domain
ENSMUSP00000044612 Gene3D G3DSA:3.30.160.60 IPR013087 725 753 1.00e-05 Zinc finger C2H2-type/integrase DNA-binding domain
ENSMUSP00000044612 Pfam PF00046 IPR001356 2153 2209 4.60e-13 Homeobox domain
ENSMUSP00000044612 Pfam PF00046 IPR001356 2250 2306 4.70e-17 Homeobox domain
ENSMUSP00000044612 Pfam PF00046 IPR001356 2651 2707 7.00e-17 Homeobox domain
ENSMUSP00000044612 Pfam PF00046 IPR001356 2955 3011 2.60e-15 Homeobox domain
ENSMUSP00000044612 Pfam PF00096 IPR007087 1606 1630 1.20e-02 Zinc finger, C2H2
ENSMUSP00000044612 Pfam PF00096 IPR007087 673 695 1.60e-02 Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00027 IPR017970 2185 2208 - Homeobox, conserved site
ENSMUSP00000044612 ProSitePatterns PS00027 IPR017970 2683 2706 - Homeobox, conserved site
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 1264 1285 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 1372 1395 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 1413 1433 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 1441 1462 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 1557 1579 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 1608 1630 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 1992 2013 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 2541 2561 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 2722 2743 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 284 305 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 3034 3056 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 3551 3573 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 643 664 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 674 695 - Zinc finger, C2H2
ENSMUSP00000044612 ProSitePatterns PS00028 IPR007087 81 103 - Zinc finger, C2H2
ENSMUSP00000044612 ProSiteProfiles PS50071 IPR001356 2150 2210 0.00e-00 Homeobox domain
ENSMUSP00000044612 ProSiteProfiles PS50071 IPR001356 2247 2307 0.00e-00 Homeobox domain
ENSMUSP00000044612 ProSiteProfiles PS50071 IPR001356 2648 2708 0.00e-00 Homeobox domain
ENSMUSP00000044612 ProSiteProfiles PS50071 IPR001356 2952 3012 0.00e-00 Homeobox domain
ENSMUSP00000044612 ProSiteProfiles PS50157 IPR007087 1370 1400 0.00e-00 Zinc finger, C2H2
ENSMUSP00000044612 ProSiteProfiles PS50157 IPR007087 1411 1433 0.00e-00 Zinc finger, C2H2
ENSMUSP00000044612 ProSiteProfiles PS50157 IPR007087 1555 1586 0.00e-00 Zinc finger, C2H2
ENSMUSP00000044612 ProSiteProfiles PS50157 IPR007087 1606 1635 0.00e-00 Zinc finger, C2H2
ENSMUSP00000044612 ProSiteProfiles PS50157 IPR007087 1990 2018 0.00e-00 Zinc finger, C2H2
ENSMUSP00000044612 ProSiteProfiles PS50157 IPR007087 2335 2364 0.00e-00 Zinc finger, C2H2
ENSMUSP00000044612 ProSiteProfiles PS50157 IPR007087 2539 2561 0.00e-00 Zinc finger, C2H2
ENSMUSP00000044612 ProSiteProfiles PS50157 IPR007087 2720 2750 0.00e-00 Zinc finger, C2H2
ENSMUSP00000044612 ProSiteProfiles PS50157 IPR007087 727 756 0.00e-00 Zinc finger, C2H2
ENSMUSP00000044612 SMART SM00355 IPR015880 1041 1065 1.30e-02 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 1089 1113 4.60e-04 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 1233 1256 1.40e-04 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 1262 1285 1.50e-03 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 1370 1395 3.50e-04 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 1411 1433 1.20e-04 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 1439 1462 2.70e-03 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 1555 1579 2.80e-04 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 1606 1630 3.90e-04 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 1990 2013 5.60e-03 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 2335 2355 5.70e-02 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 2539 2561 5.80e-05 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 2720 2743 2.60e-04 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 282 305 4.50e-02 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 3032 3056 2.80e-02 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 3489 3509 4.90e-01 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 3549 3573 5.90e-02 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 641 664 1.20e-02 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 672 695 2.30e-05 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 727 751 1.60e-06 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 79 103 2.60e-02 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 805 829 2.20e-04 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00355 IPR015880 985 1009 1.50e-02 Zinc finger, C2H2-like
ENSMUSP00000044612 SMART SM00389 IPR001356 2152 2214 4.60e-19 Homeobox domain
ENSMUSP00000044612 SMART SM00389 IPR001356 2249 2311 9.90e-23 Homeobox domain
ENSMUSP00000044612 SMART SM00389 IPR001356 2650 2712 1.20e-22 Homeobox domain
ENSMUSP00000044612 SMART SM00389 IPR001356 2954 3016 4.20e-20 Homeobox domain
ENSMUSP00000044612 SMART SM00451 IPR003604 1086 1120 6.40e-03 Zinc finger, U1-type
ENSMUSP00000044612 SMART SM00451 IPR003604 1552 1586 4.80e-03 Zinc finger, U1-type
ENSMUSP00000044612 SMART SM00451 IPR003604 1603 1637 2.00e-02 Zinc finger, U1-type
ENSMUSP00000044612 SMART SM00451 IPR003604 3029 3063 8.30e-04 Zinc finger, U1-type
ENSMUSP00000044612 SMART SM00451 IPR003604 3546 3580 6.40e-03 Zinc finger, U1-type
ENSMUSP00000044612 SMART SM00451 IPR003604 724 758 2.70e-03 Zinc finger, U1-type
ENSMUSP00000044612 SMART SM00451 IPR003604 982 1016 1.10e-02 Zinc finger, U1-type
ENSMUSP00000044612 SUPERFAMILY SSF46689 IPR009057 2151 2223 0.00e-00 Homeodomain-like
ENSMUSP00000044612 SUPERFAMILY SSF46689 IPR009057 2248 2312 0.00e-00 Homeodomain-like
ENSMUSP00000044612 SUPERFAMILY SSF46689 IPR009057 2637 2707 0.00e-00 Homeodomain-like
ENSMUSP00000044612 SUPERFAMILY SSF46689 IPR009057 2943 3011 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000044612 PF00046 0 Homeobox Homeobox domain
ENSMUSP00000044612 PF05920 3.1e-11 Homeobox_KN Homeobox KN domain
ENSMUSP00000044612 PF00096 2e-07 zf-C2H2 Zinc finger, C2H2 type
ENSMUSP00000044612 PF05605 2.9e-05 zf-Di19 Drought induced 19 protein (Di19), zinc-binding
ENSMUSP00000044612 PF12874 3.9e-05 zf-met Zinc-finger of C2H2 type

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000044612 GO:0005634 cellular_component nucleus
ENSMUSP00000044612 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000044612 GO:0008270 molecular_function zinc ion binding
ENSMUSP00000044612 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100116002 132113 Bombus impatiens 100741370
7463 Apis florea 100864500 143995 Megachile rotundata 100877335
9555 Papio anubis 101017132 39432 Saimiri boliviensis 101035646
9796 Equus caballus 100054244 7029 Acyrthosiphon pisum 100161293
30195 Bombus terrestris 100650490 10029 Cricetulus griseus 100759927
9597 Pan paniscus 100973269 9685 Felis catus 101099345
7227 Drosophila melanogaster 43795 9646 Ailuropoda melanoleuca ENSAMEG00000002197
10020 Dipodomys ordii ENSDORG00000016147 9365 Erinaceus europaeus ENSEEUG00000008705
9031 Gallus gallus ENSGALG00000000713 13616 Monodelphis domestica ENSMODG00000002600
9601 Pongo abelii ENSPPYG00000007513 9598 Pan troglodytes ENSPTRG00000008340
132908 Pteropus vampyrus ENSPVAG00000006664 37347 Tupaia belangeri ENSTBEG00000006524
31033 Takifugu rubripes ENSTRUG00000017601 8083 Xiphophorus maculatus ENSXMAG00000011706
9615 Canis familiaris 489729 7668 Strongylocentrotus purpuratus 593587
7070 Tribolium castaneum 657717 9544 Macaca mulatta 706074
28377 Anolis carolinensis ENSACAG00000008238 9358 Choloepus hoffmanni ENSCHOG00000002641
9483 Callithrix jacchus ENSCJAG00000015112 10141 Cavia porcellus ENSCPOG00000009111
51511 Ciona savignyi ENSCSAVG00000009944 7955 Danio rerio ENSDARG00000073944
9371 Echinops telfairi ENSETEG00000014223 69293 Gasterosteus aculeatus ENSGACG00000015779
9595 Gorilla gorilla ENSGGOG00000012083 8049 Gadus morhua ENSGMOG00000002909
7897 Latimeria chalumnae ENSLACG00000015046 9785 Loxodonta africana ENSLAFG00000017476
9315 Macropus eugenii ENSMEUG00000009090 9103 Meleagris gallopavo ENSMGAG00000008764
30608 Microcebus murinus ENSMICG00000003537 59463 Myotis lucifugus ENSMLUG00000016100
9258 Ornithorhynchus anatinus ENSOANG00000005084 9986 Oryctolagus cuniculus ENSOCUG00000017910
30611 Otolemur garnettii ENSOGAG00000010886 8128 Oreochromis niloticus ENSONIG00000014495
9978 Ochotona princeps ENSOPRG00000011379 8090 Oryzias latipes ENSORLG00000007874
9813 Procavia capensis ENSPCAG00000010600 13735 Pelodiscus sinensis ENSPSIG00000004618
10116 Rattus norvegicus ENSRNOG00000014452 42254 Sorex araneus ENSSARG00000011764
9305 Sarcophilus harrisii ENSSHAG00000014394 9823 Sus scrofa ENSSSCG00000002752
43179 Ictidomys tridecemlineatus ENSSTOG00000027206 59729 Taeniopygia guttata ENSTGUG00000008190
9478 Tarsius syrichta ENSTSYG00000000792 9739 Tursiops truncatus ENSTTRG00000002935
8364 Xenopus tropicalis ENSXETG00000023509