Basic Information
Gene ID ENSLAFG00000014890
Gene Name NULL
Full Name Signal transducer and activator of transcription
Organism Loxodonta africana [9785]

Cross Reference
UniProt G3TE30 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSLAFP00000012473 Gene3D G3DSA:1.10.238.10 IPR011992 464 584 4.70e-43 EF-hand domain pair
ENSLAFP00000012473 Gene3D G3DSA:1.10.532.10 IPR013799 1 124 1.90e-34 STAT transcription factor, protein interaction
ENSLAFP00000012473 Gene3D G3DSA:1.20.1050.20 IPR013800 141 316 3.00e-52 STAT transcription factor, all-alpha
ENSLAFP00000012473 Gene3D G3DSA:2.60.40.630 IPR012345 322 463 9.90e-49 STAT transcription factor, DNA-binding, subdomain
ENSLAFP00000012473 Gene3D G3DSA:3.30.505.10 IPR000980 585 705 1.70e-43 SH2 domain
ENSLAFP00000012473 PANTHER PTHR11801 IPR001217 2 782 0.00e-00 Transcription factor STAT
ENSLAFP00000012473 Pfam PF00017 IPR000980 581 652 1.30e-10 SH2 domain
ENSLAFP00000012473 Pfam PF01017 IPR013800 141 315 1.00e-48 STAT transcription factor, all-alpha
ENSLAFP00000012473 Pfam PF02864 IPR013801 321 570 1.80e-97 STAT transcription factor, DNA-binding
ENSLAFP00000012473 Pfam PF02865 IPR013799 2 124 4.20e-36 STAT transcription factor, protein interaction
ENSLAFP00000012473 Pfam PF12188 IPR022756 773 828 2.20e-21 Signal transducer and activation of transcription 2, C-terminal
ENSLAFP00000012473 ProSiteProfiles PS50001 IPR000980 576 671 0.00e-00 SH2 domain
ENSLAFP00000012473 SMART SM00252 IPR000980 578 658 1.40e-08 SH2 domain
ENSLAFP00000012473 SMART SM00964 IPR013799 2 125 6.60e-60 STAT transcription factor, protein interaction
ENSLAFP00000012473 SUPERFAMILY SSF47655 IPR015988 140 316 0.00e-00 STAT transcription factor, coiled coil
ENSLAFP00000012473 SUPERFAMILY SSF48092 IPR013799 1 124 0.00e-00 STAT transcription factor, protein interaction
ENSLAFP00000012473 SUPERFAMILY SSF49417 IPR008967 322 571 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSLAFP00000012473 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSLAFP00000012473 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSLAFP00000012473 PF02865 4.2e-36 STAT_int STAT protein, protein interaction domain
ENSLAFP00000012473 PF12188 9e-22 STAT2_C Signal transducer and activator of transcription 2 C terminal
ENSLAFP00000012473 PF00017 5.3e-11 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSLAFP00000012473 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSLAFP00000012473 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSLAFP00000012473 GO:0005634 cellular_component nucleus
ENSLAFP00000012473 GO:0005737 cellular_component cytoplasm
ENSLAFP00000012473 GO:0003677 molecular_function DNA binding
ENSLAFP00000012473 GO:0004871 molecular_function signal transducer activity
ENSLAFP00000012473 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9595 Gorilla gorilla 101146695 28377 Anolis carolinensis ENSACAG00000023449
9913 Bos taurus ENSBTAG00000004380 9358 Choloepus hoffmanni ENSCHOG00000012984
10141 Cavia porcellus ENSCPOG00000014930 9365 Erinaceus europaeus ENSEEUG00000010238
61853 Nomascus leucogenys 100585171 9597 Pan paniscus 100972085
9555 Papio anubis 101011342 39432 Saimiri boliviensis 101029836
10090 Mus musculus 20847 9606 Homo sapiens 6773
9544 Macaca mulatta 712694 9646 Ailuropoda melanoleuca ENSAMEG00000003886
9615 Canis familiaris ENSCAFG00000000121 9483 Callithrix jacchus ENSCJAG00000011101
9361 Dasypus novemcinctus ENSDNOG00000011002 10020 Dipodomys ordii ENSDORG00000012958
9796 Equus caballus ENSECAG00000022326 9685 Felis catus ENSFCAG00000012023
9315 Macropus eugenii ENSMEUG00000010173 30608 Microcebus murinus ENSMICG00000000089
59463 Myotis lucifugus ENSMLUG00000006785 9669 Mustela putorius furo ENSMPUG00000001431
9258 Ornithorhynchus anatinus ENSOANG00000012739 30611 Otolemur garnettii ENSOGAG00000001538
9978 Ochotona princeps ENSOPRG00000001512 9813 Procavia capensis ENSPCAG00000007855
9823 Sus scrofa ENSSSCG00000000396 43179 Ictidomys tridecemlineatus ENSSTOG00000015985
30538 Vicugna pacos ENSVPAG00000007311 132908 Pteropus vampyrus ENSPVAG00000007596
9305 Sarcophilus harrisii ENSSHAG00000000508 9478 Tarsius syrichta ENSTSYG00000007831
9739 Tursiops truncatus ENSTTRG00000007159