Basic Information
Gene ID ENSLACG00000002646
Gene Name NULL
Full Name Signal transducer and activator of transcription
Organism Latimeria chalumnae [7897]

Cross Reference
UniProt H2ZZY6 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSLACP00000002958 Gene3D G3DSA:1.10.238.10 IPR011992 473 598 5.70e-47 EF-hand domain pair
ENSLACP00000002958 Gene3D G3DSA:1.10.532.10 IPR013799 1 124 4.10e-28 STAT transcription factor, protein interaction
ENSLACP00000002958 Gene3D G3DSA:1.20.1050.20 IPR013800 138 333 2.00e-60 STAT transcription factor, all-alpha
ENSLACP00000002958 Gene3D G3DSA:2.60.40.630 IPR012345 334 472 9.00e-68 STAT transcription factor, DNA-binding, subdomain
ENSLACP00000002958 Gene3D G3DSA:3.30.505.10 IPR000980 599 711 9.30e-44 SH2 domain
ENSLACP00000002958 PANTHER PTHR11801 IPR001217 2 779 0.00e-00 Transcription factor STAT
ENSLACP00000002958 Pfam PF00017 IPR000980 596 675 1.40e-10 SH2 domain
ENSLACP00000002958 Pfam PF01017 IPR013800 137 331 5.50e-53 STAT transcription factor, all-alpha
ENSLACP00000002958 Pfam PF02864 IPR013801 333 584 4.30e-95 STAT transcription factor, DNA-binding
ENSLACP00000002958 Pfam PF02865 IPR013799 2 124 3.10e-27 STAT transcription factor, protein interaction
ENSLACP00000002958 ProSiteProfiles PS50001 IPR000980 590 691 0.00e-00 SH2 domain
ENSLACP00000002958 SMART SM00252 IPR000980 588 681 8.00e-09 SH2 domain
ENSLACP00000002958 SUPERFAMILY SSF47655 IPR015988 136 333 0.00e-00 STAT transcription factor, coiled coil
ENSLACP00000002958 SUPERFAMILY SSF48092 IPR013799 1 123 0.00e-00 STAT transcription factor, protein interaction
ENSLACP00000002958 SUPERFAMILY SSF49417 IPR008967 327 585 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSLACP00000002958 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSLACP00000002958 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSLACP00000002958 PF02865 3.1e-27 STAT_int STAT protein, protein interaction domain
ENSLACP00000002958 PF00017 2.1e-11 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSLACP00000002958 GO:0001553 biological_process luteinization
ENSLACP00000002958 GO:0001779 biological_process natural killer cell differentiation
ENSLACP00000002958 GO:0006351 biological_process transcription, DNA-templated
ENSLACP00000002958 GO:0007259 biological_process JAK-STAT cascade
ENSLACP00000002958 GO:0007565 biological_process female pregnancy
ENSLACP00000002958 GO:0007595 biological_process lactation
ENSLACP00000002958 GO:0019218 biological_process regulation of steroid metabolic process
ENSLACP00000002958 GO:0019915 biological_process lipid storage
ENSLACP00000002958 GO:0030155 biological_process regulation of cell adhesion
ENSLACP00000002958 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSLACP00000002958 GO:0038161 biological_process prolactin signaling pathway
ENSLACP00000002958 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSLACP00000002958 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSLACP00000002958 GO:0043029 biological_process T cell homeostasis
ENSLACP00000002958 GO:0043066 biological_process negative regulation of apoptotic process
ENSLACP00000002958 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSLACP00000002958 GO:0045579 biological_process positive regulation of B cell differentiation
ENSLACP00000002958 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSLACP00000002958 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSLACP00000002958 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSLACP00000002958 GO:0046543 biological_process development of secondary female sexual characteristics
ENSLACP00000002958 GO:0050729 biological_process positive regulation of inflammatory response
ENSLACP00000002958 GO:0005634 cellular_component nucleus
ENSLACP00000002958 GO:0005737 cellular_component cytoplasm
ENSLACP00000002958 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSLACP00000002958 GO:0004871 molecular_function signal transducer activity
ENSLACP00000002958 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100012174 7425 Nasonia vitripennis 100121885
7029 Acyrthosiphon pisum 100161101 6087 Hydra magnipapillata 100206878
9986 Oryctolagus cuniculus 100348267 9601 Pongo abelii 100462537
400682 Amphimedon queenslandica 100641588 30195 Bombus terrestris 100647789
132113 Bombus impatiens 100743540 10029 Cricetulus griseus 100755571
7463 Apis florea 100864112 143995 Megachile rotundata 100880948
34638 Metaseiulus occidentalis 100907258 30611 Otolemur garnettii 100958999
9597 Pan paniscus 100989105 9555 Papio anubis 101000002
39432 Saimiri boliviensis 101043203 9669 Mustela putorius furo 101691575
10090 Mus musculus 20851 10116 Rattus norvegicus 25126
9031 Gallus gallus 395556 9823 Sus scrofa 397340
7460 Apis mellifera 413742 7227 Drosophila melanogaster 42428
9598 Pan troglodytes 454681 9544 Macaca mulatta 574129
7668 Strongylocentrotus purpuratus 576433 7070 Tribolium castaneum 657965
7719 Ciona intestinalis 778770 28377 Anolis carolinensis ENSACAG00000009680
9646 Ailuropoda melanoleuca ENSAMEG00000006061 9913 Bos taurus ENSBTAG00000009496
9615 Canis familiaris ENSCAFG00000015509 9358 Choloepus hoffmanni ENSCHOG00000005387
9483 Callithrix jacchus ENSCJAG00000000426 10141 Cavia porcellus ENSCPOG00000026466
51511 Ciona savignyi ENSCSAVG00000011110 7955 Danio rerio ENSDARG00000019392
9361 Dasypus novemcinctus ENSDNOG00000007398 10020 Dipodomys ordii ENSDORG00000000303
9796 Equus caballus ENSECAG00000007847 9365 Erinaceus europaeus ENSEEUG00000003642
9371 Echinops telfairi ENSETEG00000008535 9685 Felis catus ENSFCAG00000002153
69293 Gasterosteus aculeatus ENSGACG00000008634 9595 Gorilla gorilla ENSGGOG00000008216
8049 Gadus morhua ENSGMOG00000014154 9785 Loxodonta africana ENSLAFG00000014055
9315 Macropus eugenii ENSMEUG00000006640 9103 Meleagris gallopavo ENSMGAG00000003430
30608 Microcebus murinus ENSMICG00000011988 59463 Myotis lucifugus ENSMLUG00000012050
61853 Nomascus leucogenys ENSNLEG00000011444 9258 Ornithorhynchus anatinus ENSOANG00000006496
8128 Oreochromis niloticus ENSONIG00000007261 9978 Ochotona princeps ENSOPRG00000008312
8090 Oryzias latipes ENSORLG00000003961 9813 Procavia capensis ENSPCAG00000010107
7757 Petromyzon marinus ENSPMAG00000009008 13735 Pelodiscus sinensis ENSPSIG00000015138
132908 Pteropus vampyrus ENSPVAG00000003876 42254 Sorex araneus ENSSARG00000014205
43179 Ictidomys tridecemlineatus ENSSTOG00000006691 37347 Tupaia belangeri ENSTBEG00000009608
59729 Taeniopygia guttata ENSTGUG00000002572 99883 Tetraodon nigroviridis ENSTNIG00000011707
31033 Takifugu rubripes ENSTRUG00000015454 9478 Tarsius syrichta ENSTSYG00000000267
9739 Tursiops truncatus ENSTTRG00000006684 30538 Vicugna pacos ENSVPAG00000005450
8364 Xenopus tropicalis ENSXETG00000000836 8083 Xiphophorus maculatus ENSXMAG00000005165