Basic Information
Gene ID ENSXMAG00000005165
Gene Name NULL
Full Name Signal transducer and activator of transcription
Organism Xiphophorus maculatus [8083]

Cross Reference
UniProt M3ZSM6 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSXMAP00000005219 Gene3D G3DSA:1.10.238.10 IPR011992 386 511 5.10e-46 EF-hand domain pair
ENSXMAP00000005219 Gene3D G3DSA:1.10.532.10 IPR013799 7 39 6.90e-06 STAT transcription factor, protein interaction
ENSXMAP00000005219 Gene3D G3DSA:1.20.1050.20 IPR013800 53 246 8.70e-63 STAT transcription factor, all-alpha
ENSXMAP00000005219 Gene3D G3DSA:2.60.40.630 IPR012345 247 385 7.60e-68 STAT transcription factor, DNA-binding, subdomain
ENSXMAP00000005219 Gene3D G3DSA:3.30.505.10 IPR000980 512 624 1.10e-43 SH2 domain
ENSXMAP00000005219 PANTHER PTHR11801 IPR001217 8 693 0.00e-00 Transcription factor STAT
ENSXMAP00000005219 Pfam PF00017 IPR000980 509 576 3.60e-10 SH2 domain
ENSXMAP00000005219 Pfam PF01017 IPR013800 52 244 2.60e-56 STAT transcription factor, all-alpha
ENSXMAP00000005219 Pfam PF02864 IPR013801 246 497 1.00e-94 STAT transcription factor, DNA-binding
ENSXMAP00000005219 ProSiteProfiles PS50001 IPR000980 503 604 0.00e-00 SH2 domain
ENSXMAP00000005219 SMART SM00252 IPR000980 501 594 1.50e-07 SH2 domain
ENSXMAP00000005219 SUPERFAMILY SSF47655 IPR015988 51 246 0.00e-00 STAT transcription factor, coiled coil
ENSXMAP00000005219 SUPERFAMILY SSF49417 IPR008967 241 498 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSXMAP00000005219 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSXMAP00000005219 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSXMAP00000005219 PF00017 6.6e-11 SH2 SH2 domain
ENSXMAP00000005219 PF02865 3.5e-06 STAT_int STAT protein, protein interaction domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSXMAP00000005219 GO:0001553 biological_process luteinization
ENSXMAP00000005219 GO:0001779 biological_process natural killer cell differentiation
ENSXMAP00000005219 GO:0006351 biological_process transcription, DNA-templated
ENSXMAP00000005219 GO:0007259 biological_process JAK-STAT cascade
ENSXMAP00000005219 GO:0007565 biological_process female pregnancy
ENSXMAP00000005219 GO:0007595 biological_process lactation
ENSXMAP00000005219 GO:0019218 biological_process regulation of steroid metabolic process
ENSXMAP00000005219 GO:0019915 biological_process lipid storage
ENSXMAP00000005219 GO:0030155 biological_process regulation of cell adhesion
ENSXMAP00000005219 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSXMAP00000005219 GO:0038161 biological_process prolactin signaling pathway
ENSXMAP00000005219 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSXMAP00000005219 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSXMAP00000005219 GO:0043029 biological_process T cell homeostasis
ENSXMAP00000005219 GO:0043066 biological_process negative regulation of apoptotic process
ENSXMAP00000005219 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSXMAP00000005219 GO:0045579 biological_process positive regulation of B cell differentiation
ENSXMAP00000005219 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSXMAP00000005219 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSXMAP00000005219 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSXMAP00000005219 GO:0046543 biological_process development of secondary female sexual characteristics
ENSXMAP00000005219 GO:0050729 biological_process positive regulation of inflammatory response
ENSXMAP00000005219 GO:0005634 cellular_component nucleus
ENSXMAP00000005219 GO:0005737 cellular_component cytoplasm
ENSXMAP00000005219 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSXMAP00000005219 GO:0004871 molecular_function signal transducer activity
ENSXMAP00000005219 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100012174 7425 Nasonia vitripennis 100121885
7029 Acyrthosiphon pisum 100161101 6087 Hydra magnipapillata 100206878
9986 Oryctolagus cuniculus 100348267 9601 Pongo abelii 100462537
400682 Amphimedon queenslandica 100641588 30195 Bombus terrestris 100647789
132113 Bombus impatiens 100743540 10029 Cricetulus griseus 100755571
7463 Apis florea 100864112 143995 Megachile rotundata 100880948
34638 Metaseiulus occidentalis 100907258 30611 Otolemur garnettii 100958999
9597 Pan paniscus 100989105 9555 Papio anubis 101000002
39432 Saimiri boliviensis 101043203 9669 Mustela putorius furo 101691575
59463 Myotis lucifugus 102423996 10090 Mus musculus 20851
9031 Gallus gallus 395556 7460 Apis mellifera 413742
7227 Drosophila melanogaster 42428 9598 Pan troglodytes 454681
9544 Macaca mulatta 574129 7668 Strongylocentrotus purpuratus 576433
7070 Tribolium castaneum 657965 7719 Ciona intestinalis 778770
28377 Anolis carolinensis ENSACAG00000009680 9646 Ailuropoda melanoleuca ENSAMEG00000006061
9913 Bos taurus ENSBTAG00000009496 9615 Canis familiaris ENSCAFG00000015509
9358 Choloepus hoffmanni ENSCHOG00000005387 10141 Cavia porcellus ENSCPOG00000026466
51511 Ciona savignyi ENSCSAVG00000011110 7955 Danio rerio ENSDARG00000019392
9361 Dasypus novemcinctus ENSDNOG00000007398 10020 Dipodomys ordii ENSDORG00000000303
9796 Equus caballus ENSECAG00000007847 9365 Erinaceus europaeus ENSEEUG00000003642
9371 Echinops telfairi ENSETEG00000008528 9685 Felis catus ENSFCAG00000002153
69293 Gasterosteus aculeatus ENSGACG00000008634 9595 Gorilla gorilla ENSGGOG00000008216
8049 Gadus morhua ENSGMOG00000014154 7897 Latimeria chalumnae ENSLACG00000002646
9785 Loxodonta africana ENSLAFG00000014055 9103 Meleagris gallopavo ENSMGAG00000003430
30608 Microcebus murinus ENSMICG00000011988 61853 Nomascus leucogenys ENSNLEG00000011444
9258 Ornithorhynchus anatinus ENSOANG00000006496 8128 Oreochromis niloticus ENSONIG00000007261
9978 Ochotona princeps ENSOPRG00000008312 8090 Oryzias latipes ENSORLG00000003961
9813 Procavia capensis ENSPCAG00000010107 7757 Petromyzon marinus ENSPMAG00000009008
13735 Pelodiscus sinensis ENSPSIG00000015138 132908 Pteropus vampyrus ENSPVAG00000003876
10116 Rattus norvegicus ENSRNOG00000019496 42254 Sorex araneus ENSSARG00000014205
43179 Ictidomys tridecemlineatus ENSSTOG00000006691 37347 Tupaia belangeri ENSTBEG00000009608
59729 Taeniopygia guttata ENSTGUG00000002572 99883 Tetraodon nigroviridis ENSTNIG00000011707
31033 Takifugu rubripes ENSTRUG00000015454 9478 Tarsius syrichta ENSTSYG00000000267
9739 Tursiops truncatus ENSTTRG00000007155 30538 Vicugna pacos ENSVPAG00000005450
8364 Xenopus tropicalis ENSXETG00000000836 9823 Sus scrofa 397340
9315 Macropus eugenii ENSMEUG00000006640

Paralogs
ENSXMAG00000014535