Basic Information
Gene ID 6658 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name SOX3
Full Name Transcription factor SOX-3
Organism Homo sapiens [9606]

Cross Reference
UniProt P41225 UniGene Hs.157429
PDB NULL OMIM 313430
KEGG hsa:6658 UCSC uc004fbd.1

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9606.ENSP00000359567

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000359567 Gene3D G3DSA:1.10.30.10 IPR009071 138 217 3.40e-39 High mobility group box domain
ENSP00000359567 Pfam PF00505 IPR009071 139 207 5.00e-26 High mobility group box domain
ENSP00000359567 Pfam PF12336 IPR022097 208 289 2.70e-22 Transcription factor SOX
ENSP00000359567 ProSiteProfiles PS50118 IPR009071 139 207 0.00e-00 High mobility group box domain
ENSP00000359567 SMART SM00398 IPR009071 138 208 1.10e-31 High mobility group box domain
ENSP00000359567 SUPERFAMILY SSF47095 IPR009071 134 224 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000359567 PF00505 3.3e-26 HMG_box HMG (high mobility group) box
ENSP00000359567 PF12336 2.7e-22 SOXp SOX transcription factor
ENSP00000359567 PF09011 6.4e-10 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000359567 GO:0006351 biological_process transcription, DNA-templated
ENSP00000359567 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000359567 GO:0007275 biological_process multicellular organismal development
ENSP00000359567 GO:0005634 cellular_component nucleus
ENSP00000359567 GO:0003677 molecular_function DNA binding
ENSP00000359567 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7897 Latimeria chalumnae 102345911 9823 Sus scrofa 100623770
9555 Papio anubis 101023632 13735 Pelodiscus sinensis 102464046
10141 Cavia porcellus ENSCPOG00000022456 9785 Loxodonta africana ENSLAFG00000030155
59463 Myotis lucifugus ENSMLUG00000000946 9669 Mustela putorius furo ENSMPUG00000001759
9813 Procavia capensis ENSPCAG00000009165 9601 Pongo abelii ENSPPYG00000020784
132908 Pteropus vampyrus ENSPVAG00000003166 9544 Macaca mulatta 696412
9483 Callithrix jacchus ENSCJAG00000022387 9595 Gorilla gorilla ENSGGOG00000008130
9986 Oryctolagus cuniculus ENSOCUG00000016779 30611 Otolemur garnettii ENSOGAG00000025781
9305 Sarcophilus harrisii ENSSHAG00000007719