Basic Information
Gene ID ENSXETG00000015926
Gene Name ncoa2
Full Name Nuclear receptor coactivator 2
Organism Xenopus tropicalis [8364]

Cross Reference
UniProt F6SV40 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSXETP00000034772 Gene3D G3DSA:4.10.280.10 IPR011598 29 96 4.50e-05 Myc-type, basic helix-loop-helix (bHLH) domain
ENSXETP00000034772 Gene3D G3DSA:4.10.630.10 IPR008955 625 634 2.80e-08 Nuclear receptor coactivator Src-1
ENSXETP00000034772 Gene3D G3DSA:4.10.630.10 IPR008955 675 700 2.80e-08 Nuclear receptor coactivator Src-1
ENSXETP00000034772 PANTHER PTHR10684 IPR017426 1 1489 0.00e-00 Nuclear receptor coactivator
ENSXETP00000034772 PANTHER PTHR10684:SF2 IPR028822 1 1489 0.00e-00 Nuclear receptor coactivator 2
ENSXETP00000034772 Pfam PF00989 IPR013767 116 171 3.10e-06 PAS fold
ENSXETP00000034772 Pfam PF07469 IPR010011 1271 1327 6.20e-17 Domain of unknown function DUF1518
ENSXETP00000034772 Pfam PF07469 IPR010011 1341 1397 3.00e-22 Domain of unknown function DUF1518
ENSXETP00000034772 Pfam PF08815 IPR014920 1064 1108 3.40e-18 Nuclear receptor coactivator, Ncoa-type, interlocking
ENSXETP00000034772 Pfam PF08832 IPR014935 623 700 2.10e-27 Steroid receptor coactivator
ENSXETP00000034772 PIRSF PIRSF038181 IPR017426 1 1492 0.00e-00 Nuclear receptor coactivator
ENSXETP00000034772 ProSiteProfiles PS50112 IPR000014 116 180 0.00e-00 PAS domain
ENSXETP00000034772 ProSiteProfiles PS50888 IPR011598 23 80 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSXETP00000034772 SMART SM00091 IPR000014 111 178 3.20e-12 PAS domain
ENSXETP00000034772 SMART SM00353 IPR011598 29 86 3.50e-10 Myc-type, basic helix-loop-helix (bHLH) domain
ENSXETP00000034772 SUPERFAMILY SSF47459 IPR011598 29 86 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSXETP00000034772 SUPERFAMILY SSF55785 IPR000014 120 193 0.00e-00 PAS domain
ENSXETP00000034772 SUPERFAMILY SSF55785 IPR000014 259 362 0.00e-00 PAS domain
ENSXETP00000034772 SUPERFAMILY SSF69125 IPR009110 1060 1106 0.00e-00 Nuclear receptor coactivator, interlocking

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSXETP00000034772 PF14598 7.7e-37 PAS_11 PAS domain
ENSXETP00000034772 PF07469 1.5e-36 DUF1518 Domain of unknown function (DUF1518)
ENSXETP00000034772 PF08832 2.1e-27 SRC-1 Steroid receptor coactivator
ENSXETP00000034772 PF08815 1.1e-18 Nuc_rec_co-act Nuclear receptor coactivator
ENSXETP00000034772 PF00989 2.6e-07 PAS PAS fold
ENSXETP00000034772 PF13426 0.00011 PAS_9 PAS domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSXETP00000034772 GO:0006351 biological_process transcription, DNA-templated
ENSXETP00000034772 GO:0005634 cellular_component nucleus
ENSXETP00000034772 GO:0003713 molecular_function transcription coactivator activity
ENSXETP00000034772 GO:0004402 molecular_function histone acetyltransferase activity
ENSXETP00000034772 GO:0004871 molecular_function signal transducer activity
ENSXETP00000034772 GO:0030374 molecular_function ligand-dependent nuclear receptor transcription coactivator activity
ENSXETP00000034772 GO:0035257 molecular_function nuclear hormone receptor binding
ENSXETP00000034772 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13735 Pelodiscus sinensis 102456412 10020 Dipodomys ordii ENSDORG00000010899
10116 Rattus norvegicus ENSRNOG00000007975 31033 Takifugu rubripes ENSTRUG00000011789
9739 Tursiops truncatus ENSTTRG00000013003 7029 Acyrthosiphon pisum 100161757
30195 Bombus terrestris 100648067 7425 Nasonia vitripennis 100680400
132113 Bombus impatiens 100747735 143995 Megachile rotundata 100877371
9597 Pan paniscus 100976890 9555 Papio anubis 101011914
39432 Saimiri boliviensis 101031553 9595 Gorilla gorilla 101143868
8083 Xiphophorus maculatus 102226120 9606 Homo sapiens 10499
10090 Mus musculus 17978 9598 Pan troglodytes 464226
7070 Tribolium castaneum 656017 9646 Ailuropoda melanoleuca ENSAMEG00000006233
9358 Choloepus hoffmanni ENSCHOG00000000075 10141 Cavia porcellus ENSCPOG00000000493
7955 Danio rerio ENSDARG00000017929 9361 Dasypus novemcinctus ENSDNOG00000014500
9796 Equus caballus ENSECAG00000008394 9365 Erinaceus europaeus ENSEEUG00000004088
9371 Echinops telfairi ENSETEG00000018046 9685 Felis catus ENSFCAG00000032000
69293 Gasterosteus aculeatus ENSGACG00000002822 8049 Gadus morhua ENSGMOG00000016251
7897 Latimeria chalumnae ENSLACG00000017459 9785 Loxodonta africana ENSLAFG00000009117
9315 Macropus eugenii ENSMEUG00000002794 9103 Meleagris gallopavo ENSMGAG00000011424
30608 Microcebus murinus ENSMICG00000002452 59463 Myotis lucifugus ENSMLUG00000012692
9544 Macaca mulatta ENSMMUG00000015978 13616 Monodelphis domestica ENSMODG00000007376
9669 Mustela putorius furo ENSMPUG00000010623 9258 Ornithorhynchus anatinus ENSOANG00000001949
9986 Oryctolagus cuniculus ENSOCUG00000005967 30611 Otolemur garnettii ENSOGAG00000013213
8128 Oreochromis niloticus ENSONIG00000014253 9978 Ochotona princeps ENSOPRG00000015038
8090 Oryzias latipes ENSORLG00000005783 7757 Petromyzon marinus ENSPMAG00000002534
132908 Pteropus vampyrus ENSPVAG00000009208 42254 Sorex araneus ENSSARG00000006140
9305 Sarcophilus harrisii ENSSHAG00000014604 9823 Sus scrofa ENSSSCG00000006194
43179 Ictidomys tridecemlineatus ENSSTOG00000012735 37347 Tupaia belangeri ENSTBEG00000007600
59729 Taeniopygia guttata ENSTGUG00000011459 99883 Tetraodon nigroviridis ENSTNIG00000008193
9478 Tarsius syrichta ENSTSYG00000000545 30538 Vicugna pacos ENSVPAG00000010738