Basic Information
Gene ID 5915 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name RARB; HAP, NR1B2
Full Name Retinoic acid receptor beta
Organism Homo sapiens [9606]

Cross Reference
UniProt P10826 UniGene Hs.733004
PDB 4DM8 OMIM 180220
KEGG hsa:5915 UCSC uc003cdi.2

Protein Interactions
DIP NULL
IntAct P10826
MINT MINT-1180428
STRING 9606.ENSP00000332296

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000385865 Gene3D G3DSA:1.10.565.10 IPR008946 160 416 3.40e-91 Nuclear hormone receptor, ligand-binding
ENSP00000385865 Gene3D G3DSA:3.30.50.10 IPR013088 85 159 2.60e-33 Zinc finger, NHR/GATA-type
ENSP00000385865 Pfam PF00104 IPR000536 225 394 3.50e-32 Nuclear hormone receptor, ligand-binding, core
ENSP00000385865 Pfam PF00105 IPR001628 87 155 1.60e-32 Zinc finger, nuclear hormone receptor-type
ENSP00000385865 PRINTS PR00047 IPR001628 104 119 5.30e-19 Zinc finger, nuclear hormone receptor-type
ENSP00000385865 PRINTS PR00047 IPR001628 137 145 5.30e-19 Zinc finger, nuclear hormone receptor-type
ENSP00000385865 PRINTS PR00047 IPR001628 145 153 5.30e-19 Zinc finger, nuclear hormone receptor-type
ENSP00000385865 PRINTS PR00047 IPR001628 88 104 5.30e-19 Zinc finger, nuclear hormone receptor-type
ENSP00000385865 PRINTS PR00398 IPR001723 149 159 3.10e-35 Steroid hormone receptor
ENSP00000385865 PRINTS PR00398 IPR001723 231 252 3.10e-35 Steroid hormone receptor
ENSP00000385865 PRINTS PR00398 IPR001723 252 268 3.10e-35 Steroid hormone receptor
ENSP00000385865 PRINTS PR00398 IPR001723 319 334 3.10e-35 Steroid hormone receptor
ENSP00000385865 PRINTS PR00398 IPR001723 376 393 3.10e-35 Steroid hormone receptor
ENSP00000385865 PRINTS PR01292 IPR003078 154 167 1.50e-103 Retinoic acid receptor
ENSP00000385865 PRINTS PR01292 IPR003078 176 200 1.50e-103 Retinoic acid receptor
ENSP00000385865 PRINTS PR01292 IPR003078 201 217 1.50e-103 Retinoic acid receptor
ENSP00000385865 PRINTS PR01292 IPR003078 223 240 1.50e-103 Retinoic acid receptor
ENSP00000385865 PRINTS PR01292 IPR003078 274 298 1.50e-103 Retinoic acid receptor
ENSP00000385865 PRINTS PR01292 IPR003078 311 323 1.50e-103 Retinoic acid receptor
ENSP00000385865 PRINTS PR01292 IPR003078 341 362 1.50e-103 Retinoic acid receptor
ENSP00000385865 PRINTS PR01292 IPR003078 385 400 1.50e-103 Retinoic acid receptor
ENSP00000385865 PRINTS PR01292 IPR003078 408 421 1.50e-103 Retinoic acid receptor
ENSP00000385865 PRINTS PR01292 IPR003078 60 77 1.50e-103 Retinoic acid receptor
ENSP00000385865 ProSitePatterns PS00031 IPR001628 88 114 - Zinc finger, nuclear hormone receptor-type
ENSP00000385865 ProSiteProfiles PS51030 IPR001628 85 160 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSP00000385865 SMART SM00399 IPR001628 85 156 1.20e-42 Zinc finger, nuclear hormone receptor-type
ENSP00000385865 SMART SM00430 IPR000536 230 388 5.70e-37 Nuclear hormone receptor, ligand-binding, core
ENSP00000385865 SUPERFAMILY SSF48508 IPR008946 137 415 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000385865 PF00105 1.6e-32 zf-C4 Zinc finger, C4 type (two domains)
ENSP00000385865 PF00104 1.7e-32 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000385865 GO:0005634 cellular_component nucleus
ENSP00000385865 GO:0003707 molecular_function steroid hormone receptor activity
ENSP00000385865 GO:0003708 molecular_function retinoic acid receptor activity
ENSP00000385865 GO:0008270 molecular_function zinc ion binding
ENSP00000385865 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100768698 34638 Metaseiulus occidentalis 100899165
9669 Mustela putorius furo 101671927 7897 Latimeria chalumnae 102356597
59463 Myotis lucifugus 102425322 10090 Mus musculus 218772
10116 Rattus norvegicus 24706 7668 Strongylocentrotus purpuratus 574567
7029 Acyrthosiphon pisum 100166941 9103 Meleagris gallopavo 100545327
9597 Pan paniscus 100992361 9555 Papio anubis 101010670
39432 Saimiri boliviensis 101053144 9685 Felis catus 101085742
13735 Pelodiscus sinensis 102448036 9031 Gallus gallus 396266
9598 Pan troglodytes 745516 9358 Choloepus hoffmanni ENSCHOG00000008395
7719 Ciona intestinalis ENSCING00000006945 10141 Cavia porcellus ENSCPOG00000015410
51511 Ciona savignyi ENSCSAVG00000006794 9595 Gorilla gorilla ENSGGOG00000002331
8049 Gadus morhua ENSGMOG00000017824 9785 Loxodonta africana ENSLAFG00000015824
30608 Microcebus murinus ENSMICG00000013447 9544 Macaca mulatta ENSMMUG00000007367
13616 Monodelphis domestica ENSMODG00000014926 9986 Oryctolagus cuniculus ENSOCUG00000000714
7757 Petromyzon marinus ENSPMAG00000000088 9601 Pongo abelii ENSPPYG00000014062
132908 Pteropus vampyrus ENSPVAG00000012533 9305 Sarcophilus harrisii ENSSHAG00000009801
9823 Sus scrofa ENSSSCG00000011212 8083 Xiphophorus maculatus ENSXMAG00000017035
59729 Taeniopygia guttata 778446 9646 Ailuropoda melanoleuca ENSAMEG00000000740
9913 Bos taurus ENSBTAG00000011518 9483 Callithrix jacchus ENSCJAG00000003911
9361 Dasypus novemcinctus ENSDNOG00000010433 9796 Equus caballus ENSECAG00000016976
9365 Erinaceus europaeus ENSEEUG00000006140 9258 Ornithorhynchus anatinus ENSOANG00000012236
8090 Oryzias latipes ENSORLG00000008502 42254 Sorex araneus ENSSARG00000003129
9478 Tarsius syrichta ENSTSYG00000008658 30538 Vicugna pacos ENSVPAG00000009206
8364 Xenopus tropicalis ENSXETG00000007272

Paralogs
5914 5916