Basic Information | |||
Gene ID | 20847 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | Stat2 | ||
Full Name | Signal transducer and activator of transcription | ||
Organism | Mus musculus [10090] |
Cross Reference | |||
UniProt | Q9QXJ2 | UniGene | Mm.471333 |
PDB | NULL | OMIM | NULL |
KEGG | mmu:20847 | UCSC | uc007hma.1 |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSMUSP00000082855 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 457 | 578 | 7.60e-45 | EF-hand domain pair |
ENSMUSP00000082855 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 1 | 123 | 4.80e-33 | STAT transcription factor, protein interaction |
ENSMUSP00000082855 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 139 | 316 | 1.80e-44 | STAT transcription factor, all-alpha |
ENSMUSP00000082855 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 317 | 456 | 8.30e-46 | STAT transcription factor, DNA-binding, subdomain |
ENSMUSP00000082855 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 579 | 701 | 4.50e-45 | SH2 domain |
ENSMUSP00000082855 | PANTHER | PTHR11801 | IPR001217 | 2 | 765 | 0.00e-00 | Transcription factor STAT |
ENSMUSP00000082855 | Pfam | PF00017 | IPR000980 | 575 | 646 | 1.90e-10 | SH2 domain |
ENSMUSP00000082855 | Pfam | PF01017 | IPR013800 | 139 | 314 | 1.50e-49 | STAT transcription factor, all-alpha |
ENSMUSP00000082855 | Pfam | PF02864 | IPR013801 | 316 | 564 | 3.10e-94 | STAT transcription factor, DNA-binding |
ENSMUSP00000082855 | Pfam | PF02865 | IPR013799 | 2 | 123 | 3.00e-34 | STAT transcription factor, protein interaction |
ENSMUSP00000082855 | Pfam | PF12188 | IPR022756 | 853 | 907 | 1.50e-25 | Signal transducer and activation of transcription 2, C-terminal |
ENSMUSP00000082855 | ProSiteProfiles | PS50001 | IPR000980 | 570 | 708 | 0.00e-00 | SH2 domain |
ENSMUSP00000082855 | SMART | SM00252 | IPR000980 | 576 | 652 | 2.30e-08 | SH2 domain |
ENSMUSP00000082855 | SMART | SM00964 | IPR013799 | 2 | 124 | 2.80e-58 | STAT transcription factor, protein interaction |
ENSMUSP00000082855 | SUPERFAMILY | SSF47655 | IPR015988 | 137 | 316 | 0.00e-00 | STAT transcription factor, coiled coil |
ENSMUSP00000082855 | SUPERFAMILY | SSF48092 | IPR013799 | 1 | 123 | 0.00e-00 | STAT transcription factor, protein interaction |
ENSMUSP00000082855 | SUPERFAMILY | SSF49417 | IPR008967 | 317 | 565 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSMUSP00000082855 | PF01017 | 0 | STAT_alpha | STAT protein, all-alpha domain |
ENSMUSP00000082855 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
ENSMUSP00000082855 | PF02865 | 3e-34 | STAT_int | STAT protein, protein interaction domain |
ENSMUSP00000082855 | PF12188 | 9.6e-26 | STAT2_C | Signal transducer and activator of transcription 2 C terminal |
ENSMUSP00000082855 | PF00017 | 3.7e-11 | SH2 | SH2 domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSMUSP00000082855 | GO:0006357 | biological_process | regulation of transcription from RNA polymerase II promoter |
ENSMUSP00000082855 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
ENSMUSP00000082855 | GO:0005634 | cellular_component | nucleus |
ENSMUSP00000082855 | GO:0005737 | cellular_component | cytoplasm |
ENSMUSP00000082855 | GO:0003677 | molecular_function | DNA binding |
ENSMUSP00000082855 | GO:0004871 | molecular_function | signal transducer activity |
ENSMUSP00000082855 | GO:0005509 | molecular_function | calcium ion binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9555 | Papio anubis | 101011342 | 39432 | Saimiri boliviensis | 101029836 |
9595 | Gorilla gorilla | 101146695 | 8083 | Xiphophorus maculatus | 102236235 |
61853 | Nomascus leucogenys | 100585171 | 9597 | Pan paniscus | 100972085 |
9606 | Homo sapiens | 6773 | 9544 | Macaca mulatta | 712694 |
28377 | Anolis carolinensis | ENSACAG00000023449 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000003886 |
9913 | Bos taurus | ENSBTAG00000004380 | 9615 | Canis familiaris | ENSCAFG00000000121 |
9358 | Choloepus hoffmanni | ENSCHOG00000012984 | 9483 | Callithrix jacchus | ENSCJAG00000011101 |
10141 | Cavia porcellus | ENSCPOG00000014930 | 9361 | Dasypus novemcinctus | ENSDNOG00000011002 |
10020 | Dipodomys ordii | ENSDORG00000012958 | 9796 | Equus caballus | ENSECAG00000022326 |
9365 | Erinaceus europaeus | ENSEEUG00000010238 | 9685 | Felis catus | ENSFCAG00000012023 |
9785 | Loxodonta africana | ENSLAFG00000014890 | 9315 | Macropus eugenii | ENSMEUG00000010173 |
30608 | Microcebus murinus | ENSMICG00000000089 | 59463 | Myotis lucifugus | ENSMLUG00000006785 |
9669 | Mustela putorius furo | ENSMPUG00000001431 | 9258 | Ornithorhynchus anatinus | ENSOANG00000012739 |
30611 | Otolemur garnettii | ENSOGAG00000001538 | 9978 | Ochotona princeps | ENSOPRG00000001512 |
9813 | Procavia capensis | ENSPCAG00000007855 | 132908 | Pteropus vampyrus | ENSPVAG00000007596 |
9305 | Sarcophilus harrisii | ENSSHAG00000000508 | 9823 | Sus scrofa | ENSSSCG00000000396 |
43179 | Ictidomys tridecemlineatus | ENSSTOG00000015985 | 9478 | Tarsius syrichta | ENSTSYG00000007831 |
9739 | Tursiops truncatus | ENSTTRG00000007159 |