Basic Information
Gene ID ENSRNOG00000007975 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Ncoa2
Full Name Nuclear receptor coactivator 2
Organism Rattus norvegicus [10116]

Cross Reference
UniProt F1MA61 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSRNOP00000011026 Gene3D G3DSA:4.10.280.10 IPR011598 32 100 9.20e-06 Myc-type, basic helix-loop-helix (bHLH) domain
ENSRNOP00000011026 Gene3D G3DSA:4.10.630.10 IPR008955 638 647 5.10e-09 Nuclear receptor coactivator Src-1
ENSRNOP00000011026 Gene3D G3DSA:4.10.630.10 IPR008955 684 709 5.10e-09 Nuclear receptor coactivator Src-1
ENSRNOP00000011026 PANTHER PTHR10684 IPR017426 2 1465 0.00e-00 Nuclear receptor coactivator
ENSRNOP00000011026 PANTHER PTHR10684:SF2 IPR028822 2 1465 0.00e-00 Nuclear receptor coactivator 2
ENSRNOP00000011026 Pfam PF00989 IPR013767 119 176 3.30e-07 PAS fold
ENSRNOP00000011026 Pfam PF07469 IPR010011 1281 1338 6.60e-27 Domain of unknown function DUF1518
ENSRNOP00000011026 Pfam PF08815 IPR014920 1071 1117 1.50e-22 Nuclear receptor coactivator, Ncoa-type, interlocking
ENSRNOP00000011026 Pfam PF08832 IPR014935 636 709 2.20e-25 Steroid receptor coactivator
ENSRNOP00000011026 PIRSF PIRSF038181 IPR017426 1 1465 0.00e-00 Nuclear receptor coactivator
ENSRNOP00000011026 ProSiteProfiles PS50112 IPR000014 119 183 0.00e-00 PAS domain
ENSRNOP00000011026 ProSiteProfiles PS50888 IPR011598 26 83 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSRNOP00000011026 SMART SM00086 IPR001610 334 377 4.50e-03 PAC motif
ENSRNOP00000011026 SMART SM00091 IPR000014 114 181 8.50e-13 PAS domain
ENSRNOP00000011026 SMART SM00353 IPR011598 32 89 7.30e-11 Myc-type, basic helix-loop-helix (bHLH) domain
ENSRNOP00000011026 SUPERFAMILY SSF47459 IPR011598 32 92 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSRNOP00000011026 SUPERFAMILY SSF55785 IPR000014 123 190 0.00e-00 PAS domain
ENSRNOP00000011026 SUPERFAMILY SSF55785 IPR000014 268 372 0.00e-00 PAS domain
ENSRNOP00000011026 SUPERFAMILY SSF69125 IPR009110 1069 1114 0.00e-00 Nuclear receptor coactivator, interlocking

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSRNOP00000011026 PF14598 3.5e-37 PAS_11 PAS domain
ENSRNOP00000011026 PF07469 6.6e-27 DUF1518 Domain of unknown function (DUF1518)
ENSRNOP00000011026 PF08832 2.2e-25 SRC-1 Steroid receptor coactivator
ENSRNOP00000011026 PF08815 4.8e-23 Nuc_rec_co-act Nuclear receptor coactivator
ENSRNOP00000011026 PF00989 6e-08 PAS PAS fold
ENSRNOP00000011026 PF13426 8.3e-07 PAS_9 PAS domain
ENSRNOP00000011026 PF08447 8.4e-05 PAS_3 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSRNOP00000011026 GO:0006351 biological_process transcription, DNA-templated
ENSRNOP00000011026 GO:0005634 cellular_component nucleus
ENSRNOP00000011026 GO:0003713 molecular_function transcription coactivator activity
ENSRNOP00000011026 GO:0004402 molecular_function histone acetyltransferase activity
ENSRNOP00000011026 GO:0004871 molecular_function signal transducer activity
ENSRNOP00000011026 GO:0030374 molecular_function ligand-dependent nuclear receptor transcription coactivator activity
ENSRNOP00000011026 GO:0035257 molecular_function nuclear hormone receptor binding
ENSRNOP00000011026 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100161757 30195 Bombus terrestris 100648067
7425 Nasonia vitripennis 100680400 132113 Bombus impatiens 100747735
143995 Megachile rotundata 100877371 9597 Pan paniscus 100976890
9555 Papio anubis 101011914 39432 Saimiri boliviensis 101031553
9595 Gorilla gorilla 101143868 8083 Xiphophorus maculatus 102226120
13735 Pelodiscus sinensis 102456412 9606 Homo sapiens 10499
10090 Mus musculus 17978 9598 Pan troglodytes 464226
7070 Tribolium castaneum 656017 9646 Ailuropoda melanoleuca ENSAMEG00000006233
9358 Choloepus hoffmanni ENSCHOG00000000075 10141 Cavia porcellus ENSCPOG00000000493
7955 Danio rerio ENSDARG00000017929 9361 Dasypus novemcinctus ENSDNOG00000014500
10020 Dipodomys ordii ENSDORG00000010899 9796 Equus caballus ENSECAG00000008394
9365 Erinaceus europaeus ENSEEUG00000004088 9371 Echinops telfairi ENSETEG00000018046
9685 Felis catus ENSFCAG00000032000 69293 Gasterosteus aculeatus ENSGACG00000002822
8049 Gadus morhua ENSGMOG00000016251 7897 Latimeria chalumnae ENSLACG00000017459
9785 Loxodonta africana ENSLAFG00000009117 9315 Macropus eugenii ENSMEUG00000002794
9103 Meleagris gallopavo ENSMGAG00000011424 30608 Microcebus murinus ENSMICG00000002452
59463 Myotis lucifugus ENSMLUG00000012692 9544 Macaca mulatta ENSMMUG00000015978
13616 Monodelphis domestica ENSMODG00000007376 9669 Mustela putorius furo ENSMPUG00000010623
9258 Ornithorhynchus anatinus ENSOANG00000001949 9986 Oryctolagus cuniculus ENSOCUG00000005967
30611 Otolemur garnettii ENSOGAG00000013213 8128 Oreochromis niloticus ENSONIG00000014253
9978 Ochotona princeps ENSOPRG00000015038 8090 Oryzias latipes ENSORLG00000008098
132908 Pteropus vampyrus ENSPVAG00000009208 42254 Sorex araneus ENSSARG00000006140
9305 Sarcophilus harrisii ENSSHAG00000014604 9823 Sus scrofa ENSSSCG00000006194
43179 Ictidomys tridecemlineatus ENSSTOG00000012735 37347 Tupaia belangeri ENSTBEG00000007600
59729 Taeniopygia guttata ENSTGUG00000011459 99883 Tetraodon nigroviridis ENSTNIG00000008193
31033 Takifugu rubripes ENSTRUG00000011789 9478 Tarsius syrichta ENSTSYG00000000545
30538 Vicugna pacos ENSVPAG00000010738 8364 Xenopus tropicalis ENSXETG00000015926
9739 Tursiops truncatus ENSTTRG00000013003