Basic Information
Gene ID ENSSTOG00000006713
Gene Name STAT5A
Full Name Signal transducer and activator of transcription
Organism Ictidomys tridecemlineatus [43179]

Cross Reference
UniProt I3M8F2 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSTOP00000006019 Gene3D G3DSA:1.10.238.10 IPR011992 465 590 2.80e-46 EF-hand domain pair
ENSSTOP00000006019 Gene3D G3DSA:1.10.532.10 IPR013799 1 126 8.90e-49 STAT transcription factor, protein interaction
ENSSTOP00000006019 Gene3D G3DSA:1.20.1050.20 IPR013800 139 227 6.40e-14 STAT transcription factor, all-alpha
ENSSTOP00000006019 Gene3D G3DSA:1.20.1050.20 IPR013800 272 325 4.70e-17 STAT transcription factor, all-alpha
ENSSTOP00000006019 Gene3D G3DSA:2.60.40.630 IPR012345 326 464 2.60e-69 STAT transcription factor, DNA-binding, subdomain
ENSSTOP00000006019 Gene3D G3DSA:3.30.505.10 IPR000980 591 701 1.90e-38 SH2 domain
ENSSTOP00000006019 PANTHER PTHR11801 IPR001217 2 767 0.00e-00 Transcription factor STAT
ENSSTOP00000006019 Pfam PF00017 IPR000980 588 661 1.20e-10 SH2 domain
ENSSTOP00000006019 Pfam PF01017 IPR013800 138 227 4.50e-10 STAT transcription factor, all-alpha
ENSSTOP00000006019 Pfam PF01017 IPR013800 272 323 1.00e-12 STAT transcription factor, all-alpha
ENSSTOP00000006019 Pfam PF02864 IPR013801 325 576 3.40e-99 STAT transcription factor, DNA-binding
ENSSTOP00000006019 Pfam PF02865 IPR013799 2 125 3.80e-48 STAT transcription factor, protein interaction
ENSSTOP00000006019 ProSiteProfiles PS50001 IPR000980 582 679 0.00e-00 SH2 domain
ENSSTOP00000006019 SMART SM00252 IPR000980 580 681 6.90e-08 SH2 domain
ENSSTOP00000006019 SMART SM00964 IPR013799 2 126 5.30e-66 STAT transcription factor, protein interaction
ENSSTOP00000006019 SUPERFAMILY SSF47655 IPR015988 136 213 0.00e-00 STAT transcription factor, coiled coil
ENSSTOP00000006019 SUPERFAMILY SSF47655 IPR015988 272 325 0.00e-00 STAT transcription factor, coiled coil
ENSSTOP00000006019 SUPERFAMILY SSF48092 IPR013799 1 125 0.00e-00 STAT transcription factor, protein interaction
ENSSTOP00000006019 SUPERFAMILY SSF49417 IPR008967 320 577 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSTOP00000006019 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSSTOP00000006019 PF02865 0 STAT_int STAT protein, protein interaction domain
ENSSTOP00000006019 PF01017 3.3e-25 STAT_alpha STAT protein, all-alpha domain
ENSSTOP00000006019 PF00017 1e-11 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSTOP00000006019 GO:0001553 biological_process luteinization
ENSSTOP00000006019 GO:0001779 biological_process natural killer cell differentiation
ENSSTOP00000006019 GO:0006351 biological_process transcription, DNA-templated
ENSSTOP00000006019 GO:0007259 biological_process JAK-STAT cascade
ENSSTOP00000006019 GO:0007565 biological_process female pregnancy
ENSSTOP00000006019 GO:0007595 biological_process lactation
ENSSTOP00000006019 GO:0019218 biological_process regulation of steroid metabolic process
ENSSTOP00000006019 GO:0019915 biological_process lipid storage
ENSSTOP00000006019 GO:0030155 biological_process regulation of cell adhesion
ENSSTOP00000006019 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSSTOP00000006019 GO:0038161 biological_process prolactin signaling pathway
ENSSTOP00000006019 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSSTOP00000006019 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSSTOP00000006019 GO:0043029 biological_process T cell homeostasis
ENSSTOP00000006019 GO:0043066 biological_process negative regulation of apoptotic process
ENSSTOP00000006019 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSSTOP00000006019 GO:0045579 biological_process positive regulation of B cell differentiation
ENSSTOP00000006019 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSSTOP00000006019 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSSTOP00000006019 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSSTOP00000006019 GO:0046543 biological_process development of secondary female sexual characteristics
ENSSTOP00000006019 GO:0050729 biological_process positive regulation of inflammatory response
ENSSTOP00000006019 GO:0005634 cellular_component nucleus
ENSSTOP00000006019 GO:0005737 cellular_component cytoplasm
ENSSTOP00000006019 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSSTOP00000006019 GO:0004871 molecular_function signal transducer activity
ENSSTOP00000006019 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9598 Pan troglodytes 454681 9544 Macaca mulatta 574129
10020 Dipodomys ordii ENSDORG00000000303 9685 Felis catus ENSFCAG00000002153
9258 Ornithorhynchus anatinus ENSOANG00000006496 400682 Amphimedon queenslandica 100641588
10029 Cricetulus griseus 100755571 30611 Otolemur garnettii 100958999
9597 Pan paniscus 100988550 9555 Papio anubis 100998364
9669 Mustela putorius furo 101691575 59463 Myotis lucifugus 102423996
9913 Bos taurus ENSBTAG00000009496 9483 Callithrix jacchus ENSCJAG00000000426
9785 Loxodonta africana ENSLAFG00000014055 9813 Procavia capensis ENSPCAG00000010107
13735 Pelodiscus sinensis ENSPSIG00000015138 10116 Rattus norvegicus ENSRNOG00000019496
9739 Tursiops truncatus ENSTTRG00000007155

Paralogs
ENSSTOG00000006691