Basic Information
Gene ID 593587
Gene Name zfhx4
Full Name PREDICTED: zinc finger homeobox protein 4 isoform 1[Strongylocentrotus purpuratus].
Organism Strongylocentrotus purpuratus [7668]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003723710 Gene3D G3DSA:1.10.10.60 IPR009057 2019 2075 2.50e-15 Homeodomain-like
XP_003723710 Gene3D G3DSA:1.10.10.60 IPR009057 2334 2407 2.80e-18 Homeodomain-like
XP_003723710 Gene3D G3DSA:1.10.10.60 IPR009057 2629 2697 1.90e-19 Homeodomain-like
XP_003723710 Gene3D G3DSA:1.10.10.60 IPR009057 2897 2962 1.60e-17 Homeodomain-like
XP_003723710 Gene3D G3DSA:3.30.160.60 IPR013087 1473 1502 2.70e-05 Zinc finger C2H2-type/integrase DNA-binding domain
XP_003723710 Gene3D G3DSA:3.30.160.60 IPR013087 1523 1550 2.40e-05 Zinc finger C2H2-type/integrase DNA-binding domain
XP_003723710 Gene3D G3DSA:3.30.160.60 IPR013087 649 677 5.00e-06 Zinc finger C2H2-type/integrase DNA-binding domain
XP_003723710 Pfam PF00046 IPR001356 2026 2082 1.60e-11 Homeobox domain
XP_003723710 Pfam PF00046 IPR001356 2351 2407 4.20e-17 Homeobox domain
XP_003723710 Pfam PF00046 IPR001356 2646 2702 5.90e-16 Homeobox domain
XP_003723710 Pfam PF00046 IPR001356 2911 2967 1.40e-14 Homeobox domain
XP_003723710 Pfam PF00096 IPR007087 1323 1345 1.70e-03 Zinc finger, C2H2
XP_003723710 Pfam PF00096 IPR007087 597 619 1.50e-02 Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00027 IPR017970 2058 2081 - Homeobox, conserved site
XP_003723710 ProSitePatterns PS00027 IPR017970 2678 2701 - Homeobox, conserved site
XP_003723710 ProSitePatterns PS00028 IPR007087 1100 1121 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 1131 1152 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 1274 1297 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 1324 1345 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 1431 1453 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 1477 1499 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 1527 1549 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 1830 1851 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 2438 2458 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 2549 2569 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 2716 2737 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 2988 3010 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 299 320 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 567 588 - Zinc finger, C2H2
XP_003723710 ProSitePatterns PS00028 IPR007087 598 619 - Zinc finger, C2H2
XP_003723710 ProSiteProfiles PS50071 IPR001356 2023 2083 0.00e-00 Homeobox domain
XP_003723710 ProSiteProfiles PS50071 IPR001356 2348 2408 0.00e-00 Homeobox domain
XP_003723710 ProSiteProfiles PS50071 IPR001356 2643 2703 0.00e-00 Homeobox domain
XP_003723710 ProSiteProfiles PS50071 IPR001356 2908 2968 0.00e-00 Homeobox domain
XP_003723710 ProSiteProfiles PS50157 IPR007087 1236 1267 0.00e-00 Zinc finger, C2H2
XP_003723710 ProSiteProfiles PS50157 IPR007087 1272 1302 0.00e-00 Zinc finger, C2H2
XP_003723710 ProSiteProfiles PS50157 IPR007087 1322 1350 0.00e-00 Zinc finger, C2H2
XP_003723710 ProSiteProfiles PS50157 IPR007087 1429 1458 0.00e-00 Zinc finger, C2H2
XP_003723710 ProSiteProfiles PS50157 IPR007087 1475 1499 0.00e-00 Zinc finger, C2H2
XP_003723710 ProSiteProfiles PS50157 IPR007087 1525 1554 0.00e-00 Zinc finger, C2H2
XP_003723710 ProSiteProfiles PS50157 IPR007087 1828 1856 0.00e-00 Zinc finger, C2H2
XP_003723710 ProSiteProfiles PS50157 IPR007087 2436 2463 0.00e-00 Zinc finger, C2H2
XP_003723710 ProSiteProfiles PS50157 IPR007087 2547 2569 0.00e-00 Zinc finger, C2H2
XP_003723710 ProSiteProfiles PS50157 IPR007087 2714 2742 0.00e-00 Zinc finger, C2H2
XP_003723710 ProSiteProfiles PS50157 IPR007087 596 624 0.00e-00 Zinc finger, C2H2
XP_003723710 ProSiteProfiles PS50157 IPR007087 651 680 0.00e-00 Zinc finger, C2H2
XP_003723710 SMART SM00355 IPR015880 1098 1121 2.20e-04 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 1129 1152 2.40e-05 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 1236 1256 2.10e-01 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 1272 1297 3.50e-04 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 1322 1345 1.10e-05 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 1429 1453 2.50e-02 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 1475 1499 5.10e-04 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 1525 1549 3.20e-04 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 1718 1738 1.30e-01 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 1828 1851 4.50e-04 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 2436 2458 1.90e-04 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 2547 2569 2.00e-05 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 2714 2737 2.20e-04 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 297 320 6.80e-02 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 2986 3010 7.80e-03 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 3312 3332 3.40e-01 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 3355 3380 9.30e-02 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 565 588 5.30e-03 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 596 619 2.30e-05 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 651 675 7.50e-07 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 710 734 2.70e-04 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 842 863 1.80e-01 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 882 906 2.50e-03 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 938 964 1.50e-01 Zinc finger, C2H2-like
XP_003723710 SMART SM00355 IPR015880 988 1012 3.00e-04 Zinc finger, C2H2-like
XP_003723710 SMART SM00389 IPR001356 2025 2087 3.40e-14 Homeobox domain
XP_003723710 SMART SM00389 IPR001356 2350 2412 2.70e-23 Homeobox domain
XP_003723710 SMART SM00389 IPR001356 2645 2707 1.40e-20 Homeobox domain
XP_003723710 SMART SM00389 IPR001356 2910 2972 1.90e-17 Homeobox domain
XP_003723710 SMART SM00451 IPR003604 1472 1506 2.40e-03 Zinc finger, U1-type
XP_003723710 SMART SM00451 IPR003604 1522 1556 1.30e-03 Zinc finger, U1-type
XP_003723710 SMART SM00451 IPR003604 2983 3017 1.70e-04 Zinc finger, U1-type
XP_003723710 SMART SM00451 IPR003604 3352 3387 3.50e-03 Zinc finger, U1-type
XP_003723710 SMART SM00451 IPR003604 648 682 2.50e-03 Zinc finger, U1-type
XP_003723710 SMART SM00451 IPR003604 879 913 1.40e-02 Zinc finger, U1-type
XP_003723710 SMART SM00451 IPR003604 985 1019 1.50e-04 Zinc finger, U1-type
XP_003723710 SUPERFAMILY SSF46689 IPR009057 2024 2095 0.00e-00 Homeodomain-like
XP_003723710 SUPERFAMILY SSF46689 IPR009057 2331 2408 0.00e-00 Homeodomain-like
XP_003723710 SUPERFAMILY SSF46689 IPR009057 2633 2702 0.00e-00 Homeodomain-like
XP_003723710 SUPERFAMILY SSF46689 IPR009057 2896 2968 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003723710 PF00046 0 Homeobox Homeobox domain
XP_003723710 PF00096 1.1e-25 zf-C2H2 Zinc finger, C2H2 type
XP_003723710 PF13894 4.7e-12 zf-C2H2_4 C2H2-type zinc finger
XP_003723710 PF05920 6.6e-09 Homeobox_KN Homeobox KN domain
XP_003723710 PF12874 2.5e-07 zf-met Zinc-finger of C2H2 type
XP_003723710 PF13912 1.8e-06 zf-C2H2_6 C2H2-type zinc finger
XP_003723710 PF05605 2.2e-05 zf-Di19 Drought induced 19 protein (Di19), zinc-binding
XP_003723710 PF09237 0.0006 GAGA GAGA factor

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003723710 GO:0005634 cellular_component nucleus
XP_003723710 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_003723710 GO:0008270 molecular_function zinc ion binding
XP_003723710 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100116002 132113 Bombus impatiens 100741370
7463 Apis florea 100864500 143995 Megachile rotundata 100877335
9555 Papio anubis 101017132 39432 Saimiri boliviensis 101035646
43179 Ictidomys tridecemlineatus 101970698 10116 Rattus norvegicus 310250
9796 Equus caballus 100054244 7029 Acyrthosiphon pisum 100161293
30195 Bombus terrestris 100650490 10029 Cricetulus griseus 100759927
34638 Metaseiulus occidentalis 100907566 9597 Pan paniscus 100973269
9685 Felis catus 101099345 10090 Mus musculus 11906
7227 Drosophila melanogaster 43795 9646 Ailuropoda melanoleuca ENSAMEG00000002197
9913 Bos taurus ENSBTAG00000033268 10141 Cavia porcellus ENSCPOG00000009111
7955 Danio rerio ENSDARG00000073681 10020 Dipodomys ordii ENSDORG00000016167
9365 Erinaceus europaeus ENSEEUG00000007585 69293 Gasterosteus aculeatus ENSGACG00000002418
9031 Gallus gallus ENSGALG00000000713 9595 Gorilla gorilla ENSGGOG00000012083
7897 Latimeria chalumnae ENSLACG00000015046 9315 Macropus eugenii ENSMEUG00000009090
13616 Monodelphis domestica ENSMODG00000006777 61853 Nomascus leucogenys ENSNLEG00000001972
30611 Otolemur garnettii ENSOGAG00000000486 9601 Pongo abelii ENSPPYG00000007513
9598 Pan troglodytes ENSPTRG00000020358 42254 Sorex araneus ENSSARG00000001090
37347 Tupaia belangeri ENSTBEG00000006524 31033 Takifugu rubripes ENSTRUG00000017601
30538 Vicugna pacos ENSVPAG00000003561 8083 Xiphophorus maculatus ENSXMAG00000000693
7070 Tribolium castaneum 657717 9544 Macaca mulatta 706074
28377 Anolis carolinensis ENSACAG00000008238 9615 Canis familiaris ENSCAFG00000008310
9358 Choloepus hoffmanni ENSCHOG00000002641 9483 Callithrix jacchus ENSCJAG00000015112
51511 Ciona savignyi ENSCSAVG00000009944 9371 Echinops telfairi ENSETEG00000014223
8049 Gadus morhua ENSGMOG00000002909 9785 Loxodonta africana ENSLAFG00000014395
9103 Meleagris gallopavo ENSMGAG00000008764 30608 Microcebus murinus ENSMICG00000003537
59463 Myotis lucifugus ENSMLUG00000016100 9669 Mustela putorius furo ENSMPUG00000007747
9258 Ornithorhynchus anatinus ENSOANG00000005084 9986 Oryctolagus cuniculus ENSOCUG00000017910
8128 Oreochromis niloticus ENSONIG00000005914 9978 Ochotona princeps ENSOPRG00000011379
8090 Oryzias latipes ENSORLG00000007874 9813 Procavia capensis ENSPCAG00000010600
7757 Petromyzon marinus ENSPMAG00000008536 13735 Pelodiscus sinensis ENSPSIG00000003765
132908 Pteropus vampyrus ENSPVAG00000004200 9305 Sarcophilus harrisii ENSSHAG00000014394
9823 Sus scrofa ENSSSCG00000006169 59729 Taeniopygia guttata ENSTGUG00000011605
99883 Tetraodon nigroviridis ENSTNIG00000008122 9478 Tarsius syrichta ENSTSYG00000010369
9739 Tursiops truncatus ENSTTRG00000002634 8364 Xenopus tropicalis ENSXETG00000023509
6239 Caenorhabditis elegans ZC123.3