Basic Information
Gene ID 20847 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Stat2
Full Name Signal transducer and activator of transcription
Organism Mus musculus [10090]

Cross Reference
UniProt Q9QXJ2 UniGene Mm.471333
PDB NULL OMIM NULL
KEGG mmu:20847 UCSC uc007hma.1

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000082855 Gene3D G3DSA:1.10.238.10 IPR011992 457 578 7.60e-45 EF-hand domain pair
ENSMUSP00000082855 Gene3D G3DSA:1.10.532.10 IPR013799 1 123 4.80e-33 STAT transcription factor, protein interaction
ENSMUSP00000082855 Gene3D G3DSA:1.20.1050.20 IPR013800 139 316 1.80e-44 STAT transcription factor, all-alpha
ENSMUSP00000082855 Gene3D G3DSA:2.60.40.630 IPR012345 317 456 8.30e-46 STAT transcription factor, DNA-binding, subdomain
ENSMUSP00000082855 Gene3D G3DSA:3.30.505.10 IPR000980 579 701 4.50e-45 SH2 domain
ENSMUSP00000082855 PANTHER PTHR11801 IPR001217 2 765 0.00e-00 Transcription factor STAT
ENSMUSP00000082855 Pfam PF00017 IPR000980 575 646 1.90e-10 SH2 domain
ENSMUSP00000082855 Pfam PF01017 IPR013800 139 314 1.50e-49 STAT transcription factor, all-alpha
ENSMUSP00000082855 Pfam PF02864 IPR013801 316 564 3.10e-94 STAT transcription factor, DNA-binding
ENSMUSP00000082855 Pfam PF02865 IPR013799 2 123 3.00e-34 STAT transcription factor, protein interaction
ENSMUSP00000082855 Pfam PF12188 IPR022756 853 907 1.50e-25 Signal transducer and activation of transcription 2, C-terminal
ENSMUSP00000082855 ProSiteProfiles PS50001 IPR000980 570 708 0.00e-00 SH2 domain
ENSMUSP00000082855 SMART SM00252 IPR000980 576 652 2.30e-08 SH2 domain
ENSMUSP00000082855 SMART SM00964 IPR013799 2 124 2.80e-58 STAT transcription factor, protein interaction
ENSMUSP00000082855 SUPERFAMILY SSF47655 IPR015988 137 316 0.00e-00 STAT transcription factor, coiled coil
ENSMUSP00000082855 SUPERFAMILY SSF48092 IPR013799 1 123 0.00e-00 STAT transcription factor, protein interaction
ENSMUSP00000082855 SUPERFAMILY SSF49417 IPR008967 317 565 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000082855 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSMUSP00000082855 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSMUSP00000082855 PF02865 3e-34 STAT_int STAT protein, protein interaction domain
ENSMUSP00000082855 PF12188 9.6e-26 STAT2_C Signal transducer and activator of transcription 2 C terminal
ENSMUSP00000082855 PF00017 3.7e-11 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000082855 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSMUSP00000082855 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSMUSP00000082855 GO:0005634 cellular_component nucleus
ENSMUSP00000082855 GO:0005737 cellular_component cytoplasm
ENSMUSP00000082855 GO:0003677 molecular_function DNA binding
ENSMUSP00000082855 GO:0004871 molecular_function signal transducer activity
ENSMUSP00000082855 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9555 Papio anubis 101011342 39432 Saimiri boliviensis 101029836
9595 Gorilla gorilla 101146695 8083 Xiphophorus maculatus 102236235
61853 Nomascus leucogenys 100585171 9597 Pan paniscus 100972085
9606 Homo sapiens 6773 9544 Macaca mulatta 712694
28377 Anolis carolinensis ENSACAG00000023449 9646 Ailuropoda melanoleuca ENSAMEG00000003886
9913 Bos taurus ENSBTAG00000004380 9615 Canis familiaris ENSCAFG00000000121
9358 Choloepus hoffmanni ENSCHOG00000012984 9483 Callithrix jacchus ENSCJAG00000011101
10141 Cavia porcellus ENSCPOG00000014930 9361 Dasypus novemcinctus ENSDNOG00000011002
10020 Dipodomys ordii ENSDORG00000012958 9796 Equus caballus ENSECAG00000022326
9365 Erinaceus europaeus ENSEEUG00000010238 9685 Felis catus ENSFCAG00000012023
9785 Loxodonta africana ENSLAFG00000014890 9315 Macropus eugenii ENSMEUG00000010173
30608 Microcebus murinus ENSMICG00000000089 59463 Myotis lucifugus ENSMLUG00000006785
9669 Mustela putorius furo ENSMPUG00000001431 9258 Ornithorhynchus anatinus ENSOANG00000012739
30611 Otolemur garnettii ENSOGAG00000001538 9978 Ochotona princeps ENSOPRG00000001512
9813 Procavia capensis ENSPCAG00000007855 132908 Pteropus vampyrus ENSPVAG00000007596
9305 Sarcophilus harrisii ENSSHAG00000000508 9823 Sus scrofa ENSSSCG00000000396
43179 Ictidomys tridecemlineatus ENSSTOG00000015985 9478 Tarsius syrichta ENSTSYG00000007831
9739 Tursiops truncatus ENSTTRG00000007159