Basic Information
Gene ID ENSLAFG00000014055
Gene Name LOC100672448
Full Name Signal transducer and activator of transcription
Organism Loxodonta africana [9785]

Cross Reference
UniProt G3TCH9 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSLAFP00000011770 Gene3D G3DSA:1.10.238.10 IPR011992 472 597 3.90e-46 EF-hand domain pair
ENSLAFP00000011770 Gene3D G3DSA:1.10.532.10 IPR013799 1 104 6.80e-39 STAT transcription factor, protein interaction
ENSLAFP00000011770 Gene3D G3DSA:1.20.1050.20 IPR013800 140 332 1.60e-62 STAT transcription factor, all-alpha
ENSLAFP00000011770 Gene3D G3DSA:2.60.40.630 IPR012345 333 471 2.60e-69 STAT transcription factor, DNA-binding, subdomain
ENSLAFP00000011770 Gene3D G3DSA:3.30.505.10 IPR000980 598 707 7.00e-40 SH2 domain
ENSLAFP00000011770 PANTHER PTHR11801 IPR001217 2 774 0.00e-00 Transcription factor STAT
ENSLAFP00000011770 Pfam PF00017 IPR000980 595 669 1.00e-10 SH2 domain
ENSLAFP00000011770 Pfam PF01017 IPR013800 139 330 1.60e-51 STAT transcription factor, all-alpha
ENSLAFP00000011770 Pfam PF02864 IPR013801 332 583 6.60e-99 STAT transcription factor, DNA-binding
ENSLAFP00000011770 Pfam PF02865 IPR013799 2 104 9.30e-39 STAT transcription factor, protein interaction
ENSLAFP00000011770 ProSiteProfiles PS50001 IPR000980 589 686 0.00e-00 SH2 domain
ENSLAFP00000011770 SMART SM00252 IPR000980 587 700 2.30e-08 SH2 domain
ENSLAFP00000011770 SMART SM00964 IPR013799 2 127 8.70e-47 STAT transcription factor, protein interaction
ENSLAFP00000011770 SUPERFAMILY SSF47655 IPR015988 137 332 0.00e-00 STAT transcription factor, coiled coil
ENSLAFP00000011770 SUPERFAMILY SSF48092 IPR013799 1 104 0.00e-00 STAT transcription factor, protein interaction
ENSLAFP00000011770 SUPERFAMILY SSF49417 IPR008967 327 584 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSLAFP00000011770 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSLAFP00000011770 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSLAFP00000011770 PF02865 9.3e-39 STAT_int STAT protein, protein interaction domain
ENSLAFP00000011770 PF00017 1.3e-11 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSLAFP00000011770 GO:0001553 biological_process luteinization
ENSLAFP00000011770 GO:0001779 biological_process natural killer cell differentiation
ENSLAFP00000011770 GO:0006351 biological_process transcription, DNA-templated
ENSLAFP00000011770 GO:0007259 biological_process JAK-STAT cascade
ENSLAFP00000011770 GO:0007565 biological_process female pregnancy
ENSLAFP00000011770 GO:0007595 biological_process lactation
ENSLAFP00000011770 GO:0008284 biological_process positive regulation of cell proliferation
ENSLAFP00000011770 GO:0019218 biological_process regulation of steroid metabolic process
ENSLAFP00000011770 GO:0019221 biological_process cytokine-mediated signaling pathway
ENSLAFP00000011770 GO:0019915 biological_process lipid storage
ENSLAFP00000011770 GO:0030155 biological_process regulation of cell adhesion
ENSLAFP00000011770 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSLAFP00000011770 GO:0038161 biological_process prolactin signaling pathway
ENSLAFP00000011770 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSLAFP00000011770 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSLAFP00000011770 GO:0043029 biological_process T cell homeostasis
ENSLAFP00000011770 GO:0043066 biological_process negative regulation of apoptotic process
ENSLAFP00000011770 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSLAFP00000011770 GO:0045579 biological_process positive regulation of B cell differentiation
ENSLAFP00000011770 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSLAFP00000011770 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSLAFP00000011770 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSLAFP00000011770 GO:0046543 biological_process development of secondary female sexual characteristics
ENSLAFP00000011770 GO:0050729 biological_process positive regulation of inflammatory response
ENSLAFP00000011770 GO:0005634 cellular_component nucleus
ENSLAFP00000011770 GO:0005737 cellular_component cytoplasm
ENSLAFP00000011770 GO:0003677 molecular_function DNA binding
ENSLAFP00000011770 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSLAFP00000011770 GO:0004871 molecular_function signal transducer activity
ENSLAFP00000011770 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100012174 7425 Nasonia vitripennis 100121885
7029 Acyrthosiphon pisum 100161101 6087 Hydra magnipapillata 100206878
9601 Pongo abelii 100462537 400682 Amphimedon queenslandica 100641588
30195 Bombus terrestris 100647789 132113 Bombus impatiens 100743540
10029 Cricetulus griseus 100755571 7463 Apis florea 100864112
34638 Metaseiulus occidentalis 100907258 30611 Otolemur garnettii 100958999
9597 Pan paniscus 100988550 9555 Papio anubis 100998364
39432 Saimiri boliviensis 101043203 9669 Mustela putorius furo 101691575
59463 Myotis lucifugus 102423996 9031 Gallus gallus 395556
7460 Apis mellifera 413742 7227 Drosophila melanogaster 42428
9598 Pan troglodytes 454681 9544 Macaca mulatta 574129
7668 Strongylocentrotus purpuratus 576433 7719 Ciona intestinalis 778770
9646 Ailuropoda melanoleuca ENSAMEG00000006061 9913 Bos taurus ENSBTAG00000009496
9615 Canis familiaris ENSCAFG00000015509 9483 Callithrix jacchus ENSCJAG00000000426
51511 Ciona savignyi ENSCSAVG00000011110 9361 Dasypus novemcinctus ENSDNOG00000007398
10020 Dipodomys ordii ENSDORG00000000303 9365 Erinaceus europaeus ENSEEUG00000003642
9371 Echinops telfairi ENSETEG00000008535 9685 Felis catus ENSFCAG00000002153
9595 Gorilla gorilla ENSGGOG00000008216 8049 Gadus morhua ENSGMOG00000014154
7897 Latimeria chalumnae ENSLACG00000002646 9986 Oryctolagus cuniculus 100348267
143995 Megachile rotundata 100880948 10090 Mus musculus 20851
9823 Sus scrofa 397340 7070 Tribolium castaneum 657965
9358 Choloepus hoffmanni ENSCHOG00000005387 10141 Cavia porcellus ENSCPOG00000026466
7955 Danio rerio ENSDARG00000019392 9796 Equus caballus ENSECAG00000007847
69293 Gasterosteus aculeatus ENSGACG00000008634 9315 Macropus eugenii ENSMEUG00000006640
9978 Ochotona princeps ENSOPRG00000008312 8083 Xiphophorus maculatus ENSXMAG00000005165
9103 Meleagris gallopavo ENSMGAG00000003430 30608 Microcebus murinus ENSMICG00000011988
61853 Nomascus leucogenys ENSNLEG00000011444 9258 Ornithorhynchus anatinus ENSOANG00000006496
8128 Oreochromis niloticus ENSONIG00000007261 8090 Oryzias latipes ENSORLG00000003961
9813 Procavia capensis ENSPCAG00000010107 7757 Petromyzon marinus ENSPMAG00000009008
13735 Pelodiscus sinensis ENSPSIG00000015138 132908 Pteropus vampyrus ENSPVAG00000003876
10116 Rattus norvegicus ENSRNOG00000019496 42254 Sorex araneus ENSSARG00000014229
43179 Ictidomys tridecemlineatus ENSSTOG00000006713 37347 Tupaia belangeri ENSTBEG00000009608
59729 Taeniopygia guttata ENSTGUG00000002572 99883 Tetraodon nigroviridis ENSTNIG00000011707
31033 Takifugu rubripes ENSTRUG00000015454 9739 Tursiops truncatus ENSTTRG00000007155
30538 Vicugna pacos ENSVPAG00000005450 8364 Xenopus tropicalis ENSXETG00000000836