Basic Information
Gene ID 373533
Gene Name NFkB
Full Name NFkB
Organism Strongylocentrotus purpuratus [7668]

Cross Reference
UniProt O96458 UniGene Spu.162
PDB NULL OMIM NULL
KEGG spu:373533 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 7668.O96458

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_999819 Gene3D G3DSA:1.10.533.10 IPR011029 999 1089 2.40e-16 Death-like domain
NP_999819 Gene3D G3DSA:1.25.40.20 IPR020683 626 871 1.40e-51 Ankyrin repeat-containing domain
NP_999819 Gene3D G3DSA:1.25.40.20 IPR020683 907 923 1.40e-51 Ankyrin repeat-containing domain
NP_999819 Gene3D G3DSA:2.60.40.10 IPR013783 256 374 9.70e-48 Immunoglobulin-like fold
NP_999819 Gene3D G3DSA:2.60.40.340 IPR011539 59 251 1.10e-69 Rel homology domain
NP_999819 Pfam PF00023 IPR002110 696 725 4.20e-08 Ankyrin repeat
NP_999819 Pfam PF00023 IPR002110 728 749 1.60e-02 Ankyrin repeat
NP_999819 Pfam PF00023 IPR002110 771 801 8.10e-05 Ankyrin repeat
NP_999819 Pfam PF00023 IPR002110 838 868 2.20e-03 Ankyrin repeat
NP_999819 Pfam PF00531 IPR000488 1021 1087 9.40e-07 Death domain
NP_999819 Pfam PF00554 IPR011539 62 250 5.40e-71 Rel homology domain
NP_999819 PRINTS PR00057 IPR000451 239 253 4.90e-40 NF-kappa-B/Rel/Dorsal
NP_999819 PRINTS PR00057 IPR000451 272 292 4.90e-40 NF-kappa-B/Rel/Dorsal
NP_999819 PRINTS PR00057 IPR000451 309 327 4.90e-40 NF-kappa-B/Rel/Dorsal
NP_999819 PRINTS PR00057 IPR000451 350 364 4.90e-40 NF-kappa-B/Rel/Dorsal
NP_999819 PRINTS PR00057 IPR000451 66 83 4.90e-40 NF-kappa-B/Rel/Dorsal
NP_999819 PRINTS PR01415 IPR002110 728 743 3.50e-05 Ankyrin repeat
NP_999819 PRINTS PR01415 IPR002110 786 800 3.50e-05 Ankyrin repeat
NP_999819 ProSitePatterns PS01204 IPR000451 75 81 - NF-kappa-B/Rel/Dorsal
NP_999819 ProSiteProfiles PS50088 IPR002110 694 726 0.00e-00 Ankyrin repeat
NP_999819 ProSiteProfiles PS50088 IPR002110 727 749 0.00e-00 Ankyrin repeat
NP_999819 ProSiteProfiles PS50088 IPR002110 770 802 0.00e-00 Ankyrin repeat
NP_999819 ProSiteProfiles PS50088 IPR002110 804 837 0.00e-00 Ankyrin repeat
NP_999819 ProSiteProfiles PS50088 IPR002110 838 870 0.00e-00 Ankyrin repeat
NP_999819 ProSiteProfiles PS50254 IPR011539 57 254 0.00e-00 Rel homology domain
NP_999819 ProSiteProfiles PS50297 IPR020683 655 870 0.00e-00 Ankyrin repeat-containing domain
NP_999819 SMART SM00005 IPR000488 1000 1088 1.30e-16 Death domain
NP_999819 SMART SM00248 IPR002110 624 653 8.90e+00 Ankyrin repeat
NP_999819 SMART SM00248 IPR002110 655 684 1.40e-04 Ankyrin repeat
NP_999819 SMART SM00248 IPR002110 694 723 6.20e-07 Ankyrin repeat
NP_999819 SMART SM00248 IPR002110 727 756 1.10e-02 Ankyrin repeat
NP_999819 SMART SM00248 IPR002110 770 799 1.10e-06 Ankyrin repeat
NP_999819 SMART SM00248 IPR002110 804 834 3.00e-03 Ankyrin repeat
NP_999819 SMART SM00248 IPR002110 838 867 2.50e-02 Ankyrin repeat
NP_999819 SMART SM00429 IPR002909 257 359 8.90e-30 IPT domain
NP_999819 SUPERFAMILY SSF47986 IPR011029 1005 1086 0.00e-00 Death-like domain
NP_999819 SUPERFAMILY SSF48403 IPR020683 655 876 0.00e-00 Ankyrin repeat-containing domain
NP_999819 SUPERFAMILY SSF49417 IPR008967 59 260 0.00e-00 p53-like transcription factor, DNA-binding
NP_999819 SUPERFAMILY SSF81296 IPR014756 257 391 0.00e-00 Immunoglobulin E-set

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_999819 PF00554 0 RHD Rel homology domain (RHD)
NP_999819 PF12796 1.9e-39 Ank_2 Ankyrin repeats (3 copies)
NP_999819 PF00023 5.8e-33 Ank Ankyrin repeat
NP_999819 PF13637 2.9e-26 Ank_4 Ankyrin repeats (many copies)
NP_999819 PF13606 6.1e-24 Ank_3 Ankyrin repeat
NP_999819 PF13857 2.6e-21 Ank_5 Ankyrin repeats (many copies)
NP_999819 PF00531 2.8e-07 Death Death domain

Gene Ontology Annotation
Protein Entry Name Space Description
NP_999819 GO:0006351 biological_process transcription, DNA-templated
NP_999819 GO:0005634 cellular_component nucleus
NP_999819 GO:0005737 cellular_component cytoplasm
NP_999819 GO:0003677 molecular_function DNA binding
NP_999819 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100118783 7463 Apis florea 100863692
39432 Saimiri boliviensis 101035787 7029 Acyrthosiphon pisum 100162436
10224 Saccoglossus kowalevskii 100303565 61853 Nomascus leucogenys 100581655
400682 Amphimedon queenslandica 100616089 30195 Bombus terrestris 100631054
132113 Bombus impatiens 100741932 10029 Cricetulus griseus 100756087
143995 Megachile rotundata 100876069 9597 Pan paniscus 100979341
9555 Papio anubis 101026781 9595 Gorilla gorilla 101131033
43179 Ictidomys tridecemlineatus 101972573 59463 Myotis lucifugus 102435748
10090 Mus musculus 18034 7227 Drosophila melanogaster 35047
7955 Danio rerio 415100 9598 Pan troglodytes 470380
9544 Macaca mulatta 710324 10116 Rattus norvegicus 81736
9646 Ailuropoda melanoleuca ENSAMEG00000008882 9913 Bos taurus ENSBTAG00000020270
9615 Canis familiaris ENSCAFG00000010730 9358 Choloepus hoffmanni ENSCHOG00000010935
7719 Ciona intestinalis ENSCING00000006933 9483 Callithrix jacchus ENSCJAG00000017928
10141 Cavia porcellus ENSCPOG00000007789 51511 Ciona savignyi ENSCSAVG00000003063
9361 Dasypus novemcinctus ENSDNOG00000006855 10020 Dipodomys ordii ENSDORG00000007447
9796 Equus caballus ENSECAG00000015042 9365 Erinaceus europaeus ENSEEUG00000002921
9371 Echinops telfairi ENSETEG00000007738 9685 Felis catus ENSFCAG00000007557
9031 Gallus gallus ENSGALG00000005653 8049 Gadus morhua ENSGMOG00000007506
7897 Latimeria chalumnae ENSLACG00000002751 9785 Loxodonta africana ENSLAFG00000009344
9315 Macropus eugenii ENSMEUG00000001334 9103 Meleagris gallopavo ENSMGAG00000011299
30608 Microcebus murinus ENSMICG00000011856 9669 Mustela putorius furo ENSMPUG00000009413
9258 Ornithorhynchus anatinus ENSOANG00000022123 9986 Oryctolagus cuniculus ENSOCUG00000021712
30611 Otolemur garnettii ENSOGAG00000016379 8128 Oreochromis niloticus ENSONIG00000004349
9978 Ochotona princeps ENSOPRG00000005212 8090 Oryzias latipes ENSORLG00000002942
9813 Procavia capensis ENSPCAG00000008172 7757 Petromyzon marinus ENSPMAG00000006461
9601 Pongo abelii ENSPPYG00000014965 13735 Pelodiscus sinensis ENSPSIG00000008515
132908 Pteropus vampyrus ENSPVAG00000002722 42254 Sorex araneus ENSSARG00000003535
9823 Sus scrofa ENSSSCG00000010580 37347 Tupaia belangeri ENSTBEG00000003520
59729 Taeniopygia guttata ENSTGUG00000003595 99883 Tetraodon nigroviridis ENSTNIG00000002693
31033 Takifugu rubripes ENSTRUG00000004360 9739 Tursiops truncatus ENSTTRG00000010852
30538 Vicugna pacos ENSVPAG00000000280 8364 Xenopus tropicalis ENSXETG00000021325
8083 Xiphophorus maculatus ENSXMAG00000015369 7460 Apis mellifera 406086
9606 Homo sapiens 4790 7070 Tribolium castaneum 641547
28377 Anolis carolinensis ENSACAG00000014215 69293 Gasterosteus aculeatus ENSGACG00000016876
13616 Monodelphis domestica ENSMODG00000020672 9305 Sarcophilus harrisii ENSSHAG00000007374
9478 Tarsius syrichta ENSTSYG00000012918